Archived Medical News Stories

RSSArchived Drug Trial News Stories - July 2012

Date Title Comments Rating
2012-07-31 InSite Vision commences enrollment in BromSite Phase 3 clinical trial 0 None
2012-07-31 Array BioPharma announces positive results from ARRY-797 Phase 2 trial on osteoarthritis 0 None
2012-07-31 GenSpera receives FDA clearance to commence G-202 Phase II trial in prostate cancer 0 None
2012-07-31 Latrepirdine appears effective in treating Alzheimer's disease in animals 0 5
2012-07-31 Top-line results from Pfizer's tofacitinib Phase 3 study on moderate-to-severe active RA 2 None
2012-07-30 New drug shows promise for Long QT syndrome 0 None
2012-07-30 FDA grants Senesco's SNS01-T orphan-drug designation to treat lymphomas 0 None
2012-07-30 Encouraging results from Tonix TNX-102 SL clinical trial for fibromyalgia syndrome 4 3
2012-07-30 Positive results from XIAFLEX phase IIIb multicord trial for Dupuytren's contracture 0 None
2012-07-30 Positive results from Vermillion OVA500 multi-center study for ovarian cancer 0 None
2012-07-30 Advaxis reports continued positive patient survival pattern in ADXS-HPV Phase 2 cervical cancer trial 0 None
2012-07-30 Early ART treatment delays AIDS-related health events in HIV-infected individuals 0 None
2012-07-30 Scientists discover new way to combat post-surgical scarring for glaucoma patients 0 None
2012-07-30 Paper highlights clinical and immunological activity of immatics’ IMA901 in renal cell carcinoma 0 5
2012-07-28 Genentech's BREVACTA study of ACTEMRA on rheumatoid arthritis meets primary endpoint 0 None
2012-07-28 Economist articles, blog examine research presented at AIDS 2012 conference 0 None
2012-07-28 Experimental dengue vaccine protects against 3 of 4 viral strains, study results show 0 None
2012-07-28 ARIAD Pharmaceuticals commences ponatinib Phase 3 trial in newly diagnosed CML 0 None
2012-07-28 Rituximab also benefits patients with kidney disorder 0 None
2012-07-27 TB combination drug: an interview with Mel Spigelman, MD, CEO and President of TB Alliance 0 None
2012-07-27 Anakinra can dramatically limit amount of brain damage in stroke patients 0 None
2012-07-27 HPTN study results show additional benefits of early ART in HIV clinical outcomes 0 None
2012-07-27 Navidea announces results from Lymphoseek Phase 3 trial on head and neck squamous cell carcinoma 0 None
2012-07-26 Preliminary findings from Protalex's PRTX-100 Phase 1b study on active rheumatoid arthritis 0 None
2012-07-26 New association found between basal cell carcinoma and eczema 0 None
2012-07-26 Raising dopamine levels in frontal cortex reduces impulsivity in healthy adults 0 None
2012-07-26 Bio-Path initiates enrollment in fourth cohort of Liposomal Grb-2 Phase I trial for blood cancers 0 None
2012-07-26 Multi-center clinical trial results demonstrate safety and efficacy of carfilzomib for multiple myeloma 0 4
2012-07-26 ImmunoCellular receives FDA IND clearance for ICT-121 Phase I trial in glioblastoma multiforme 0 None
2012-07-26 Bard completes enrollment in Lutonix DCB clinical trial for peripheral arterial disease 0 3
2012-07-26 Jennerex initiates JX-594 Phase 2 trial in advanced hepatocellular carcinoma 0 None
2012-07-26 CytRx commences aldoxorubicin plus doxorubicin Phase 1b trial in advanced solid tumors 0 None
2012-07-25 Karyopharm commences two KPT-330 phase 1 studies in cancers 0 None
2012-07-25 EntreMed commences ENMD-2076 Phase 2 study in triple-negative breast cancer 0 None
2012-07-25 New combination therapy for TB shows promise in Phase II study 0 None
2012-07-25 NBTI participates in ICT-107 phase II trial for glioblastoma multiforme 1 None
2012-07-25 Merck signs two licensing agreements for investigational HIV drug candidates 0 None
2012-07-25 Little evidence exists for potential HPV type competition in cross-sectional study 0 None
2012-07-25 Dapivirine Phase III trial now underway in Africa to treat HIV in women 0 None
2012-07-25 Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout 0 None
2012-07-24 Novel combination drug regimen could be more effective than existing treatments for TB 0 None
2012-07-24 Topline results from first of four Phase 3 studies of Pfizer's bapineuzumab for Alzheimer's 0 None
2012-07-24 Pfizer’s Lyrica does not affect reproductive function in healthy males 0 None
2012-07-24 Debiopharm initiates Debio 8206 Phase III study on advanced prostate cancer 0 None
2012-07-24 TB combination drug trials progress 0 None
2012-07-24 Top-line result from Pfizer Bapineuzumab Phase 3 studies on Alzheimer's 0 None
2012-07-24 XenoPort initiates XP23829 Phase 1 study in healthy adults 0 None
2012-07-24 Ocular Therapeutix announces results from sustained release OTX-TP1 study on glaucoma 0 None
2012-07-24 Eating raisins may provide the same workout boost as sports chews 0 None
2012-07-23 Once-daily Gralise significantly reduces pain intensity in PHN patients 0 None
2012-07-23 New investment to fund Chiasma's Octreolin Phase 3 pivotal program for acromegaly 0 1
2012-07-23 Berg Pharma initiates BPM 31543 clinical trial for chemotherapy-induced alopecia 0 None
2012-07-23 Top-line results in Pfizer's Lyrica long term safety study for Generalized Anxiety Disorder 0 1
2012-07-23 Positive results from BrainStorm's interim NurOwn stem cell therapy clinical trial for ALS 7 None
2012-07-23 Cerulean commences dosing in CRLX101 Phase 2 study for ovarian cancer 0 None
2012-07-23 FDA meeting confirms Orexo regulatory submission of OX219 NDA on track 0 None
2012-07-23 Linagliptin safe and effective for long-term management of type 2 diabetes 0 None
2012-07-23 Foundation Fighting Blindness grants US$125,000 to Oxford BioMedica for UshStat Phase I/IIa trial 0 None
2012-07-23 Bayer, Onyx and Astellas announce results from Tarceva plus Nexavar Phase 3 trial on HCC 0 5
2012-07-23 Study addresses African patients’ attitudes toward HIV antiretroviral therapy 0 None
2012-07-22 BioDiem presents positive findings of their eye disease drug at international conference 0 None
2012-07-21 FDA grants accelerated approval for Kyprolis to treat multiple myeloma 0 None
2012-07-21 EMA CHMP issues positive opinion for conditional approval of brentuximab vedotin for lymphoma 0 None
2012-07-21 Regeneron, Sanofi initiate enrollment in SAR236553/REGN727 Phase 3 program 0 None
2012-07-20 Phosphate binders may cause unexpected harm to blood vessels in patients with CKD 1 3.3
2012-07-20 Silymarin does not offer significant improvements for patients with HCV 0 None
2012-07-20 T2Hemostasis provides reliable and rapid results when compared to conventional systems 0 None
2012-07-20 Bristol-Myers Squibb reports results from brivanib plus sorafenib phase III trial on HCC 0 4.3
2012-07-20 Conatus, University of Alberta initiate islet cell transplant Phase I/II trial of emricasan for diabetes 0 None
2012-07-20 Actinium completes Actimab-A Phase I/II study on Acute Myeloid Leukemia 0 None
2012-07-20 Viral Genetics initiates Phase 1 trial of MDT compounds for ovarian cancer 0 None
2012-07-19 NPR reports on Brazilian clinical trial of Truvada as prevention strategy 0 None
2012-07-19 Clinical trial to evaluate maraviroc-based PrEP regimens for HIV prevention 0 None
2012-07-19 Positive preliminary results from Feraheme phase III study on iron deficiency anemia 0 None
2012-07-19 Otsuka, Acucela commence rebamipide ophthalmic suspension Phase 3 trial in dry eye syndrome 0 None
2012-07-19 Angion Biomedica initiates BB3 Phase II trial in heart attack 0 None
2012-07-18 Silymarin does not provide greater benefit for patients with chronic HCV infection 0 None
2012-07-18 Combination prevention strategy trials to start later this year in Africa, GlobalPost reports 0 None
2012-07-18 Memantine boosts memory function in people with Down syndrome 1 5
2012-07-17 Anthera announces final set of clinical data from blisibimod Phase 2b study on SLE 0 None
2012-07-17 AstraZeneca plans to conduct ticagrelor plus clopidogrel clinical trial for PAD 0 5
2012-07-17 D-ribose effective in improving QOL in energy-depleted patients with FMS/CFS 0 5
2012-07-16 Positive results from Alnylam’s ALN-TTR02 Phase I trial on TTR-mediated amyloidosis 0 None
2012-07-16 Merck to present results from clinical studies on BACE inhibitors at AAIC 2012 0 None
2012-07-14 James J. Peters Veterans Hospital actively enrolls participants for NIC5-15 phase IIb trial in AD 0 5
2012-07-13 ACT treats fourth patient in U.S. clinical trial for Stargardt's Macular Dystrophy 1 5
2012-07-13 OncoMed commences dosing in OMP-54F28 Phase I clinical trial for advanced solid tumor cancers 0 None
2012-07-13 Cubist initiates CB-315 Phase 3 trial for Clostridium difficile-associated diarrhea 0 None
2012-07-12 Nottingham researchers to lead Avastin clinical study for AMD 0 None
2012-07-12 Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation 0 None
2012-07-12 New drug combination could offer hope to children with neuroblastoma 0 None
2012-07-12 Merck announces update on odanacatib Phase III trial for osteoporosis 0 None
2012-07-12 NOXXON commences Spiegelmer NOX-A12 Phase IIa trial in CLL 0 5
2012-07-12 Enrollment complete in Phase III IND study of Spinal Restoration's Biostat System 0 None
2012-07-12 Dolutegravir-based regimen demonstrates superiority over Atripla in treatment-naive adults with HIV-1 0 None
2012-07-11 Arrowhead initiates Adipotide Phase 1 trial in obesity 3 4
2012-07-11 BioInvent announces data from BI-204 phase IIa study on stable atherosclerotic vascular disease 0 None
2012-07-11 OncoSec establishes UCSF as second enrolling site for OMS-I110 Phase II Merkel cell carcinoma trial 0 None
2012-07-11 ImmunoGen announces start of IMGN853 Phase I trial for ovarian cancer, other solid tumors 0 None
2012-07-11 Chemotherapy improves survival for patients with periampullary cancer following resection 0 None
2012-07-11 HIV infection risk reduced by same drugs that treat HIV 0 None
2012-07-11 Nutrient cocktail can boost memory in patients with mild cognitive impairment 0 None
2012-07-10 Inovio commences SynCon vaccine phase I study in H1N1 influenza 0 None
2012-07-10 Inspiration receives FDA clinical hold order for IB1001 phase III studies on hemophilia B 0 None
2012-07-10 Iron supplementation decreases fatigue by almost 50% in nonanemic women 0 None
2012-07-09 Enrollment complete in Lux Biosciences Luveniq Phase 3 study for non-infectious uveitis 0 None
2012-07-09 Positive data from Tonix's sublingual TNX-102 PK study for fibromyalgia 0 None
2012-07-09 Acusphere completes MAA dossier for Imagify to detect CAD 0 None
2012-07-09 Positive interim results from Inspiration's OBI-1 Phase 2/3 study for acquired hemophilia A 0 None
2012-07-09 Ampio announces results from Optina trial on DME 0 None
2012-07-08 Bayer commences enrollment in BAY94-9027 Phase II/III trial for hemophilia A 0 None
2012-07-07 New Gateway-funded phase II ADAPT study for metastatic colorectal cancer 0 None
2012-07-06 Fingolimod offers minor added benefit for patients with RRMS 0 None
2012-07-06 Higher doses of Vitamin D may be most beneficial in reducing bone fractures in older adults 0 None
2012-07-05 Preventing post-operative delirium may improve recovery of cognitive ability in cardiac patients 0 None
2012-07-05 Eltrombopag can raise blood cell levels in some people with severe aplastic anemia 0 None
2012-07-05 Anti-cancer activity of HuCAL antibody revealed by new data from OncoMed 0 None
2012-07-04 Cancer Therapeutics reveals proof of concept for second development drug 0 None
2012-07-04 Live zoster vaccine associated with reduced risk of HZ in patients with immune-mediated diseases 0 None
2012-07-04 Shingles vaccine may not increase risk of varicella in people with auto-immune diseases 0 None
2012-07-04 TMC receives NIH grant to evaluate pepducin in heart disease patients 0 None
2012-07-03 Botulinum toxin may help prevent arm tremor in people with MS 0 None
2012-07-03 Savient's KRYSTEXXA improves HRQOL and physical function in patients with RCG 0 None
2012-07-02 ImmunoCellular to expand ICT-107 Phase IIb trial on GBM 0 None
2012-07-02 Onyx commences ENDEAVOR Kyprolis Phase 3 trial for relapsed multiple myeloma 0 None
2012-07-02 Cerulean commences dosing in CRLX101-Avastin combination study for metastatic renal cell carcinoma 0 None
2012-07-02 Enrollment complete in Cerulean CRLX101 Phase 2 study for non-small cell lung cancer 0 None
2012-07-02 Rexahn submits RX-5902 IND to FDA for treatment of advanced or metastatic solid tumors 0 None
2012-07-02 Sosei completes SO-1105 Phase I trial for oropharyngeal candidiasis in Japan 0 None
2012-07-02 Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB 0 3
2012-07-02 Clinical results for Teva's biologic oncology candidates presented at MASCC/ISOO 2012 0 None


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