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Miscarriage and molecular signals: an interview with Prof Brosens and Prof Quenby

Miscarriage is defined as the spontaneous loss of pregnancy before the baby reaches viability. Besides the physical trauma, miscarriage causes considerable anxiety, stress, and depression.

17 Jan 2013

Continued investment needed to maintain gains against malaria

In this post in Management Sciences for Health's (MSH) "Global Health Impact" blog, Frederick Hartman, the global technical lead for communicable diseases and epidemic preparedness, and regional portfolio director, East Africa at the Center for Health Services at MSH, examines advances made in malaria control over the past decade, writing, "Malaria is still one of the five leading causes of child under-five mortality worldwide, and deserves continuing attention."

17 Jan 2013

H1N1 flu vaccination during pregnancy does not increase risk of fetal loss

Norwegian pregnant women who received a vaccine against the 2009 H1N1 influenza virus showed no increased risk of pregnancy loss, while pregnant women who experienced influenza during pregnancy had an increased risk of miscarriages and still births, a study has found. The study suggests that influenza infection may increase the risk of fetal loss.

17 Jan 2013

Eyes also need light to develop normally during pregnancy

New research in Nature concludes the eye – which depends on light to see – also needs light to develop normally during pregnancy.

17 Jan 2013

U-M researchers to develop disorders of sex development decision-making tools for parents

When a child is born with a disorder of sex development, decisions regarding gender assignment and genital surgery are often made quickly and under pressure.

17 Jan 2013

UCI study identifies transgenerational effects of tributyltin

Exposing pregnant mice to low doses of the chemical tributyltin - which is used in marine hull paint and PVC plastic - can lead to obesity for multiple generations without subsequent exposure, a UC Irvine study has found.

17 Jan 2013

Some children with autism lose symptoms and diagnosis as they grow older

Some children who are accurately diagnosed in early childhood with autism lose the symptoms and the diagnosis as they grow older, a study supported by the National Institutes of Health has confirmed. The research team made the finding by carefully documenting a prior diagnosis of autism in a small group of school-age children and young adults with no current symptoms of the disorder.

16 Jan 2013

India marks two years since last diagnosed polio case

On January 13, India "completed two years since the last case of the crippling disease was reported ... a huge achievement for a country that as recently as 2009 reported 741 cases of polio -- more than any other country in the world, and almost half of cases reported globally that year," the Wall Street Journal's "India Real Time" blog reports.

16 Jan 2013

WHO recommends switching to injectable polio vaccine

"[T]his month the World Health Organization (WHO) in Geneva, Switzerland, proposed a shift in [polio] vaccination strategy from oral vaccines to injected ones that may have to be administered in clinics," Nature reports, adding, "The change is needed to mop up the last remaining pockets of polio, but experts say that it poses challenges in [rural areas], which have poor access to health care."

16 Jan 2013

Stem cell transplantation prevents decrease in heart function associated with DMD

Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD.

16 Jan 2013

Study identifies 24 new copy number variants linked with autism

University of Utah (the U) researchers, in collaboration with several groups from around the country, published a paper on Monday, Jan. 14, 2013, following one of the biggest studies of its kind, that extends our understanding of genes related to autism spectrum diseases (ASDs) and advances methods for early detection and treatment.

16 Jan 2013

Experts blame lack of immunization coverage for Pakistan's measles outbreak

In 2012, measles "claimed the lives of more than 300 children in Pakistan," with more than 200 of those deaths from Sindh province, and health experts and the WHO are saying "the huge difference in routine immunization coverage between the provinces, districts and cities is at the root of the measles outbreak," Inter Press Service reports.

16 Jan 2013

CHOP to study antibiotic delivery to children after hospitalization for serious bacterial infection

The Children's Hospital of Philadelphia (CHOP) was awarded nearly $2M in research funding from the Patient-Centered Outcomes Research Institute (PCORI) to study antibiotic delivery to children returning home after hospitalization for a severe bacterial infection.

16 Jan 2013

Genetics researchers identify 25 additional copy number variations associated with autism

Genetics researchers have identified 25 additional copy number variations (CNVs)—missing or duplicated stretches of DNA—that occur in some patients with autism. These CNVs, say the researchers, are "high impact": although individually rare, each has a strong effect in raising an individual's risk for autism.

16 Jan 2013

Pfizer’s Quillivant XR now available in the U.S. for treatment of ADHD

Pfizer Inc. today announced that Quillivant XR (methylphenidate hydrochloride) CII for extended-release oral suspension is now available in the U.S. for the treatment of attention deficit hyperactivity disorder (ADHD).

16 Jan 2013

Low birth weight does not increase risk of asthma in young children

Asthma is a serious condition that affects more than 25.7 million Americans, and is responsible for nearly 4,000 deaths annually. While the cause of asthma remains unknown, a study released today in the January issue of Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), has concluded that low birth weight is not associated with asthma risk in young children.

16 Jan 2013

Children with chronic medical conditions more likely to use alternative medicine

Children who regularly see specialists for chronic medical conditions are also using complementary medicine at a high rate, demonstrates recently published research from the University of Alberta and the University of Ottawa.

15 Jan 2013

Obese youngsters at far greater risk than had been supposed

While a great deal of research on childhood obesity has spotlighted the long-term health problems that emerge in adulthood, a new UCLA study focuses on the condition's immediate consequences and shows that obese youngsters are at far greater risk than had been supposed.

15 Jan 2013

Less than 45% of children are vaccinated against flu: Study

This year's flu season is in full swing with 41 states now reporting widespread illness. Unfortunately, not enough children are getting the flu shot even though health officials recommend that all children 6 months and older get the vaccine. According to a new study by researchers at Wake Forest Baptist Medical Center, less than 45 percent of children were vaccinated against the flu during a five-year study period.

11 Jan 2013

BGI-Shenzhen, CHOP to collaborate on research into pediatric brain tumors

The Children's Hospital of Philadelphia (CHOP) and BGI-Shenzhen today announced a formal agreement to collaborate on research into next-generation sequencing and analysis of pediatric brain tumors, in support of the Childhood Brain Tumor Tissue Consortium (CBTTC).

11 Jan 2013