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Transplantation of spermatogonial stem cells isolated from leukemic mice restores fertility without inducing leukemia

While more than 70% of patients survive childhood leukemia, curative chemotherapy can often irreversibly impair the formation of spermatozoa, causing infertility in males.

16 Jun 2005

Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

Disruption of proteins expressed at the junctures between cells (known as tight junctions) is a hallmark of cancer cell invasion and spread (metastasis).

16 Jun 2005

Fine tuning drug levels in neuroblastoma patients is effective

Monitoring and fine tuning the levels of the cancer drug topotecan in children with neuroblastoma holds promise for maximizing the drug's effectiveness while reducing its toxicity, according to investigators at St. Jude Children's Research Hospital.

16 Jun 2005

MRI measurement of breast tumor volume predicts whether a patient's cancer will return

The study, performed at the University of California-San Francisco, of 58 breast cancer patients found that the best way to predict a patient's recurrence-free survival is to review the initial MR examination (before the patient has chemotherapy) and the final MR examination (after chemotherapy has been completed).

16 Jun 2005

Inactive gene may explain higher incidence of prostate cancer in African-Americans compared to Caucasians

Among African-Americans with prostate cancer, a tumor-suppressing gene called GSTP1 is inactivated at a rate 3.5 times higher than among Caucasians, according to a study conducted at the San Francisco VA Medical Center (SFVAMC).

16 Jun 2005

People who have had a minor stroke have a 43% chance of another stroke or vascular event within 10-years

Although worldwide fatality rates from cerebrovascular disease have fallen, stroke remains one of the most serious neurological problems, and leaves many patients with a chronic disability.

16 Jun 2005

Single course of one antibiotic can successfully treat elephantiasis

A single course of one antibiotic can successfully treat elephantiasis (filariasis) - a parasitic worm disease that is one of the most common causes of global disability, concludes a study published in this week’s issue of The Lancet.

16 Jun 2005

Planned home births a safe otption shows finds new study

Planned home births for low risk women in the United States are associated with similar safety and less medical intervention as low risk hospital births, finds a study in this week’s BMJ.

16 Jun 2005

People with a history of epilepsy are at increased risk of developing schizophrenia

The study involved 2.27 million people who were born in Denmark between 1950 and 1987, and were identified from national registers. Personal and family histories of epilepsy and psychosis were obtained, and individuals were monitored for up to 25 years.

16 Jun 2005

Study shows fewer Canadian retailers selling cigarettes to youth

For the first time, the Canada's national rates of retailers refusing to sell tobacco products to youth have exceeded the Federal Tobacco Control Strategy's 10-year target objective of 80% or greater.

16 Jun 2005

Indigenous health gap wider in New Zealand

The health gap between Maori and European New Zealanders is wider than that between American Indians and the US majority white population in the United States, a researcher from The University of Auckland has found.

16 Jun 2005

Buprenorphine treatment for opioid addiction shows promise

Patients who receive buprenorphine treatment for opioid addiction in an office-based setting are more likely than those receiving methadone treatment to be young men, new to drug use, and with no history of methadone treatment, Yale School of Medicine researchers report in a study published in Drug and Alcohol Dependence.

16 Jun 2005

Service learning improves the social skills of students with mental impairments

Previous studies on the effectiveness of service learning programs on social skills of students with moderate cognitive impairments were primarily anecdotal.

16 Jun 2005

Chromium picolinate significantly reduces weight gain associated with common antidiabetic medication

...according to a study released today. Researchers at the Pennington Biomedical Research Center (PBRC), who conducted the study, also found that chromium significantly improved blood sugar control and insulin sensitivity.

16 Jun 2005

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Treating babies who have sickle cell disease (SCD) with oral liquid hydroxyurea appears to prevent the onset of long-term complications triggered by this disease, according to results of a preliminary study by investigators at St. Jude Children's Research Hospital.

16 Jun 2005

Risky sexual behaviour fuelled in gay and bisexual men by the internet

A U.S. study says that gay and bisexual men who use the internet to meet partners are apparently more likely to engage in risky sex but tend to do so with people who have the same HIV status.

16 Jun 2005

Aortic disease difficult to diagnose

Aortic disease kills nearly 15,000 people in the United States each year, but the rarity and complexity of this deadly disorder make accurately diagnosing it difficult for doctors in the health-care trenches, University of Florida researchers have found.

15 Jun 2005

Helicobacter pylori may be linked to atrial fibrillation

A common stomach bug may also be linked to the development of irregular heart rhythm, also known as atrial fibrillation, suggests a small study in Heart

15 Jun 2005

A network of good friends, rather than close family ties, helps you live longer in older age

The research team drew on data from the Australian Longitudinal Study of Aging (ALSA), which began in 1992 in Adelaide, South Australia. The study aimed to assess how economic, social, behavioural and environmental factors affected the health and wellbeing of people aged 70 and upwards.

15 Jun 2005

Drinking soft drinks and other beverages through a properly positioned straw can help to minimize the risk of cavities

Americans drink roughly 576 soft drinks every year - about one and a half cans a day for everyone in the United States. Drinking these beverages places the people who may not follow proper oral hygiene techniques at a higher risk for cavities and other oral health problems.

15 Jun 2005

Drug Trial News

Transplantation of spermatogonial stem cells isolated from leukemic mice restores fertility without inducing leukemia

Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

Fine tuning drug levels in neuroblastoma patients is effective

MRI measurement of breast tumor volume predicts whether a patient's cancer will return

Inactive gene may explain higher incidence of prostate cancer in African-Americans compared to Caucasians

People who have had a minor stroke have a 43% chance of another stroke or vascular event within 10-years

Single course of one antibiotic can successfully treat elephantiasis

Planned home births a safe otption shows finds new study

People with a history of epilepsy are at increased risk of developing schizophrenia

Study shows fewer Canadian retailers selling cigarettes to youth

Indigenous health gap wider in New Zealand

Buprenorphine treatment for opioid addiction shows promise

Service learning improves the social skills of students with mental impairments

Chromium picolinate significantly reduces weight gain associated with common antidiabetic medication

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Risky sexual behaviour fuelled in gay and bisexual men by the internet

Aortic disease difficult to diagnose

Helicobacter pylori may be linked to atrial fibrillation

A network of good friends, rather than close family ties, helps you live longer in older age

Drinking soft drinks and other beverages through a properly positioned straw can help to minimize the risk of cavities

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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