Genomics

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"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

By dissecting the genetic diversity of the most deadly human malaria parasite – Plasmodium falciparum – researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic diversity of the parasite at accelerated time scales.

7 Mar 2024

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

7 Mar 2024

New interdisciplinary center aims to spark developments in synthetic genomics

Applying and developing new technologies for DNA synthesis to pave the way for producing entire artificial genomes - that is the goal of a new interdisciplinary center that is being established at Heidelberg University, Karlsruhe Institute of Technology (KIT), and Johannes Gutenberg University Mainz (JGU). The aim of the Center for Synthetic Genomics is to spark new developments in synthetic genomics through basic research and technology development using methods of artificial intelligence.

6 Mar 2024

Genetic study reveals insights into ancestry-associated differences in type 2 diabetes

The development and progression of type 2 diabetes are affected by numerous biological processes, such as the body's response to insulin, the health of insulin-producing pancreatic beta cells, and the functioning of metabolic pathways.

6 Mar 2024

New insights into the evolution of genomic imprinting

Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father.

6 Mar 2024

Key gene found to prevent muscle breakdown in muscular dystrophy

A specific gene may play a key role in new treatments that prevent muscle in the body from breaking down in serious muscle diseases, muscular dystrophies.

6 Mar 2024

MGI Tech and Eurofins Genomics Partner to Elevate Precision Health with Revolutionary DNBSEQ-T20×2 Sequencer and Related Technologies

MGI Tech, a company committed to building core tools and technology to lead life science, today proudly announced a milestone collaboration with Eurofins Genomics Europe Genotyping A/S (“Eurofins Genomics”), which has placed a corporate order of the revolutionary DNBSEQ-T20×2 (“T20”) ultra-high throughput sequencer, along with the genomics data center ZTRON Appliance and a range of MGI’s state-of-the-art laboratory automation products and systems.

From MGI 6 Mar 2024

Harvard's Catherine Brownstein's Multi-Omics Approach: A New Horizon for Understanding Rare Pediatric Disorders

Catherine Brownstein, MPH, PhD, an esteemed Assistant Professor at Harvard Medical School and an investigator at Boston Children's Hospital.

From Society for Laboratory Automation and Screening (SLAS) 6 Mar 2024

Novel screening system reveals sperm cell development and health at the molecular level

A novel screening system developed at Kyoto University enables researchers to investigate sperm cell development and health at the molecular level.

5 Mar 2024

Unlocking the role of lncREST RNA in DNA replication and repair

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division.

4 Mar 2024

RAD51 protein identified as a key player in preventing DNA re-replication

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent.

4 Mar 2024

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design strategies for controlling cell behavior.

4 Mar 2024

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease. This new tool enables the investigation of thousands of DNA mutations identified by genetic studies in one experiment, guiding the development of advanced diagnostics and treatments.

4 Mar 2024

New ISS investigation expands genes in space toolkit for student spaceflight experiments

For nearly a decade, Genes in Space™ has challenged students to develop spaceflight experiments that use biotechnology to address spaceflight challenges.

4 Mar 2024

Prioritizing biologically motivated approaches in Mendelian randomization studies

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease.

1 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses.

1 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Newly identified Enterococcus species shed light on antibiotic resistance spread

Antibiotic-resistant infection is projected to catch up to cancer as the leading cause of death by 2050, making understanding and limiting the spread of antibiotic-resistant bacteria a priority worldwide.

29 Feb 2024

Scripps Research scientists uncover plausible pathway for protocell formation

Roughly 4 billion years ago, Earth was developing conditions suitable for life. Origin-of-life scientists often wonder if the type of chemistry found on the early Earth was similar to what life requires today.

29 Feb 2024

Genomics

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

New interdisciplinary center aims to spark developments in synthetic genomics

Genetic study reveals insights into ancestry-associated differences in type 2 diabetes

New insights into the evolution of genomic imprinting

Key gene found to prevent muscle breakdown in muscular dystrophy

MGI Tech and Eurofins Genomics Partner to Elevate Precision Health with Revolutionary DNBSEQ-T20×2 Sequencer and Related Technologies

Harvard's Catherine Brownstein's Multi-Omics Approach: A New Horizon for Understanding Rare Pediatric Disorders

Novel screening system reveals sperm cell development and health at the molecular level

Unlocking the role of lncREST RNA in DNA replication and repair

RAD51 protein identified as a key player in preventing DNA re-replication

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

New ISS investigation expands genes in space toolkit for student spaceflight experiments

Prioritizing biologically motivated approaches in Mendelian randomization studies

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Exploring the epigenetic impact of smoking across racial and ethnic groups

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Newly identified Enterococcus species shed light on antibiotic resistance spread

Scripps Research scientists uncover plausible pathway for protocell formation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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