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Past experience alters the brain circuitry responsible for object recognition

Past experience alters the brain circuitry responsible for object recognition

New research from the University of Guelph on the brain and memory could help in developing therapies for people with schizophrenia and Alzheimer's disease. [More]
Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Renal cell carcinoma can sometimes spread to the inferior vena cava (IVC), the body's largest vein, posing a threat to the heart and brain. Robotic nephrectomy for inferior vena cava tumor thrombus has favorable outcomes in selected patients compared with open surgery, which can have a high rate of complications, report surgeons in The Journal of Urology. [More]
Findings may help states optimize tobacco cessation, cancer control programs

Findings may help states optimize tobacco cessation, cancer control programs

A new analysis indicates that states' Web-based and phone-based tobacco cessation programs can help people quit smoking, but certain personal characteristics may lead individuals to prefer one type of program over the other. [More]
Researchers reveal direct link between Wbp2 gene and progressive hearing loss

Researchers reveal direct link between Wbp2 gene and progressive hearing loss

Researchers at King's College London and the Wellcome Trust Sanger Institute in the United Kingdom have for the first time demonstrated a direct link between the Wbp2 gene and progressive hearing loss. The scientists report that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse as well as in two clinical cases of children with deafness with no other obvious features. [More]
Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Researchers have new insight into the complex interchange that can raise blood levels of unhealthy lipids, or fat, in type 1 diabetes, and early evidence that a drug under study to block cancer cell growth can restore healthier levels. [More]
Study reveals association between DNA methylation and type 2 diabetes

Study reveals association between DNA methylation and type 2 diabetes

Researchers from the Hospital del Mar Medical Research Institute have found an epigenetic mechanism implicated in the regulation of blood sugar. The study, published in the journal Molecular Human Genetics, reveals that the methylation of the TXNIP gene is associated with diabetes mellitus type 2 and, in particular, average blood glucose levels. [More]
University of Oxford, SomaLogic partner to discover protein biomarkers for clinical diseases and conditions

University of Oxford, SomaLogic partner to discover protein biomarkers for clinical diseases and conditions

The University of Oxford and SomaLogic announced today that they have agreed to undertake a number of collaborative projects that will employ SomaLogic's proprietary SOMAmer reagents and SOMAscan assay technologies to discover and characterize protein biomarkers for a range of clinical diseases and conditions. [More]
Effective treatments for knee instability may help reduce falls in older adults

Effective treatments for knee instability may help reduce falls in older adults

Symptoms of knee instability in older adults may indicate an increased risk of falling and of experiencing the various physical and psychological effects that can result from falling, according to a study published in Arthritis Care & Research, a journal of the American College of Rheumatology. [More]

Hallucinogens may have therapeutic potential against intimate partner violence

Evidence in a study led by researchers at the University of British Columbia along with University of Alabama at Birmingham School of Public Health Associate Professor Peter S. Hendricks, Ph.D., suggests hallucinogens such as psilocybin or LSD may have therapeutic potential for reducing intimate partner violence, or IPV. [More]
FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

FDA clears Sangamo BioSciences' SB-318 IND application for treatment of MPS I

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced that the U.S. Food and Drug Administration has cleared the Company's Investigational New Drug (IND) application for SB-318, a single treatment strategy intended to provide a life-long therapy for Mucopolysaccharidosis Type I (MPS I). [More]
Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

MyoKardia, Inc., a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced the publication of an article in the leading medical journal Science. [More]
Dnurse Glucose Meter and Dnurse app gain CE approval

Dnurse Glucose Meter and Dnurse app gain CE approval

Dnurse Technology has announced today that the Dnurse Glucose Meter and Dnurse app for Android and iOS have gained CE approval. It is the first CE approved smart glucose meter in China. CE (European Conformity) marking has been a mandatory conformity marking for certain products sold within the European Economic Area (EEA) since 1985. [More]
Novel quantitative method may reduce or eliminate need for invasive biopsies

Novel quantitative method may reduce or eliminate need for invasive biopsies

Scientists have identified a quantitative method to measure changes in biomarkers, which may reduce or eliminate the need for invasive biopsies. The method, described in the February 2016 issue of The FASEB Journal uses a novel chimera design of DNA and small DNA with a companion contrast agent to allow antibodies to cross cellular membranes. [More]
New personalized DNA-based digital assay has potential to dramatically impact CML management

New personalized DNA-based digital assay has potential to dramatically impact CML management

The outcomes of chronic myeloid leukemia (CML) have dramatically improved as the result of tyrosine kinase inhibitor (TKI) treatment. Use of a TKI regimen can lower the blood CML biomarker to levels imperceptible by current detection methods. For patients in "molecular remission," however, uncertainties remain regarding whether they will relapse or if treatment should be discontinued. [More]
Loyola offers multidisciplinary digestive health program

Loyola offers multidisciplinary digestive health program

Loyola University Health System now offers a multidisciplinary digestive health program to treat digestive tract and related medical conditions. Bipan Chand, MD, FACS, FASGE, FASMBS, and Neil Gupta, MD, MPH, are co-directors of the new program. [More]
Stopping driving may lead to faster declines in physical and mental health function among older adults

Stopping driving may lead to faster declines in physical and mental health function among older adults

Driving a car is a key factor in independent living and life satisfaction for older adults. In the U.S., driving is considered an important aspect of personal freedom and gives people a sense of control over their lives. Most adults continue to drive as they age--in fact, 81 percent of people aged 65 and older hold a driver's license in this country. [More]
Vacations may lead to extra weight

Vacations may lead to extra weight

A week's vacation may leave many adults with a heavier midsection--extra weight that can hang around even six weeks post-vacation. [More]
Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

More than 15 years ago, David Warshaw, Ph.D., and coworkers discovered the precise malfunction of a specific protein in the heart that leads to hypertrophic cardiomyopathy, a common culprit in cases of sudden death in young athletes. [More]
ADHD increases risk of becoming obese

ADHD increases risk of becoming obese

With the incidence of obesity increasing steadily, much research has been undertaken to try and identify those people who are most likely to become obese so measures can be taken to avoid excessive weight gain, since it is easier to prevent than to reverse. [More]
Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity. [More]
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