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Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective. This phenomenon, called multidrug resistance, leads to tumors that defy treatment. [More]
One-third of US population can't be transported by ambulance to stroke center within one hour

One-third of US population can't be transported by ambulance to stroke center within one hour

One-third of the US population does not have access to a primary stroke center within one hour by ambulance, and even under optimal conditions, a large proportion of the US would be unable to access a stroke center within this window, according to a new study published in the March 4, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Valley Hospital becomes first hospital in New Jersey to use minimally-invasive approach to treat PAD

Valley Hospital becomes first hospital in New Jersey to use minimally-invasive approach to treat PAD

The Valley Hospital today announced it was the first hospital in New Jersey to use a recently approved device to offer a minimally-invasive approach to the treatment of peripheral artery disease (PAD) in the upper leg, a serious and common condition associated with an increased risk for heart attack and stroke. [More]
Duke researchers find major shift in treatments for peripheral artery disease

Duke researchers find major shift in treatments for peripheral artery disease

Federal efforts to curb Medicare costs for unclogging blood vessels in the limbs slowed the growing use of the treatments, but also coincided with a marked increase in doctors using a more expensive approach, according to an analysis by Duke Medicine researchers. [More]
Early symptoms of post-traumatic stress strongly predict later disability in military personnel

Early symptoms of post-traumatic stress strongly predict later disability in military personnel

Evaluating military personnel with blast-related mild traumatic brain injuries, researchers have found that early symptoms of post-traumatic stress, such as anxiety, emotional numbness, flashbacks and irritability, are the strongest predictors of later disability. [More]
New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, heart disease and cancer, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nucleic Acids Research. [More]
Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

A study from researchers at Massachusetts General Hospital and Brigham and Women's Hospital reveals for the first time exactly how mutations associated with the most common form of inherited Alzheimer's disease produce the disorder's devastating effects. [More]
Study highlights how obesity is linked to brain-level molecular changes

Study highlights how obesity is linked to brain-level molecular changes

Researchers at Aalto University and University of Turku have revealed how obesity is associated with altered opioid neurotransmission in the brain. [More]
Researchers discover retina protein crucial for vision

Researchers discover retina protein crucial for vision

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the LSU Health New Orleans Neuroscience Center of Excellence, discovered a protein in the retina that is crucial for vision. The paper reports, for the first time, the key molecular mechanisms leading to visual degeneration and blindness. [More]
Common flame retardants linked to obesity, say UH researchers

Common flame retardants linked to obesity, say UH researchers

Could your electronics be making you fat? According to University of Houston researchers, a common flame retardant used to keep electronics from overheating may be to blame. [More]
New approach could dramatically increase survival rate of cancer patients

New approach could dramatically increase survival rate of cancer patients

Michail Sitkovsky, an immunophysiology expert at Northeastern University, and his research colleagues have made a breakthrough discovery in cancer treatment. The new approach, some 30 years in the making, could dramatically increase the survival rate of patients with cancer, which kills some 8 million people each year. [More]
Study: Omega-3 fatty acids appear to protect heart function among heart attack survivors

Study: Omega-3 fatty acids appear to protect heart function among heart attack survivors

Taking omega-3 fatty acids appeared to lower inflammation and guard against further declines in heart function among recent heart attack survivors already receiving optimal standard care, according to results from a randomized, controlled trial to be presented at the American College of Cardiology's 64th Annual Scientific Session in San Diego. [More]
Oxytocin may be a potential therapeutic target for improving social function in psychiatric disorders

Oxytocin may be a potential therapeutic target for improving social function in psychiatric disorders

Researchers at the Yerkes National Primate Research Center, Emory University, have shown inducing the release of brain oxytocin may be a viable therapeutic option for enhancing social function in psychiatric disorders, including autism spectrum disorders and schizophrenia. [More]
Hazelden Betty Ford Foundation, Cerner partner to elevate care of individuals with addiction disorders

Hazelden Betty Ford Foundation, Cerner partner to elevate care of individuals with addiction disorders

The Hazelden Betty Ford Foundation, the nation's largest nonprofit addiction treatment solutions provider, announced today it has selected leading health IT supplier Cerner Corp. to implement a new electronic health record (EHR) system throughout its organization. [More]
Bayer announces FDA acceptance of BAY 81-8973 BLA for treatment of hemophilia A

Bayer announces FDA acceptance of BAY 81-8973 BLA for treatment of hemophilia A

Bayer HealthCare today announced that the U.S. Food and Drug Administration has accepted the company's Biologics License Application for BAY 81-8973, a recombinant Factor VIII compound. Bayer is seeking FDA approval of the investigational compound, proposed trade name Kovaltry, for the treatment of hemophilia A in children and adults. [More]
Resverlogix, Emerald Logic complete collaborative research program

Resverlogix, Emerald Logic complete collaborative research program

Resverlogix Corp. today announced that it has completed a collaborative research program with Emerald Logic, a leader in quantitative analytics. Using Fast Collective Evolution Technology (FACET), Emerald Logic analyzed Resverlogix's complete clinical dataset including all measurements obtained from each of 798 patients who participated in the Company's Phase 2 clinical trials ASSERT, SUSTAIN and ASSURE. [More]
Mayo Clinic, Gentag partner to develop wearable biosensors for treating obesity, diabetes

Mayo Clinic, Gentag partner to develop wearable biosensors for treating obesity, diabetes

Mayo Clinic and Gentag, Inc. have reached an agreement to develop the next generation of wearable biosensors designed to fight obesity and diabetes. [More]
Diplomat Pharmacy selected to distribute Novartis' COSENTYX (secukinumab)

Diplomat Pharmacy selected to distribute Novartis' COSENTYX (secukinumab)

Diplomat Pharmacy, Inc. has been selected to the Novartis limited-distribution panel to distribute COSENTYX (secukinumab), a drug approved in January by the U.S. Food and Drug Administration to treat adults with moderate-to-severe plaque psoriasis. [More]
Enrollment completed in Pharma Two B's P2B001 Phase IIb study for Parkinson's disease treatment

Enrollment completed in Pharma Two B's P2B001 Phase IIb study for Parkinson's disease treatment

Pharma Two B announced today that enrollment has been completed in the company's Phase IIb study of P2B001 for the treatment of early stage Parkinson's disease. One hundred and forty-nine patients enrolled in the study conducted at 29 clinical sites throughout the US and Israel. [More]
Study demonstrates that activation of cannabinoid CB2 receptors suppresses chronic pain

Study demonstrates that activation of cannabinoid CB2 receptors suppresses chronic pain

Medical marijuana is proliferating across the country due to the ability of cannabis ingestion to treat important clinical problems such as chronic pain. However, negative side effects and the development of tolerance limit the widespread therapeutic use of Δ9-tetrahydrocannabinol (Δ9-THC), the major psychoactive ingredient in cannabis. [More]