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Pica and geophagy far more prevalent in Madagascar

Though it was identified as a disorder as early as the 14th century, pica, or the eating of non-food items, has for years believed to be all but non-existent in a few corners of the globe - a 2006 study that reviewed research on pica found just four regions - the South of South America, Japan, Korea and Madagascar -where the behavior had never been observed.

25 Oct 2012

Thrasos completes $35 Million financing for development of THR-184 against AKI

Thrasos Therapeutics announced that it has completed a $35 Million (U.S.) financing for the development of THR-184, its lead product candidate for the treatment of acute kidney injury (AKI).

25 Oct 2012

Aspirin therapy can extend life of colorectal cancer patients with PIK3CA mutation

Aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation, Dana-Farber Cancer Institute scientists report in the Oct. 25 issue of the New England Journal of Medicine.

25 Oct 2012

Study indicates that Firemaster 550 is an endocrine disruptor

The flame-retardant mixture known as "Firemaster 550" is an endocrine disruptor that causes extreme weight gain, early onset of puberty and cardiovascular health effects in lab animals, according to a new study spearheaded by researchers from North Carolina State University and Duke University.

25 Oct 2012

Kessler Foundation expert to study effects of prism adaptation therapy for spatial neglect

A.M. Barrett, MD, of Kessler Foundation received a grant totaling $595,756 to study the effects of prism adaptation therapy for spatial neglect in survivors of right-sided stroke.

25 Oct 2012

Maternal mental health important to successful motherhood but overlooked

In the Huffington Post's "Global Motherhood" blog, Christy Turlington Burns, founder of Every Mother Counts, writes, "On the list of health risks women are subjected to, mental health seldom reaches the top. And while there are a lot of stigmas around many diseases, there may not be a close rival to the stigma those with diseases of the mind face each day. Mental illness pushes those who are already marginalized in developed and developing societies, even further into the margins."

25 Oct 2012

Mesh-covered stent improves restoration of blood flow after PCI in heart attack patients

A clinical trial found that the use of a next generation, micronet, mesh-covered stent demonstrated improved restoration of blood flow to heart tissue, compared to the use of either bare-metal or drug-eluting stents in heart attack patients undergoing angioplasty.

25 Oct 2012

Pomc gene can be turned on and off in a mouse model of obesity

Obesity is a chronic metabolic disorder that affects half a billion people worldwide. Managing obesity is difficult, as many patients rebound to their pre-treatment weight. There is a hypothesis that chronic weight gain causes the body to adopt a state that supports excess weight.

25 Oct 2012

Study confirms Elf5 protein as tumor suppressor of breast cancer

A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton University and highlighted as the cover paper in November issue of Nature Cell Biology.

25 Oct 2012

Four-point plan to improve palliative care discussions

In an editorial appearing in the October 25 issue of The New England Journal of Medicine, medical oncologists at Johns Hopkins and Brigham and Women's hospitals provide a four-point plan for integrating palliative care discussions throughout the treatment of patients with terminal illnesses.

25 Oct 2012

Airport security scanners may affect function of insulin pump or CGM devices

Full-body or X-ray scanners used for airport security screening may affect the function of insulin pump or continuous glucose monitoring (CGM) devices.

25 Oct 2012

CINJ makes experts available during National Lung Cancer Awareness Month

According to the American Cancer Society, nearly 6,000 new cases of lung cancer are expected to be diagnosed in New Jersey this year, and 4,200 people will die from the disease.

25 Oct 2012

New findings on how OX40 activation affects T helper cells that target melanoma

Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers-or antigens-on cancer cells and destroy them before they grow into tumors. Cancer cells, for their part, evolve constantly to evade such assassination. Those that succeed become full-blown malignancies. Yet, given the right sort of help, the immune system can destroy even these entrenched tumors.

25 Oct 2012

BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia

BioLineRx, a biopharmaceutical development company, announced today that it intends to conduct an interim analysis of the Phase II/III CLARITY trial of BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia.

25 Oct 2012

Study sheds light on why the weight inevitably comes back

Joint research between the University of Michigan and the Argentina-based National Council of Science and Technology (CONICET) has shed light on one of the most frustrating mysteries of weight loss - why the weight inevitably comes back.

25 Oct 2012

Vascular endothelial cells play a larger role in pulmonary hypertension

It turns out the muscle cells on the outside of blood vessels have been wrongly accused for instigating lung disease. New research shows that while these muscle cells are responsible for constricting or dilating the blood vessels, they are not responsible for sensing the amount of oxygen that gets to the lungs. That message comes from the endothelial cells - special cells that line the blood vessels - along a "signalling pathway."

25 Oct 2012