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New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.

11 Oct 2012

NCI identifies method by which cancerous mRNA escapes the body's safeguards

In innumerable spy movies, the hero or a villain imprints a key in clay in order to later make an exact copy. In the body, the clay is messenger RNA, or mRNA, which imprints a gene and transfers the plans to a ribosome, where the mRNA's code is manufactured into a protein - the shady shop where the clay imprint becomes a key.

11 Oct 2012

Fibulin-3 protein may help identify mesothelioma in early stages

Researchers at NYU School of Medicine have discovered the protein product of a little-known gene may one day prove useful in identifying and monitoring the development of mesothelioma in early stages, when aggressive treatment can have an impact on the progression of disease and patient prognosis.

11 Oct 2012

Checklists can be valid tools in identifying work-related risk factors for musculoskeletal injuries

A new paper by Thomas J. Albin, PE, CPE, of High Plains Engineering Services in Minneapolis, Minnesota, USA, confirms that observational assessment tools, often called checklists, used to assess risk factors such as wrist extension and motion repetition, can be valid tools in identifying work-related risk factors for musculoskeletal injuries.

11 Oct 2012

TSRI scientists identify new gene variants closely associated with bipolar disorder

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified small variations in a number of genes that are closely linked to an increased risk of bipolar disorder, a mental illness that affects nearly six million Americans, according to the National Institute of Mental Health.

11 Oct 2012

Study provides new information on impact of cognitive impairments on MS

Researchers at Trinity College Dublin in collaboration with colleagues in the Department of Neurology at St Vincent's University Hospital and University College Dublin have recently reported new insights into cognitive changes in multiple sclerosis, using newly developed signal processing methods.

11 Oct 2012

Researchers identify astrocytes as new target for Alzheimer's

Alzheimer's disease is a severe neurodegenerative disease that affects 45% of people over 85 years of age. The research teams of Prof. Jin-Moo Lee at Washington University in Saint Louis, USA, and Prof. Milos Pekny at Sahlgrenska Academy in Gothenburg, Sweden, have identified astrocytes as a novel target for the development of future treatment strategies. The results have just been published in the FASEB Journal.

10 Oct 2012

Tips to check for skin cancer

Skin cancer is the most common cancer in the United States and finding spots that could be cancerous is as simple as looking at your skin. Now a new video, "Skin Self-Exam: How to Do," from the American Academy of Dermatology demonstrates how to check your skin and what to look for.

10 Oct 2012

NewLink Genetics to launch algenpantucel-L Phase 3 study in pancreatic cancer

NewLink Genetics Corporation announces launching of an open-label, randomized, multi-institutional Phase 3 study in patients with borderline resectable or locally advanced unresectable pancreatic cancer.

10 Oct 2012

People with diabetic foot ulcers more likely to die prematurely

People with diabetes who develop foot ulcers are at more risk of dying prematurely than those without the complication, finds a new large-scale study. The researchers say the findings highlight the potential need for improved detection and management of those with diabetes and foot ulcers.

10 Oct 2012

HbA1c converter tool launched by NPS

NPS MedicineWise has launched a new online HbA1c converter tool to help people with diabetes understand changes to the way their HbA1c test results are reported in Australia.

10 Oct 2012

Spanish and British scientists design new blood test to identify aggressive prostate cancer

Scientists from the Spanish National Cancer Research Centre (CNIO) in Madrid, along with British colleagues from the Institute for Cancer Research (ICR) and the Royal Marsden NHS Foundation Trust, have developed a test that studies genetic patterns in blood cells to detect advanced-stage prostate cancer.

10 Oct 2012

Scientists discover mechanism used by A20 protein to combat inflammation

Scientists affiliated with VIB and UGent have discovered a mechanism used by the protein A20 to combat inflammation. This could be a very important point of focus in the search for a treatment for autoimmune diseases such as Rheumatoid Arthritis, in which the patient suffers from chronic, uncontrolled inflammation.

10 Oct 2012

Physical activity associated with increased risk of bleeding in children with hemophilia

Hemophilia is a bleeding disorder that, if untreated, causes recurrent bleeding into joints. "Vigorous physical activity is thought to increase risk of bleeds in children with hemophilia, but the magnitude of the risk is unknown," according to background information in the article. Information about risks associated with physical activity is needed to help inform decisions regarding participation in physical activity, the authors write.

10 Oct 2012

Dieting, exercise can spur HDL cholesterol production in type 2 diabetics

With a little exercise and dieting, overweight people with type 2 diabetes can still train their fat cells to produce a hormone believed to spur HDL cholesterol production, report medical researchers from The Methodist Hospital and eight other institutions in an upcoming issue of the Journal of Lipid Research.

10 Oct 2012

Romney's pre-existing conditions plan questioned

News outlets examine this aspect of GOP presidential candidate Mitt Romney's health care policies and report that it would only help a fraction of the country's uninsured.

10 Oct 2012

Nearly all groups of patients with spinal stenosis do better with surgery

Nearly all groups of patients with spinal stenosis—but not smokers—do better with surgery than with nonsurgical treatment, reports a study in the October 1 issue of Spine.

10 Oct 2012

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10 issue of JAMA.

10 Oct 2012

Decrease in doctor appointments, preventable hospital visits draw scrutiny

Medpage Today offers a pair of stories exploring Census findings regarding doctor visits in 2010 as well as MedPAC's interest in "preventable" hospital visits.

10 Oct 2012

High-fat Western diet could lead to development of atherosclerosis

Columbia University Medical Center (CUMC) researchers have found that a diet high in saturated fat raises levels of endothelial lipase (EL), an enzyme associated with the development of atherosclerosis, and, conversely, that a diet high in omega-3 polyunsaturated fat lowers levels of this enzyme.

10 Oct 2012