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Study demonstrates safety and efficacy of NeuroPace RNS System in adults with intractable seizures

Researchers present the findings from a 2-year multicenter randomized double blinded controlled clinical study and a 7 year long-term treatment study of the NeuroPace RNS System at the American Epilepsy Society's 67th Annual Meeting.

9 Dec 2013

Angioplasty may not provide additional benefits compared to drug therapy for patients with stable CAD

For patients with stable coronary artery disease (CAD) who are not experiencing a heart attack and an abnormal stress test, treatment of their narrowed arteries by the common procedure of angioplasty may not provide additional benefits compared to drug therapy alone.

9 Dec 2013

Scientists identify important new genes for epilepsy

Scientists screening the DNA of large cohorts for known and suspected epilepsy associated genes are finding that, while some genes are implicated in discrete phenotypes or forms of epilepsy, other genes are implicated in a wider range of phenotypes. Although ion channel genes are a common cause of epilepsy, the researchers also report a significant number of epilepsy patients with mutations in non-ion channel genes. The studies have important implications for treatment, prognosis and risk counseling.

9 Dec 2013

Study: Uncontrolled epilepsy associated with higher healthcare utilization

Seizures in people with epilepsy are commonly treated with anti-epileptic drugs (AEDs) but 30-40 percent do not achieve adequate seizure control, predisposing them to severe health risks, impaired quality of life and higher healthcare costs.

9 Dec 2013

Underlying loss of awareness during partial seizures is same as deep sleep

Epilepsy patients with complex partial seizures have impaired consciousness during seizure episodes and typically have no memory of the event. However, the mechanisms of seizure unconsciousness are unclear.

9 Dec 2013

Bortezomib reduces GVHD, boosts survival for patients receiving stem-cell transplants

Adding bortezomib (Velcade) to standard preventive therapy for graft-versus-host-disease (GVHD) results in improved outcomes for patients receiving stem-cell transplants from mismatched and unrelated donors, according to researchers from Dana-Farber Cancer Institute.

9 Dec 2013

Study helps explain why survival gap persists for African-Americans with head and neck cancer

A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.

9 Dec 2013

High frequency cell phone users have lower GPA, higher anxiety, and lower happiness in life

Today, smartphones are central to college students' lives, keeping them constantly connected with friends, family and the Internet. Students' cell phones are rarely out of reach whether the setting is a college classroom, library, recreational center, cafeteria or dorm room.

9 Dec 2013

Increased levels of protein HSET linked with worse breast cancer outcomes in African-Americans

Among African-American women with breast cancer, increased levels of the protein HSET were associated with worse breast cancer outcomes, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

UCSF awarded $9.45M federal grant to transform, revolutionize treatment of prostate cancer

UC San Francisco has been awarded a major federal grant to "transform and revolutionize" the treatment of prostate cancer, the second most common form of cancer among American men.

9 Dec 2013

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain.

9 Dec 2013

Downregulation of caveolin-1 contributes to synaptic plasticity deficit in hippocampus of aged rats

Caveolin-1 may be a new target for interfering with age-dependent decline in synaptic plasticity. To explore the relationship between synaptic plasticity in the aging process and changes in learning and memory, Dr. Yang Liu and coworkers from the First Affiliated Hospital, Dalian Medical University, China examined synaptophysin expression in the hippocampus, cortex and cerebellum of rats at different ages, and analyzed the association between synaptophysin expression and cognition and behaviors.

9 Dec 2013

Researchers identify mechanism implicated in brain cancer and drug that decreases brain tumor growth

Researchers at the University of Calgary's Hotchkiss Brain Institute (HBI) have made a discovery that could lead to better treatment for patients suffering from brain cancer.

9 Dec 2013

NIH scientists film early concussion damage and describe brain's response to injury

There is more than meets the eye following even a mild traumatic brain injury. While the brain may appear to be intact, new findings reported in Nature suggest that the brain's protective coverings may feel the brunt of the impact.

9 Dec 2013

Decreased bacterial diversity in gut linked with CRC risk

Decreased diversity in the microbial community found in the human gut is associated with colorectal cancer, according to a new study published December 6 in the Journal of the National Cancer Institute.

9 Dec 2013

Gene discovered to play a part in one per cent of all cancers

Researchers have identified a gene that drives the development of tumours in over one per cent of all cancer patients. This is the first time that the gene CUX1 has been broadly linked to cancer development.

9 Dec 2013

Scientists identify gene encoding hormone to treat heart diseases

Scientists at A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cellular Biology (IMCB) have identified a gene encoding a hormone that could potentially be used as a therapeutic molecule to treat heart diseases.

9 Dec 2013

Study: Ethnic groups with high prevalence of diabetes have high hepatocellular carcinoma rates

Diabetes was associated with an increased risk for developing a type of liver cancer called hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Study provides possible therapeutic strategy for Alzheimer's disease via progesterone

Steroid hormones and their metabolites within the central nervous system are commonly defined as neuroactive steroids or neurosteroids. Although neuroactive steroids have been shown to improve learning and memory ability and protect against amyloid beta peptide-induced neurotoxicity, changes in their level during Alzheimer's disease and their role in Aβ-mediated cognitive impairment remain elusive given the limitation in sample sizes and analysis methods.

8 Dec 2013

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Researchers have caught a protein they previously implicated in a variety of cancer-promoting roles performing a vital function in cell division, survival and development of brain tumors.

8 Dec 2013

Medical Condition News

Study demonstrates safety and efficacy of NeuroPace RNS System in adults with intractable seizures

Angioplasty may not provide additional benefits compared to drug therapy for patients with stable CAD

Scientists identify important new genes for epilepsy

Study: Uncontrolled epilepsy associated with higher healthcare utilization

Underlying loss of awareness during partial seizures is same as deep sleep

Bortezomib reduces GVHD, boosts survival for patients receiving stem-cell transplants

Study helps explain why survival gap persists for African-Americans with head and neck cancer

High frequency cell phone users have lower GPA, higher anxiety, and lower happiness in life

Increased levels of protein HSET linked with worse breast cancer outcomes in African-Americans

UCSF awarded $9.45M federal grant to transform, revolutionize treatment of prostate cancer

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Downregulation of caveolin-1 contributes to synaptic plasticity deficit in hippocampus of aged rats

Researchers identify mechanism implicated in brain cancer and drug that decreases brain tumor growth

NIH scientists film early concussion damage and describe brain's response to injury

Decreased bacterial diversity in gut linked with CRC risk

Gene discovered to play a part in one per cent of all cancers

Scientists identify gene encoding hormone to treat heart diseases

Study: Ethnic groups with high prevalence of diabetes have high hepatocellular carcinoma rates

Study provides possible therapeutic strategy for Alzheimer's disease via progesterone

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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