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Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Idera Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing a novel therapeutic approach for the treatment of autoimmune diseases and genetically defined forms of B-cell lymphoma, today announced that enrollment is open for a Phase 1/2 clinical trial of IMO-8400 in patients with Waldenström's macroglobulinemia, following acceptance of its Investigational New Drug application by the U.S. Food and Drug Administration.

5 Dec 2013

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

A new study shows that poor sleep quality is strongly associated with mood disturbance and lower quality of life among people with extreme obesity.

5 Dec 2013

New research offers fresh insights to drug designers searching for better pain treatments

In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.

5 Dec 2013

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Mothers - but not fathers - exhibited symptoms of depression and experienced declines in overall health after the death of an adult son, while the death of a daughter had no such effect on either parent, according to one of the first studies to examine the impacts of the death of an adult child on parents aged 65 and older.

5 Dec 2013

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fari-as' team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein -a sub-unit of the APC/C complex, involved in the control of cell division-prevents cellular proliferation of rapidly dividing cells.

5 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Researchers discover how PC7 protein affects certain types of cognitive performance

A team of Montr-al researchers at the IRCM led by Dr. Nabil G. Seidah, in collaboration with Dr. William C. Wetsel's team at Duke University in the United States, discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory. Their results, recently published in the scientific journals Proceedings of the National Academy of Sciences (PNAS) and Nature, could have a significant impact on regulating behaviour related to anxiety disorders and trauma.

4 Dec 2013

Roche signs research collaboration and licensing agreement with Molecular Partners

Roche and Molecular Partners AG today announced that they have entered into a research collaboration and licensing agreement to discover, develop and commercialize several proprietary therapeutics incorporating Molecular Partners' DARPin biologics conjugated to toxic agents developed at Roche for the treatment of cancer.

4 Dec 2013

FDA accepts ARCA biopharma's Gencaro IND application for atrial fibrillation

ARCA biopharma, Inc., a biopharmaceutical company developing genetically-targeted therapies for cardiovascular diseases, today announced that the Company's Gencaro Investigational New Drug application for atrial fibrillation has been accepted by the U.S. Food and Drug Administration and is now active.

4 Dec 2013

Health Media Network, Digital Blue Dog partner to create Oncology point-of-care network in the U.S.

Connecticut-based Health Media Network and Florida-based Digital Blue Dog have signed an agreement to exclusively represent DBD's Oncology Network, creating the largest Oncology specific and patient-centric point-of-care network in the U.S.

4 Dec 2013

Novel battery jolts dangerously misbehaving heart back to normal rhythm

The engineering feat that enables a device to jolt a dangerously misbehaving heart back to its normal rhythm and save millions of lives is featured in a new video from the popular Prized Science series from the American Chemical Society (ACS).

4 Dec 2013

Researchers analyze protective effects of mild hypothermia on CNS injuries

There are few data on the effectiveness and mechanism underlying mild hypothermia in the treatment of central nervous system injuries. Therefore, there is a need to investigate the potentially beneficial effects of mild hypothermia on central nervous system injuries.

4 Dec 2013

Direct radiographic imaging reveals negative impact of adiposity in older men and women

Researchers at the National Institute for Aging are working to improve understanding about obesity and cancer. A study, published today in the journal Applied Physiology, Nutrition, and Metabolism, is the first to use direct radiographic imaging of adipose tissue rather than estimates like body mass index (BMI) or waist circumference, and focuses on the relationship between obesity and cancer risk in aging populations. Findings emphasize the negative impact of adiposity on long term health particularly for older men and women.

4 Dec 2013

Sympathetic skin response test assesses autonomic nerve functions in patients with spinal cord injury

Neurological functions following spinal cord injury have generally been assessed using the American Spinal Injury Association (ASIA) impairment scale.

4 Dec 2013

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Los Angeles residents Selim Zilkha and Mary Hayley are raising the stakes in the fight against Alzheimer's disease, the only cause of death among the top 10 in the United States that cannot currently be prevented, cured or slowed.

4 Dec 2013

Study sheds new light on neuropsychiatric disorders

Trauma can scar people so indelibly that their children are affected. History provides examples of generations traumatized by war and starvation, whose children experience altered physiology.

4 Dec 2013

"Appearance exposure" on Internet linked to body image disturbance among adolescent girls

"Appearance exposure" on the Internet has been linked to body image disturbance among adolescent girls. A new study that links specific Facebook activities, but not overall Facebook use to body dissatisfaction and a drive for thinness in teen girls is published in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

4 Dec 2013

Western University research points to promising avenue for PTSD treatment

Pioneering research conducted at Western University (London, Canada) points to a promising avenue for the treatment of post-traumatic stress disorder: utilising neurofeedback training to alter the plasticity of brain networks linked to the condition.

4 Dec 2013

Missing inhibitory connection in brain can trigger social phobias

Fear, at the right level, can increase alertness and protect against dangers. Disproportionate fear, on the other hand, can disrupt the sensory perception, be disabling, reduce happiness and therefore become a danger in itself.

4 Dec 2013

Medical Condition News

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

New research offers fresh insights to drug designers searching for better pain treatments

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Researchers discover how PC7 protein affects certain types of cognitive performance

Roche signs research collaboration and licensing agreement with Molecular Partners

FDA accepts ARCA biopharma's Gencaro IND application for atrial fibrillation

Health Media Network, Digital Blue Dog partner to create Oncology point-of-care network in the U.S.

Novel battery jolts dangerously misbehaving heart back to normal rhythm

Researchers analyze protective effects of mild hypothermia on CNS injuries

Direct radiographic imaging reveals negative impact of adiposity in older men and women

Sympathetic skin response test assesses autonomic nerve functions in patients with spinal cord injury

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Study sheds new light on neuropsychiatric disorders

"Appearance exposure" on Internet linked to body image disturbance among adolescent girls

Western University research points to promising avenue for PTSD treatment

Missing inhibitory connection in brain can trigger social phobias

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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