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IOF publishes practical guidelines to help doctors assess patient response to osteoporosis treatment

The International Osteoporosis Foundation (IOF) has published practical guidelines to assist clinicians in assessing treatment efficacy in patients who experience a fracture while on medication for osteoporosis.

1 Sep 2012

Study shows how NCAN gene results in manic symptoms of bipolar disorder

Flying high, or down in the dumps - individuals suffering from bipolar disorder alternate between depressive and manic episodes. Researchers from the University of Bonn and the Central Institute of Mental Health in Mannheim have now discovered, based on patient data and animal models, how the NCAN gene results in the manic symptoms of bipolar disorder. The results have been published in the current issue of "The American Journal of Psychiatry."

1 Sep 2012

Study assesses post-coronary artery bypass graft surgery atrial fibrillation and long-term survival

Atrial fibrillation is a common complication of cardiac surgery, occurring in 10 percent to 40 percent of patients. Recent studies show it to be associated with poorer health following surgery and poorer long-term survival. Furthermore, development of atrial fibrillation after cardiac surgery leads to average additional health care costs of $15,000 to $20,000.

1 Sep 2012

NFAT protein plays a part in development of acute pancreatitis

It is likely that the protein is also highly significant for other inflammatory diseases. The research results have been published in the American journal Gastroenterology.

1 Sep 2012

Sophiris announces data from PRX302 transrectal safety study on Benign Prostatic Hyperplasia

Sophiris Bio Inc. today announced data from its transrectal safety study, in which PRX302, the company's drug candidate for the treatment of Benign Prostatic Hyperplasia (BPH or enlarged prostate), was well tolerated through three months following a transrectal injection.

1 Sep 2012

Boosting immune system can help reduce asthma attacks due to viral infections

Details of a treatment that could help asthmatics fight infections that trigger 80% of asthma attacks, developed by University of Southampton spin-out company Synairgen, will be presented to European respiratory experts on Sunday 2 September.

1 Sep 2012

Exposure to polychlorinated biphenyls could increase risk of asthma symptoms in children

Children who are exposed to polychlorinated biphenyls (PCBs), which were commonly used in a range of industrial products, could be at risk of an increase in asthma symptoms, according to new research.

1 Sep 2012

GenSpera plans to initiate G-202 Phase II trial in prostate cancer

GenSpera, Inc. announced that the Medicines and Healthcare products Regulatory Agency (MHRA) of the United Kingdom (UK) has cleared for initiation a Phase II human clinical trial of its lead compound, G-202, in the treatment of prostate cancer patients who have failed prior hormonal therapy.

1 Sep 2012

MRI detects high prevalence of abnormalities associated with knee osteoarthritis

A study conducted by researchers at Boston University School of Medicine (BUSM) shows that magnetic resonance imaging (MRI) detected a high prevalence of abnormalities associated with knee osteoarthritis in middle-aged and elderly patients that had no evidence of knee osteoarthritis in X-ray images.

1 Sep 2012

Scientists show how pluripotent stem cells mobilize in wounded planarian worms

The skin, the blood, and the lining of the gut-adult stem cells replenish them daily. But stem cells really show off their healing powers in planarians, humble flatworms fabled for their ability to rebuild any missing body part. Just how adult stem cells build the right tissues at the right times and places has remained largely unanswered.

1 Sep 2012

Veterans Affairs San Diego Healthcare System initiates Pathway Fit clinical trial in obesity

Pathway Genomics Corporation, a San Diego-based genetic testing laboratory, has announced a clinical trial with the Veterans Affairs San Diego Healthcare System (VASDHS).

1 Sep 2012

Tandem Diabetes Care announces availability of t:slim Insulin Pump

Tandem Diabetes Care, Inc. announced today that it has started shipping the t:slim Insulin Pump to customers. The t:slim Insulin Pump is the only insulin pump with a touch screen approved by the U.S. Food and Drug Administration.

1 Sep 2012

Dysfunctional RyRs play a role in stress-induced cognitive dysfunction

ARMGO Pharma, Inc., a biopharmaceutical company developing innovative small molecule drugs known as "Rycals™," which act on the ryanodine receptor calcium-release channel (RyR), announced that a study published today in the prestigious scientific journal Cell reveals the underlying role of calcium leak through the RyR as an important contributor to stress-induced cognitive dysfunction.

1 Sep 2012

Researchers define new treatment for potentially fatal lung disease in patients with CVID

A team of researchers at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute defined a new treatment for a potentially fatal lung disease in patients with a primary immunodeficiency known as common variable immunodeficiency (CVID).

1 Sep 2012

Study may spur research into multi-model imaging based biomarker development for AD

Alzheimer's disease (AD) is one of the most common brain disorders, with an estimated 35 million people affected worldwide. In the last decade, research has advanced our understanding of how AD affects the brain. However, diagnosis continues to rely primarily on neuropsychological tests which can only detect the disease after clinical symptoms begin. In a supplement to the Journal of Alzheimer's Disease, investigators report on the development of imaging-based biomarkers that will have an impact on diagnosis before the disease process is set in motion.

31 Aug 2012

Study reports flaws in design, analysis, and interpretation of Lyme disease

Most doctors treat Lyme disease with antibiotics for two to four weeks after diagnosis, but if symptoms persist after that, medical guidelines recommend against antibiotic retreatment. That recommendation may not be warranted. A newly published statistical review of the four studies upon which those guidelines are based reports flaws in design, analysis, and interpretation that call into question the strength of the evidence against retreatment.

31 Aug 2012

Well-known protein plays central role in development of acute pancreatitis

There is now a clear target for the treatment of acute pancreatitis, according to researchers at Lund University in Sweden, who have discovered that a well-known protein plays a central role in the development of the disease. It is likely that the protein is also highly significant for other inflammatory diseases.

31 Aug 2012

VLST, Pfizer enter in-licensing agreement for anti-CD40 monoclonal antibody

VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for cancer and autoimmune and inflammatory disorders, today announced an in-licensing agreement with Pfizer Inc. for an anti-CD40 monoclonal antibody.

31 Aug 2012

Research identifies new pathway to target with anti-inflammatory drugs

Scientists' discovery of an important step in the body's process for healing wounds may lead to a new way of treating inflammation.

31 Aug 2012

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Transition Therapeutics Inc. today announced that its licensing partner, Elan Corporation, plc has commenced a Phase 2, placebo-controlled, safety and efficacy study of oral ELND005 as an adjunctive maintenance treatment in patients with Bipolar I Disorder (BPD 1) to delay the time to occurrence of mood episodes.

31 Aug 2012

Medical Condition News

IOF publishes practical guidelines to help doctors assess patient response to osteoporosis treatment

Study shows how NCAN gene results in manic symptoms of bipolar disorder

Study assesses post-coronary artery bypass graft surgery atrial fibrillation and long-term survival

NFAT protein plays a part in development of acute pancreatitis

Sophiris announces data from PRX302 transrectal safety study on Benign Prostatic Hyperplasia

Boosting immune system can help reduce asthma attacks due to viral infections

Exposure to polychlorinated biphenyls could increase risk of asthma symptoms in children

GenSpera plans to initiate G-202 Phase II trial in prostate cancer

MRI detects high prevalence of abnormalities associated with knee osteoarthritis

Scientists show how pluripotent stem cells mobilize in wounded planarian worms

Veterans Affairs San Diego Healthcare System initiates Pathway Fit clinical trial in obesity

Tandem Diabetes Care announces availability of t:slim Insulin Pump

Dysfunctional RyRs play a role in stress-induced cognitive dysfunction

Researchers define new treatment for potentially fatal lung disease in patients with CVID

Study may spur research into multi-model imaging based biomarker development for AD

Study reports flaws in design, analysis, and interpretation of Lyme disease

Well-known protein plays central role in development of acute pancreatitis

VLST, Pfizer enter in-licensing agreement for anti-CD40 monoclonal antibody

Research identifies new pathway to target with anti-inflammatory drugs

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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