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EC grants marketing authorization for Pfizer’s INLYTA to treat renal cell carcinoma

Pfizer Inc. announced today that the European Commission (EC) has granted marketing authorization for INLYTA (axitinib) for the treatment of adult patients with advanced renal cell carcinoma (RCC), a type of kidney cancer, after failure of prior treatment with sunitinib or a cytokine.

4 Sep 2012

Ultrastable RNA nanoparticles may help treat cancer and viral infections

A new study by University of Kentucky researchers shows promise for developing ultrastable RNA nanoparticles that may help treat cancer and viral infections by regulating cell function and binding to cancers without harming surrounding tissue.

4 Sep 2012

Scientists discover new anti-cancer and anti-metastatic molecule

A new molecule with anti-cancer and anti-metastatic properties has been discovered by teams from CNRS, CEA, the Institut Curie and Inserm, in collaboration with Australian and British researchers.

4 Sep 2012

Meijer offers generic Lipitor for free to help families be heart healthy

In an effort to help families be heart healthy, this week Midwest retailer Meijer began offering the generic substitute for Lipitor (atorvastatin calcium) for free in all 199 Meijer pharmacies.

4 Sep 2012

A-kinase anchoring proteins influence levels of glucose in the body

Scientists from the United States and Sweden have discovered a new control point that could be important as a drug target for the treatment of diabetes and other metabolic diseases.

4 Sep 2012

GE Healthcare introduces KUBio factory

GE Healthcare, the healthcare business of GE, today introduced KUBio, an innovative off-the-shelf, modular factory designed to save manufacturers of biopharmaceuticals both time and money.

4 Sep 2012

Study finds 93% reduction in head injuries related to cycling among Swedish children

Since 1978 the rate of hospitalisations of Swedish children because of head injuries related to cycling has been reduced by 93%. This means that a large number of children, instead of being severely disabled, have been able to live normal lives.

4 Sep 2012

FDA approves Novartis’ Exelon Patch to treat mild to moderate AD

The US Food and Drug Administration has approved a higher dose of Exelon Patch (rivastigmine transdermal system) for the treatment of people with mild to moderate Alzheimer's disease.

4 Sep 2012

Data from ESTEVE’s S1RA E-52862 Phase I trial programme on pain

ESTEVE announces the recent publication of data from the Phase I clinical trial programme of a novel, highly potent and selective, once-daily, S1RA E-52862, developed by the ESTEVE R&D team, in the British Journal of Clinical Pharmacology.

4 Sep 2012

Morphological changes occur rapidly in response to cardiac injury

Cardiac injury leads to significant structural changes in the heart, including enlargement, excess formation of fibrous growth tissue, and abnormalities of the coronary vasculature. While associated factors have been targeted for therapeutic intervention, the results have been conflicting. Most studies have investigated these changes after six days of injury. However, advanced stages of remodeling have already begun by day seven following injury.

4 Sep 2012

Posterior medial cortex more specifically engaged in recall or imagination

You already know it's hard to balance your checkbook while simultaneously reflecting on your past. Now, investigators at the Stanford University School of Medicine - having done the equivalent of wire-tapping a hard-to-reach region of the brain - can tell us how this impasse arises.

4 Sep 2012

People with normal blood sugar range may be at increased risk of brain shrinkage

People whose blood sugar is on the high end of the normal range may be at greater risk of brain shrinkage that occurs with aging and diseases such as dementia, according to new research published in the September 4, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

4 Sep 2012

Adolescents with autism spectrum disorder more likely to be bullied

A study based on information collected from 920 parents suggests an estimated 46.3 percent of adolescents with an autism spectrum disorder were the victims of bullying, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication.

4 Sep 2012

Exposure to perfluorooctanoic acid appears to increase risk of CVD and peripheral arterial disease

Exposure to perfluorooctanoic acid (PFOA), a manmade chemical used in the manufacture of some common household products, appears to be associated with cardiovascular disease and peripheral arterial disease in a study of 1,216 individuals, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.

4 Sep 2012

Infliximab may offer new hope for people with difficult-to-treat depression

Researchers at Emory University have found that a medication that inhibits inflammation may offer new hope for people with difficult-to-treat depression. The study was published Sept. 3 in the online version of Archives of General Psychiatry.

4 Sep 2012

Plain cigarette packaging likely to reduce appeal of smoking for young people

While Australia has recently passed legislation to ban logos from cigarette packages and to make plain packaging mandatory, other countries are still considering whether or not to take similar measures. New research published in Biomed Central's open access journal BMC Public Health provides a report on the appeal of plain cigarette packs, compared to branded packs, among women in Brazil, and finds that plain packs reduce the appeal of their contents.

4 Sep 2012

PRISM technique as accurate as ELISAs in identifying proteins within biological samples

Combining two well-established analytic techniques and adding a twist identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online.

4 Sep 2012

Parkinson disease may share common pathogenic mechanisms with some cancers

A study that used a Utah genealogic database and a statewide cancer registry to examine the relationship between Parkinson disease (PD) and cancer suggests an increased risk of prostate cancer and melanoma in patients with PD and their relatives, according to a report published Online First by Archives of Neurology, a JAMA Network publication.

4 Sep 2012

Nottingham scientists develop novel antimicrobial catheter

A novel antimicrobial catheter that remains infection-free for up to twelve weeks could dramatically improve the lives of long-term catheter users. The scientists who have developed the new technology are presenting their work at the Society for General Microbiology's Autumn Conference at the University of Warwick.

4 Sep 2012

Prenatal exposure to maternal cigarette smoking may promote obesity in adolescents

Prenatal exposure to maternal cigarette smoking appears associated with an increased risk for adolescent obesity, and is possibly related to subtle structural variations in the brain that create a preference for eating fatty foods, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication.

4 Sep 2012