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NeoGenomics introduces new molecular assay that detects SF3B1 gene mutations

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today that it has validated and launched the first molecular assay for clinical use in the United States that detects mutations in the SF3B1 gene (splicing factor 3b, subunit 1).

6 Aug 2012

Nanobiotix, PharmaEngine partner to develop NBTXR3 for cancer

French Nanobiotix S.A. announced today that it entered into a strategic partnership with PharmaEngine, Inc. for the rapid development of NBTXR3, the lead product from the NanoXray pipeline of Nanobiotix.

6 Aug 2012

Nanobiotix, PharmaEngine partner to commercialize NBTXR3 for soft tissue sarcoma

PharmaEngine, Inc. announced today the execution of an exclusive license and collaboration agreement with France-based Nanobiotix S.A. for the development and commercialization of NBTXR3, currently being investigated in a phase I study with soft tissue sarcoma patients.

6 Aug 2012

TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes

TWi Pharmaceuticals, Inc., a specialty pharmaceutical company based in Taiwan, today announced its fully owned subsidiary, TWi Biotechnology, Inc. has completed a multinational phase II dose-ranging study of AC-201, an orally available IL-1 Beta modulator, in 259 patients with type II diabetes uncontrolled on up to three oral medications.

6 Aug 2012

Clovis Oncology, Foundation Medicine enter diagnostic collaboration

Foundation Medicine, Inc. and Clovis Oncology, Inc. announced today that they have entered into a diagnostic collaboration.

6 Aug 2012

Common ragweed may induce airways irritation through terpenoids

Allergy to pollen of common ragweed is increasingly affecting patients and is second only to grass pollen in terms of incidence in the general population of many European countries.

6 Aug 2012

Scientists identify key factor that drives resistance to cancer drug

Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors - such as those of the breast, prostate, lung and colon - that have metastasized, or spread, throughout the body. A team of scientists led by Fred Hutchinson Cancer Research Center has discovered a key factor that drives this drug resistance - information that ultimately may be used to improve the effectiveness of therapy and buy precious time for patients with advanced cancer.

6 Aug 2012

Associate director of Clinical Genetics receives Angelo DiGeorge Medal of Honor

Donna McDonald-McGinn, M.S., CGC, associate director of Clinical Genetics and program director of the "22q and You" Center at The Children's Hospital of Philadelphia, received the Angelo DiGeorge Medal of Honor on July 6 at the 8th Biennial International 22q11.2 DS Conference in Lake Buena Vista, Florida. Ms. McDonald-McGinn, who began her career at CHOP in 1985, is the second person to receive this highly esteemed honor.

6 Aug 2012

Astellas announces closure of Urogenix research facility

Astellas Pharma Inc. announced that it decided to close Urogenix, Inc., an Astellas subsidiary, which is a research facility focusing on drug discovery in the field of urology.

6 Aug 2012

Study focuses on factors related to obesity in nurses with adverse work schedules

For nurses who work long hours or other "adverse work schedules," the risk of obesity is related to lack of opportunity for exercise and sleep, suggests a study in the August issue of Journal of Occupational and Environmental Medicine, the official publication of the American College of Occupational and Environmental Medicine (ACOEM).

6 Aug 2012

Prior contralateral amputation predicts outcomes after LEB for critical limb ischemia

Researchers from the Vascular Study Group of New England (VSGNE) report that prior contralateral amputation predicts worse outcomes for lower extremity bypasses (LEB's) performed in the intact limb.

6 Aug 2012

Computerized brain fitness program improves memory and language skills in older adults

UCLA researchers found that older adults who regularly used a brain fitness program played on a computer demonstrated significantly improved memory and language skills.

6 Aug 2012

New sequencing approach can provide more effective method of BRCA1/2 mutational analysis

Individuals with mutations in BRCA1 and BRCA2 genes have a significantly higher risk of developing breast and ovarian cancers. Families at risk have been seeking genetic testing and counseling based on their mutation carrier status, but the standard method of direct sequencing is labor-intensive, costly, and it only targets a part of the BRCA1 and BRCA2 genes.

6 Aug 2012

Neutrophils play an unexpected role in mediating insulin resistance

Researchers at the University of California, San Diego School of Medicine say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays an unexpected role in mediating insulin resistance - the central characteristic of type 2 diabetes, which afflicts an estimated 26 million Americans.

6 Aug 2012

Researchers make major advance in efforts to regenerate damaged hearts

Researchers have made a major advance in efforts to regenerate damaged hearts. Grafts of human cardiac muscle cells, grown from embryonic stem cells, coupled electrically and contracted synchronously with host muscle following transplantation in guinea pig hearts.

6 Aug 2012

Novartis, Penn partner to study and commercialize novel cellular immunotherapies for cancer

In an alliance aimed at bringing a new, personalized immunotherapy approach to patients with a wide variety of cancers, the University of Pennsylvania and Novartis announced today an exclusive global research and licensing agreement to further study and commercialize novel cellular immunotherapies using chimeric antigen receptor (CAR) technologies.

6 Aug 2012

TAU research identifies protein group that may kick-start allergic reactions

Allergies, or hypersensitivities of the immune system, are more common than ever before. According to the Asthma and Allergies Foundation of America, one in five Americans suffers from an allergy - from milder forms like hay fever to more severe instances, like peanut allergies which can lead to anaphylactic shock.

6 Aug 2012

First generic versions of Singulair receive FDA approval for treatment of asthma, allergies

The U.S. Food and Drug Administration today approved the first generic versions of Singulair (montelukast sodium) for use in adults and children to control asthma symptoms and to help relieve symptoms of indoor and outdoor allergies.

6 Aug 2012

Sanofi-aventis receives FDA approval for Zaltrap to treat colorectal cancer

The U.S. Food and Drug Administration today approved Zaltrap (ziv-aflibercept) for use in combination with a FOLFIRI (folinic acid, fluorouracil and irinotecan) chemotherapy regimen to treat adults with colorectal cancer.

6 Aug 2012

Similar molecular pathways involved in intellectual disability due to Fragile X and Down syndromes

Intellectual disability due to Fragile X and Down syndromes involves similar molecular pathways report researchers in The EMBO Journal. The two disorders share disturbances in the molecular events that regulate the way nerve cells develop dendritic spines, the small extensions found on the surface of nerve cells that are crucial for communication in the brain.

3 Aug 2012

Medical Condition News

NeoGenomics introduces new molecular assay that detects SF3B1 gene mutations

Nanobiotix, PharmaEngine partner to develop NBTXR3 for cancer

Nanobiotix, PharmaEngine partner to commercialize NBTXR3 for soft tissue sarcoma

TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes

Clovis Oncology, Foundation Medicine enter diagnostic collaboration

Common ragweed may induce airways irritation through terpenoids

Scientists identify key factor that drives resistance to cancer drug

Associate director of Clinical Genetics receives Angelo DiGeorge Medal of Honor

Astellas announces closure of Urogenix research facility

Study focuses on factors related to obesity in nurses with adverse work schedules

Prior contralateral amputation predicts outcomes after LEB for critical limb ischemia

Computerized brain fitness program improves memory and language skills in older adults

New sequencing approach can provide more effective method of BRCA1/2 mutational analysis

Neutrophils play an unexpected role in mediating insulin resistance

Researchers make major advance in efforts to regenerate damaged hearts

Novartis, Penn partner to study and commercialize novel cellular immunotherapies for cancer

TAU research identifies protein group that may kick-start allergic reactions

First generic versions of Singulair receive FDA approval for treatment of asthma, allergies

Sanofi-aventis receives FDA approval for Zaltrap to treat colorectal cancer

Similar molecular pathways involved in intellectual disability due to Fragile X and Down syndromes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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