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Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

Allergic reactions trigger changes in brain behavior development in unborn males and females

Researchers at the University of Maryland School of Medicine and colleagues at Ohio State University have discovered that allergic reactions trigger changes in brain behavior development in unborn males and females.

29 Mar 2019

Researchers identify 30 genes associated with schizophrenia

The research group led by Prof. Alex Schier, Director of the University of Basel's Biozentrum, has identified 30 genes associated with schizophrenia.

29 Mar 2019

New migraine-associated mechanism discovered

A mutation in the gen that codes the ionic channel TRESK -involved in the control of neuron irritability- causes the dysfunction of some neurons that increase neuronal activity and induce migraine pain.

29 Mar 2019

Study: Maternal deaths from cesarean sections far higher in low and middle-income countries

Cesarean sections are disproportionately threatening the lives of women and babies in low and middle-income countries, according to a study led by Queen Mary University of London.

29 Mar 2019

Exposure to subtle cues of coffee can arouse our minds, study reveals

Just looking at something that reminds us of coffee can cause our minds to become more alert and attentive, according to a new U of T study.

29 Mar 2019

Study: Seasonal allergies increase when the timing of spring 'greenup' changes

Human-induced climate change is disrupting nature's calendar, including when plants bloom and the spring season starts, and new research from the University of School of Public Health suggests we're increasingly paying the price for it in the form of seasonal allergies.

29 Mar 2019

Researchers discover 'taste bud cells' in mice lungs after severe bout of flu

Most people who weather an infection with influenza fully recover after a week or two. But for some, a severe case of the flu can actually reshape the architecture of their lungs and forever compromise their respiratory function.

29 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

The U.S. Army Medical Research Institute of Infectious Diseases today announced that, for the first time, the U.S. Food and Drug Administration has provided formal regulatory agreement for use of an animal model to support development of a drug candidate, remdesivir, for treating deadly Ebola virus infections.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

Study uncovers details about human immune response to dengue infection

About 40 percent of the global population is at risk for contracting dengue - the most important mosquito-borne viral infection and a close "cousin" of the Zika virus - and yet, no effective treatment or safe licensed vaccine exists.

29 Mar 2019

Dogs could be source of novel human influenza strains, 10-year study suggests

Results from a 10-year study suggest two strains of influenza that could mix and form a dangerous new strain of influenza spread by dogs.

28 Mar 2019

New strategy for potential treatment of HBV associated liver cancer

Researchers from Duke-NUS Medical School, Singapore General Hospital and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma, a commonly occurring liver cancer.

28 Mar 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

Artificial intelligence can predict risk of premature death

Artificial intelligence may significantly improve the accuracy of premature death prediction for patients with chronic disease, compared with standard models.

28 Mar 2019

European Research Council awards grant for research on insulin-producing cells

The ERC Advanced Grant is one of the most prestigious funding programmes for research in Europe. Per-Olof Berggren, professor of experimental endocrinology at Karolinska Institutet, is now awarded this grant for the second time.

28 Mar 2019

Researchers describe mathematical model as key to developing effective drugs for brain disorders

A collaboration between researchers from the UAB Institute of Neurosciences and the pharmaceutical company GlaxoSmithKline, published in March in Trends in Pharmacological Sciences, describes a mathematical model to quantify the activity of biased G-protein-coupled receptors.

28 Mar 2019

Preoperative donor muscle training expedites rehabilitation process in patients

Researchers at the Institute of Cognitive Neuroscience of the Higher School of Economics have proposed to train transplanted muscles in advance with new movements so that the brain can learn to use them more quickly after autotransplantation.

28 Mar 2019

Sepsis research in quest for treatments focuses on role of genes

Scientists say the study could help identify those most vulnerable to sepsis, which kills more than 50,000 people in the UK each year and is the leading preventable cause of death worldwide.

28 Mar 2019