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Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

With drug resistance being on the rise worldwide, bacterial infections pose one of the greatest global threats to human health. By deciphering the host-pathogen interaction on a molecular level, researchers hope to pave the way for new therapies.

10 May 2017

Researchers uncover structure of embryo-protecting protein

Revelations about a protein expressed in fetal cells could provide novel insights into its function and future immunosuppressive therapies.

10 May 2017

Use of postmenopausal hormone therapy may increase risk of hearing loss

Hearing loss afflicts approximately 48 million Americans and the number is expected to increase as the population ages.

10 May 2017

UT Southwestern study sheds light on role of hormone ghrelin in blood glucose control

UT Southwestern research investigating the blood glucose-regulatory actions of the hormone ghrelin may have implications for development of new treatments for diabetes.

10 May 2017

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Primary colorectal tumors secrete VEGF-A, inducing CXCL1 and CXCR2-positive myeloid-derived suppressor cell (MDSC) recruitment at distant sites and establishing niches for future metastases, report Medical University of South Carolina investigators in an article published online ahead of print on April 28, 2017 by Cancer Research.

10 May 2017

Smiling can make people look two years older, study shows

Turn that frown upside-down? Not if you're keen on looking younger, you shouldn't. A new study shows that smiling can make you appear to be two years older than if you wear a poker face.

10 May 2017

Natural compound in grape seed extract could increase strength, life of composite-resin fillings

A natural compound found in grape seed extract could be used to strengthen dentin -- the tissue beneath a tooth's enamel -- and increase the life of resin fillings, according to new research at the University of Illinois at Chicago College of Dentistry.

10 May 2017

Two widely used drugs show effectiveness in treating patients with CRVO-associated macular edema

Monthly eye injections of Avastin (bevacizumab) are as effective as the more expensive drug Eylea (aflibercept) for the treatment of central retinal vein occlusion, according to a clinical trial funded by the National Eye Institute, part of the National Institutes of Health.

10 May 2017

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

A common treatment for asthma, which is the most prevalent chronic childhood disease, requires use of an inhaler. But a big problem with inhalers, used to deliver steroids and other drugs in an aerosol form, is that children often don't operate them properly.

10 May 2017

Most Philadelphia home kitchens contain at least one foodborne pathogen, study finds

If held to the same standards as restaurants in the area, most Philadelphia home kitchens examined for a pair of Drexel University studies would receive "critical code violations."

9 May 2017

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Certain blood vessels in the brainstem constrict when blood vessels elsewhere in the body would dilate. And that contrary behavior is what keeps us breathing, according to a new paper by UConn researchers published May 8 in eLife.

9 May 2017

Study finds high rate of unnecessary antibiotic prescribing for low-risk Ontarian seniors

Nearly one in two seniors in Ontario who visited a family doctor for a non-bacterial infection received an unnecessary antibiotic prescription, according to a new study from the Institute for Clinical Evaluative Sciences Western site in London, Ontario and Lawson Health Research Institute.

9 May 2017

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia into complete initial remission, researchers have now opened a first-in-human clinical trial aimed at reducing the rate of relapse after the therapy, which is about 50 percent.

9 May 2017

Mothers infected with malaria during pregnancy can alter infants’ immunity

Mothers infected with malaria during pregnancy can pass more of their own cells to their baby and change the infant's risk of later infection, a new study shows.

9 May 2017

Low BMI may not be causal risk factor for Alzheimer's disease

A new large-scale genetic study found that low body mass index is likely not a causal risk factor for Alzheimer's disease, as earlier research had suggested, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

9 May 2017

Older adults hospitalized for assault-related injuries more likely to suffer subsequent abuse

Older adults who have been hospitalized for injuries from an assault are more likely to experience subsequent physical abuse if they are female, widowed, diagnosed with dementia, or return home to live with the perpetrator, according to a new study in the Journal of the American Geriatrics Society.

9 May 2017

Studies pave way for genome-targeted treatments in pancreatic cancer

University of Pittsburgh and UPMC researchers are paving the way for genome-targeted treatments in pancreatic cancer, an especially deadly form of cancer with few existing therapeutic options, according to a pair of recent studies.

9 May 2017

Foot pain and posture may play role in recurrent falls among older adults

Researchers from Hebrew Senior Life's Institute for Aging Research have discovered that foot pain - particularly severe foot pain - correlates to a higher incidence of recurrent falls.

9 May 2017

Maternal education can act as 'social vaccine' for childhood malaria infection, study finds

Every two minutes, a child will die from malaria in Africa. It is a preventable, treatable disease, that each year affects approximately 200 million people globally.

9 May 2017

Researchers find many postmarket safety events after FDA approval of new drugs

How often are safety concerns raised about a drug after it's been approved by the FDA? Nicholas Downing, MD, of the Department of Medicine at Brigham and Women's Hospital, and colleagues have found that for drugs approved between 2001 and 2010, nearly 1 in 3 had a postmarket safety event.

9 May 2017

Medical Research News

Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

Researchers uncover structure of embryo-protecting protein

Use of postmenopausal hormone therapy may increase risk of hearing loss

UT Southwestern study sheds light on role of hormone ghrelin in blood glucose control

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Smiling can make people look two years older, study shows

Natural compound in grape seed extract could increase strength, life of composite-resin fillings

Two widely used drugs show effectiveness in treating patients with CRVO-associated macular edema

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

Most Philadelphia home kitchens contain at least one foodborne pathogen, study finds

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Study finds high rate of unnecessary antibiotic prescribing for low-risk Ontarian seniors

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

Mothers infected with malaria during pregnancy can alter infants’ immunity

Low BMI may not be causal risk factor for Alzheimer's disease

Older adults hospitalized for assault-related injuries more likely to suffer subsequent abuse

Studies pave way for genome-targeted treatments in pancreatic cancer

Foot pain and posture may play role in recurrent falls among older adults

Maternal education can act as 'social vaccine' for childhood malaria infection, study finds

Researchers find many postmarket safety events after FDA approval of new drugs

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Expanding research and clinical options for children with cancer

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