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Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

People diagnosed with schizophrenia who are prone to hallucinations are likely to have structural differences in a key region of the brain compared to both healthy individuals and people diagnosed with schizophrenia who do not hallucinate, according to research published today.

17 Nov 2015

Study may lead to development of highly accurate screening test for early-stage ovarian cancer

Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.

17 Nov 2015

Myriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV events in diabetes patients

Myriad RBM, a wholly-owned subsidiary of Myriad Genetics, Inc., today announced that its DiscoveryMAP platform successfully identified combinations of 15 protein biomarkers associated with cardiovascular (CV) events or death in people with pre-diabetes or early type 2 diabetes, according to a study published by the journal Circulation.

17 Nov 2015

Study reveals why colorectal cancer still returns in some patients after treatment

Cetuximab, marketed as Erbitux, is one of the key therapies for metastatic colorectal cancer. Yet the cancer still returns in some patients, shortening overall survival.

17 Nov 2015

Study shows how parasitic worm infection increases susceptibility to TB

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tuberculosis (TB) that the parasite is known to cause.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

Research shows how scientists altered stem cells, triggered bone growth

Imagine you have a bone fracture or a hip replacement, and you need bone to form, but you heal slowly - a common fact of life for older people. Instead of forming bone, you could form fat. Researchers at the University of North Carolina School of Medicine may have found a way to tip the scale in favor of bone formation. They used cytochalasin D, a naturally occurring substance found in mold, as a proxy to alter gene expression in the nuclei of mesenchymal stem cells to force them to become osteoblasts (bone cells).

17 Nov 2015

Sheffield Hallam University awards doctorate to key NHS leader

The Chief Executive of the Sheffield Teaching Hospitals NHS Foundation Trust, Sir Andrew Cash, has been awarded an honorary doctorate from Sheffield Hallam University today.

17 Nov 2015

Scientists show how absence of microbiota has remarkable effect against obesity

In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning of our organs. In particular, microbiota has also an impact on the way calories are absorbed and how fat cells develop.

17 Nov 2015

Researchers identify molecular patterns that dominate gene expression in the human brain

The human brain may be the most complex piece of organized matter in the known universe, but Allen Institute researchers have begun to unravel the genetic code underlying its function. Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

CRI scientists identify emergency blood-formation system inside the body

Scientists at the Children's Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers report that when tissue damage occurs, in times of excessive bleeding, or during pregnancy, a secondary, emergency blood-formation system is activated in the spleen.

17 Nov 2015

Researchers identify new target for novel immune-oncology treatments

By studying a type of immune cells, a team of researchers at the IRCM led by André Veillette, MD, identified the mechanism of action for a new target for novel immune-oncology treatments. Their discovery is published today in the print edition of the scientific journal the Journal of Experimental Medicine.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

17 Nov 2015

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Researchers at the University of Arizona have invented a device that for the first time allows neurosurgeons, who use microscopes extensively while operating, to see blood flowing inside vessels and more clearly distinguish cancerous from healthy tissue under the microscope.

17 Nov 2015

Improved gene therapy treatment shows promise in mice with cystic fibrosis

An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment. Those are the encouraging results of a study presented by the Laboratory for Molecular Virology and Gene Therapy at KU Leuven, Belgium.

17 Nov 2015

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of natural products, which were originally thought to be secondary metabolites of marine sponges only.

17 Nov 2015

MIPT researchers patent graphene biosensors that may accelerate development of novel drugs

The US Patent Office has recently published the patent application (no. US 2015/0301039), which was filed by the MIPT in May this year and is titled Biological Sensor and a Method of the Production of Biological Sensor. In Russia, this development is already protected by the patent No. 2527699 with a priority date of February 20, 2013. The key feature of the sensor is the use of a linking layer for biomolecule immobilization comprising a thin film of graphene or graphene oxide.

17 Nov 2015

Corning signs agreement to become global distributor for popular BioCision products

Corning Incorporated and BioCision, LLC today announced an agreement that will enable laboratories around the world to further standardize and simplify key steps in their cell culture workflow.

17 Nov 2015

Medical Science News

Structural differences in key brain region linked to hallucinations in people diagnosed with schizophrenia

Study may lead to development of highly accurate screening test for early-stage ovarian cancer

Myriad RBM's DiscoveryMAP platform identifies protein biomarkers linked to CV events in diabetes patients

Study reveals why colorectal cancer still returns in some patients after treatment

Study shows how parasitic worm infection increases susceptibility to TB

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Research shows how scientists altered stem cells, triggered bone growth

Sheffield Hallam University awards doctorate to key NHS leader

Scientists show how absence of microbiota has remarkable effect against obesity

Researchers identify molecular patterns that dominate gene expression in the human brain

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

CRI scientists identify emergency blood-formation system inside the body

Researchers identify new target for novel immune-oncology treatments

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Improved gene therapy treatment shows promise in mice with cystic fibrosis

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

MIPT researchers patent graphene biosensors that may accelerate development of novel drugs

Corning signs agreement to become global distributor for popular BioCision products

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