Pharmaceutical News RSS Feed - Pharmaceutical News

Study provides vital information about mechanisms governing DNA repair

Study provides vital information about mechanisms governing DNA repair

DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory of Dr. Hugo Wurtele, a researcher in immunology-oncology at the Maisonneuve-Rosemont Hospital (CIUSS de l'Est-de-l'Île-de-Montréal) and professor at the Faculty of Medicine, University of Montreal, and recently published in the prestigious journal Nucleic Acids Research, provides valuable information about certain mechanisms governing DNA repair. [More]
COG presents plan to effectively handle future pediatric cancer drug shortages

COG presents plan to effectively handle future pediatric cancer drug shortages

The Children's Oncology Group has taken steps to help pediatric oncologists across the United States plan for the next shortage of life-saving chemotherapy drugs used for children with cancer. The COG is the world's largest organization devoted exclusively to childhood and adolescent cancer research and is supported in part by the St. Baldrick's Foundation, the largest private funder of childhood cancer research grants. [More]
U of M's 'Ask About Aspirin' initiative aims to reduce incidence of first heart attack or stroke

U of M's 'Ask About Aspirin' initiative aims to reduce incidence of first heart attack or stroke

Cardiovascular diseases are the leading causes of death and disability in the United States, accounting for nearly one-third of all deaths. The diseases also create an immense national health economic burden. [More]
FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

In laboratory neuronal cultures, an FDA-approved drug used to treat high blood pressure reduced cell damage often linked to Alzheimer's disease, say researchers at Georgetown University Medical Center and the National Institutes of Health. [More]
Sphingosine kinase inhibitor slows castration-resistant prostate cancer cell growth

Sphingosine kinase inhibitor slows castration-resistant prostate cancer cell growth

A first-in-class sphingosine kinase 2 inhibitor slowed the growth of castration-resistant prostate cancer cells, in part by inhibiting the enzyme dihydroceramide desaturase (DEGS), but did not kill them, according to the results of preclinical in vitro and in vivo studies published in the December 2015 issue of Molecular Cancer Therapeutics by researchers at the Medical University of South Carolina and others. [More]
EC approves expanded use of Daklinza (daclatasvir) for patients with chronic HCV and HIV co-infection

EC approves expanded use of Daklinza (daclatasvir) for patients with chronic HCV and HIV co-infection

Bristol-Myers Squibb today announced that the European Commission has approved the expanded use of Daklinza, a first-in-class oral, once-a-day pill used in combination with other treatments as an option for adult patients with chronic hepatitis C virus infection who are co-infected with HIV or who have had a prior liver transplant. [More]
Allergan and AstraZeneca partner to develop, commercialize ATM-AVI for MBL-producing pathogens

Allergan and AstraZeneca partner to develop, commercialize ATM-AVI for MBL-producing pathogens

Allergan plc today announced that it has entered into a global agreement with AstraZeneca to develop and commercialize ATM-AVI, an investigational, fixed-dose antibiotic combining aztreonam and avibactam. [More]
Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Allergan plc., a leading global pharmaceutical company today announced that its Phase III ready investigational medication rapastinel (GLYX-13) received Breakthrough Therapy designation from the U.S. Food and Drug Administration for adjunctive treatment of Major Depressive Disorder (MDD). [More]
Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen. [More]
Access for new melanoma treatment remains uncertain for patients despite UK launch

Access for new melanoma treatment remains uncertain for patients despite UK launch

Novartis announced today that Tafinlar (dabrafenib) + Mekinist (trametinib), the first oral combination therapy to be licensed for advanced melanoma, is now available in the UK for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation. [More]
Researchers develop new painkiller as strong as morphine but not addictive

Researchers develop new painkiller as strong as morphine but not addictive

Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology. [More]
Anticholinergic medications may not be best option for dementia patients in rehab facility

Anticholinergic medications may not be best option for dementia patients in rehab facility

During rehabilitation following an acute hospital stay, medications that block neurotransmitters may be overprescribed to older patients suffering from delirium superimposed on dementia, according to health researchers. [More]
Vitabiotics introduces new Wellkid Multi-vitamin liquid for kids

Vitabiotics introduces new Wellkid Multi-vitamin liquid for kids

New to the Wellkid range, Vitabiotics Wellkid Multi-vitamin liquid includes a range of 15 vitamins and minerals to help maintain all round health, with Swiss Alpine malt. [More]
New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

A new blood clotting analysis system designed in Japan makes it easier to determine the effects of taking one or more antithrombotic (anti-clotting) drugs. [More]
Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

The U.S. Food and Drug Administration today approved Zepatier (elbasvir and grazoprevir) with or without ribavirin for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4 infections in adult patients. [More]
Halaven (eribulin mesylate) approved for treatment of liposarcoma

Halaven (eribulin mesylate) approved for treatment of liposarcoma

The U.S. Food and Drug Administration today approved Halaven (eribulin mesylate), a type of chemotherapy, for the treatment of liposarcoma (a specific type of soft tissue sarcoma) that cannot be removed by surgery (unresectable) or is advanced (metastatic). This treatment is approved for patients who received prior chemotherapy that contained an anthracycline drug. [More]
New breakthrough drug shows promise to fight antibiotic-resistant infections

New breakthrough drug shows promise to fight antibiotic-resistant infections

A New York pharmaceutical company, TGV-Laboratories, has developed a groundbreaking drug that shows promise in treating a wide variety of antibiotic-resistant fungal and bacterial infections. [More]
Using painkillers during pregnancy may harm fertility of daughters

Using painkillers during pregnancy may harm fertility of daughters

Using painkillers in pregnancy may reduce fertility in subsequent generations, research suggests. Tests in rats found that when a mother was given painkillers during pregnancy, her female offspring had fewer eggs, smaller ovaries and smaller litters of babies than those not exposed to the drugs. [More]
Newly drafted consensus statement promotes widespread use of HPV vaccines to prevent cancer

Newly drafted consensus statement promotes widespread use of HPV vaccines to prevent cancer

Leaders of several cancer centers designated by the National Cancer Institute have united to support human papillomavirus vaccination. Among them is Cheryl Willman, MD, Director and CEO of the University of New Mexico Comprehensive Cancer Center. [More]
Study leads to FDA approval of first immunotherapy for treatment of neuroblastoma

Study leads to FDA approval of first immunotherapy for treatment of neuroblastoma

Building upon more than two decades of basic research conducted at Children's Hospital Los Angeles, Araz Marachelian, MD, of CHLA, and her colleagues at pediatric academic centers across the U. S., have shown that an immunotherapy that until now has only been available to patients enrolled in research studies, is equivalent to the product that has been manufactured for commercial use and can be made available to all patients. [More]
Advertisement
Advertisement