Neuroblastoma News and Research

Latest Neuroblastoma News and Research

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Researchers evaluated the relationship between congenital cytomegalovirus (cCMV) infection and acute lymphoblastic leukemia (ALL).

11 Jan 2023

Study shows positive effect of concentrating surgery for children with neuroblastoma

Neuroblastoma is a tumor of the sympathetic nervous system that occurs mainly in young children. Every year, 25 children in the Netherlands receive this diagnosis. Surgery to remove the tumor tissue forms an important part of the treatment plan.

19 Dec 2022

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Lund researchers identify the reason behind chemoresistance in neuroblastoma

Researchers at Lund University in Sweden have identified one of the reasons why the childhood cancer neuroblastoma becomes resistant to chemotherapy.

11 Nov 2022

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to developing cancer.

28 Oct 2022

Salk's three collaborative projects win 2022 Curebound Discovery Grant

The Salk Institute's American Cancer Society Professor Tony Hunter, Professor Reuben Shaw, and Assistant Professor Graham McVicker are among 12 inaugural 2022 Discovery Grant winners.

19 Oct 2022

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

During brain development, neurons have to migrate long distances through complex environments until they reach their final destination.

18 Oct 2022

New combination therapy shows potential to improve survival in children with neuroblastoma

Children who suffer a relapse of the aggressive cancer known as neuroblastoma have small chances of survival.

22 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

CHOP helps launch new computational platform to harmonize pediatric cancer data

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

4 Aug 2022

Novel targeted therapy may be an effective treatment option for neuroblastoma

New research from VCU Massey Cancer Center -; published Thursday in Cell Reports -; demonstrated that a novel targeted therapy could be an effective treatment option for a deadly pediatric cancer known as neuroblastoma.

28 Jul 2022

Phase I clinical trial of new blocking antibody therapy shows promising results for the treatment of advanced medulloblastoma

Effective and safe treatments are needed for medulloblastoma-;the most common type of cancerous brain tumor in children-;especially for patients whose cancer has spread to the spinal cord.

14 Jul 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Study confirms the benefits of 'bridge therapy' for some children with high-risk neuroblastoma

Approximately half of children with neuroblastoma-;a childhood cancer that develops from immature nerve cells-;have a form that indicates a high likelihood of recurrence.

6 Jun 2022

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

Children with high-risk neuroblastoma had worse outcomes if they were from certain racial/ethnic groups or were on public rather than private insurance, despite being treated in clinical trials with standardized protocols, according to a study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

26 May 2022

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further investigation.

5 May 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

NQO2 gene as a novel potential target in Parkinson’s disease

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Study shows positive effect of concentrating surgery for children with neuroblastoma

Duke researchers find human DNA sequence divergence after split from common ancestor of chimpanzees

Lund researchers identify the reason behind chemoresistance in neuroblastoma

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Salk's three collaborative projects win 2022 Curebound Discovery Grant

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

New combination therapy shows potential to improve survival in children with neuroblastoma

New strategies to enhance the survival of children with neuroblastoma

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

CHOP helps launch new computational platform to harmonize pediatric cancer data

Novel targeted therapy may be an effective treatment option for neuroblastoma

Phase I clinical trial of new blocking antibody therapy shows promising results for the treatment of advanced medulloblastoma

New machine learning algorithm finds a gene signature characteristic of tumors

Study confirms the benefits of 'bridge therapy' for some children with high-risk neuroblastoma

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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