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Unraveling the biology of senescent cells and healthy aging

Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells.

29 Dec 2022

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

A research team at the Cluster of Excellence Physics of Life of TU Dresden and the University of California, Santa Barbara, reveals how cells sense their mechanical environment as they build tissues during embryogenesis.

28 Dec 2022

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

New mathematical model for the motion of bacteria

Biofilms form when microorganisms such as certain types of bacteria adhere to the surface of objects in a moist environment and begin to reproduce resulting in the excretion of a slimy glue-like substance.

28 Dec 2022

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

Virus-only diet can fuel the physiological and population growth of an organism

Over a single day, in the placid waters of a single pond, a million virus particles might enter a single-celled organism known for the minuscule hairs, or cilia, that propel it through those waters.

27 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

Type 2 diabetes mellitus is a common lifestyle disease that is prevalent worldwide. It can often lead to complications, such as diseases of the heart, and increased risk of death, but preventive measures, such as a healthy diet, can reduce these risks.

27 Dec 2022

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear's organ of Corti is vital for hearing.

27 Dec 2022

Breached dolphin's brains show neuropathology similar to Alzheimer's

In a new European Journal of Neuroscience study, scientists studied the brains of Odontocetes (Toothed whales) to document the presence or absence of neuropathological hallmarks of AD.

25 Dec 2022

Researchers design 3D structures made of DNA

Marvel at the tiny nanoscale structures emerging from research labs at Duke University and Arizona State University, and it's easy to imagine you're browsing a catalog of the world's smallest pottery.

23 Dec 2022

Study reveals why some germinal centers persist for months rather than weeks

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities.

23 Dec 2022

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

High levels of ammonia in tumors lead to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed.

23 Dec 2022

Researchers develop a lateral flow test to reliably identify and quantify allergens in foods

A team from the Universitat Politècnica de València, the Universitat de València, and the Centro de Investigación Biomédica en Red sobre Enfermedades Raras has developed a lateral flow test that identifies and quantifies the level of allergens reliably in food with the help of a smartphone.

23 Dec 2022

New technology achieves 99.7% purity in sorting target cells in real-time

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences have proposed a new technology, called optical tweezer-assisted pool-screening and single-cell isolation (OPSI) system, which achieves 99.7% purity of sorting target cells, with all done in real-time.

23 Dec 2022

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

High-calorie foods-;high in fat, oil, and sugar-;can taste good but often cause overeating, leading to obesity and major health problems. But what stimulates the brain to cause overeating?

23 Dec 2022

Researchers present a new strategy for self-adjuvanting vaccine development

This new article publication from Acta Pharmaceutica Sinica B, discusses a fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist KRN-7000 as built-in adjuvant effectively protects mice from tumor development.

23 Dec 2022

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

Life Science News

Unraveling the biology of senescent cells and healthy aging

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

New mathematical model for the motion of bacteria

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

Virus-only diet can fuel the physiological and population growth of an organism

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Xanthan gum-based fluid thickener can lower blood glucose levels after eating, study shows

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

Breached dolphin's brains show neuropathology similar to Alzheimer's

Researchers design 3D structures made of DNA

Study reveals why some germinal centers persist for months rather than weeks

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

Researchers develop a lateral flow test to reliably identify and quantify allergens in foods

New technology achieves 99.7% purity in sorting target cells in real-time

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

Researchers present a new strategy for self-adjuvanting vaccine development

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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