Hello folks, I have had a problem with my cholesterol, HDL ,LDL, and the whole works for about 15 years. I took all the drugs that I believed was destroying my liver and or kidneys, the dosage was increased on a regular basis and despite that I still wasn't keeping things under control. Sometime during or near 1999 a Doctor put me on 2000 mg of Niacin along with 4000 mg of fish oil. I'm happy to report everything is within limits. I don't know what gave me the best results, the Niacin or the fish oil but I do know that the combination did what the high priced drugs couldn't and believe me I took them all. Thank you for Niacin.