Thanks for your interest in the article on sublingual immunotherapy.
The preventative effect of sublingual immunotherapy (SLIT) on the onset of asthma in children with allergic rhinitis was shown in a study by Novembre et al- they followed 153 children with allergic rhinitis due grass pollen for 3 years. After 3 years, 45 children in the active group and 44 children in the control group were evaluated for the presence of asthma. 8/45 children in the SLIT group had developed asthma compared with 18/44 in the control group (P < 0.01). (Novembre E et al. JACI 2004; 114: 851-859).
Another study looking at the long-lasting benefit of SLIT was an open, controlled study involving more than 500 adult and adolescent patients. The onset of new sensitization after 3 years was 5.9% in the active group and 38% in the control group (P > 0.01). (Marogna M, Allergy 2004; 59: 1205-1210).
A third study by the same author (Marogna) showed that new sensitizations were found in 100% of the control subjects but in the different SLIT groups, new sensitization rates ranged from 11.7% - 21.4%. (Marogna, JACI 2010; 126 (5): 969- 975).
Cancel reply to comment
News-Medical.Net provides this medical information service in accordance
with these terms and conditions.
Please note that medical information found
on this website is designed to support, not to replace the relationship
between patient and physician/doctor and the medical advice they may provide.