80 percent of patients with schizophrenia experience at least one relapse within five years of diagnosis, and the risk for relapse in patients can substantially increase as a result of non-adherence. "Inconsistent compliance with medications is arguably one of the single greatest impediments to managing the symptoms of schizophrenia and delaying the time to relapse," said Henry A. Nasrallah, M.D., With this being said, how can a control group really be a controlled group. What happens to patients who take the drug outside of this controlled study. And it is expected of the physicians to ensure compliance outside of a controlled setting, Good luck with that one. Andrew Eriksen Cosmetic Director http://fractionalc02.com