Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Lilly granted MHRA marketing authorization in Great Britain for a ground-breaking UC therapy

Eli Lilly and Company announced today that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorisation (MA) for mirikizumab (OMVOH®) for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic treatment.

10 Jul 2023

Candidate genes for inflammatory bowel disease identified

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. The findings are published as a Reviewed Preprint in eLife.

5 Jul 2023

Research reveals how cells carry out the controlled release of mucins and insulin

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona have published a study in the journal Nature Communications that reveals how cells carry out the controlled release of mucins and insulin, two crucial proteins for human health.

3 Jul 2023

New drug effective as a treatment against ulcerative colitis, clinical trial shows

A new drug, investigated by Amsterdam UMC together with colleagues around the world, is effective as a treatment against ulcerative colitis.

28 Jun 2023

Study reveals a co-pathogenesis mechanism of acute myocardial infarction and ulcerative colitis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiovascular diseases, particularly acute myocardial infarction, are the leading cause of disability and death.

15 Jun 2023

IBD patients more likely to have a stroke than people without the disease

People with inflammatory bowel disease (IBD) are more likely to have a stroke than people without the disease, according to a study published in the June 14, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology. The study does not prove that IBD causes stroke; it only shows an association.

14 Jun 2023

So-called “orphan” drugs earn pharmaceutical companies as much money as mainstream medicines

Drugs used to treat rare conditions are earning pharmaceutical companies almost as much as those marketed to the general public, according to a researcher at West Virginia University. Sean Tu, a College of Law professor found lucrative so-called "orphan" drugs earn manufacturing tax credits, have longer patent exclusivities and face easier Food and Drug Administration review.

12 Jun 2023

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.

31 May 2023

Long-term consequences of COVID-19 in patients with inflammatory rheumatic diseases

Studies on the long-term consequences of COVID-19 (long-COVID) in patients with inflammatory rheumatic diseases (iRD) are scarce.

31 May 2023

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Research paper discusses the relationship between iron deficiencies and immune tolerance in patients with inflammatory bowel disease. The study shows that high cellular iron levels fostered by pentanoate, a short-chain fatty acid produced by intestinal microbiota, are necessary for the homeostasis of regulatory T cells in the intestine, and iron deficiencies in Treg can result in lethal autoimmune disease.

17 May 2023

Using synthetic peptides for inflammatory disease diagnosis

Scientists have developed a peptide that binds to the protein calprotectin, a marker of major inflammatory disorders, and shown that it is suitable for diagnostic tests.

17 May 2023

Researchers map the immune system in the gut of kids with inflammatory bowel disease

Researchers from Karolinska Institutet and Sachs' Children and Youth Hospital in Sweden have mapped the immune system in the gut of children with inflammatory bowel disease (IBD).

9 May 2023

Study suggests significantly earlier diagnosis may be possible for some chronic conditions

Conditions such as celiac disease and Parkinson's disease could be detected in principle up to 10 years earlier than they are currently, suggests a new study by UCL researchers.

5 May 2023

Crohn’s disease: Symptoms, diagnosis, and treatments

Anyone newly diagnosed with Crohn's disease likely has a lot of questions – and probably some anxiety – about having a chronic ailment for which there's no cure.

4 May 2023

The potential anti-cancer and antioxidant properties of walnuts

Researchers reviewed current literature to examine walnuts' potential antioxidant and anti-cancer properties.

25 Apr 2023

Lymphoma risk is slightly elevated in patients with IBD

The risk of developing lymphoma is slightly elevated in inflammatory bowel disease (IBD) and has increased in recent years in patients with Crohn's disease, report researchers from Karolinska Institutet in a study published in Clinical Gastroenterology and Hepatology.

21 Apr 2023

Early-life gut microbial dysbiosis exacerbates colitis

A recent Research journal study investigated the role of microbiota linked to the anaerobic plasmalogen biosynthetic pathway in establishing intestinal homeostasis. The study hypothesized that the presence of pls [PlsA/R]-positive bacterial species and plasmalogen bestow valuable intestine homeostasis in early life.

13 Apr 2023

Study illuminates how patients with variants in the PTPN2 gene develop IBD

Inflammatory bowel disease, or IBD, describes Crohn's disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune disorder -; a condition in which the body's immune system attacks healthy tissues.

7 Apr 2023

Does higher caffeine and coffee intake impact colonic microbiota composition and diversity?

Researchers investigated the association between caffeine and the colonic microbiome.

6 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Lilly granted MHRA marketing authorization in Great Britain for a ground-breaking UC therapy

Candidate genes for inflammatory bowel disease identified

Research reveals how cells carry out the controlled release of mucins and insulin

New drug effective as a treatment against ulcerative colitis, clinical trial shows

Study reveals a co-pathogenesis mechanism of acute myocardial infarction and ulcerative colitis

IBD patients more likely to have a stroke than people without the disease

So-called “orphan” drugs earn pharmaceutical companies as much money as mainstream medicines

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Long-term consequences of COVID-19 in patients with inflammatory rheumatic diseases

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Using synthetic peptides for inflammatory disease diagnosis

Researchers map the immune system in the gut of kids with inflammatory bowel disease

Study suggests significantly earlier diagnosis may be possible for some chronic conditions

Crohn’s disease: Symptoms, diagnosis, and treatments

The potential anti-cancer and antioxidant properties of walnuts

Lymphoma risk is slightly elevated in patients with IBD

Early-life gut microbial dysbiosis exacerbates colitis

Study illuminates how patients with variants in the PTPN2 gene develop IBD

Does higher caffeine and coffee intake impact colonic microbiota composition and diversity?

Interplay between Western diet, gut microbiota, and cancer development

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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