Cystic Fibrosis

Cystic fibrosis is a life threatening, inherited disease of the exocrine glands. The condition primarily affects the digestive and respiratory systems which become clogged with a thick, sticky mucus. Cystic fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene which results in an excess of salt and water passing into cells, causing a thick, sticky mucus to build up in bodily passageways.

Cystic Fibrosis (CF)

Cystic fibrosis is a genetic condition that affects the production and flow of mucus within the lungs and digestive system, parts of the body that then become clogged with a thick, sticky mucus.

Cystic Fibrosis Causes

Cystic Fibrosis Symptoms

Cystic Fibrosis Diagnosis

Cystic Fibrosis Treatment

Genetics of Cystic Fibrosis

Cystic Fibrosis Screening

Cystic Fibrosis Questions

Coping With Cystic Fibrosis

Cystic Fibrosis Facts

Cystic Fibrosis Epidemiology

Cystic Fibrosis Prognosis

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Cystic Fibrosis Research

Could CRISPR Repair CFTR in Cystic Fibrosis Patients?

Sweat Test for Cystic Fibrosis

Cystic Fibrosis and Salty Skin

Cystic Fibrosis Evolution

Lung Transplantation for Cystic Fibrosis

Gene Therapy as a Potential Cure for Cystic Fibrosis

Cystic Fibrosis and Infertility

Cystic Fibrosis History

Tests for Cystic Fibrosis During Pregnancy

Latest Cystic Fibrosis News and Research

Enterprise Therapeutics appoints Dr Renu Gupta as Chief Medical Officer and Dr Janet Hammond as Non-Executive Director

Appointments bring additional respiratory and late clinical-stage drug development experience as Company commences Phase 2a clinical trial of its lead asset.

From Enterprise Therapeutics Ltd 17 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

Biden’s on target about what repealing ACA would mean for preexisting condition protections

President Joe Biden's reelection campaign wants voters to contrast his record on health care policy with his predecessor's.

13 Jun 2024

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in the Journal of Cystic Fibrosis1.

12 Jun 2024

Study uncovers two types of dysbiosis in cystic fibrosis

Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis.

11 Jun 2024

Efficient whole-gene insertions can be achieved with improved gene-editing technology

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications.

10 Jun 2024

Multiple general anesthesia exposure does not compromise brain function in young children, study finds

A University of Queensland-led study has found multiple doses of anesthetics do not compromise brain function in young children.

10 Jun 2024

Innovative sweat monitoring device enables non-invasive health monitoring

Sweat contains biomarkers that can monitor various health conditions, from diabetes to genetic disorders. Sweat sampling, unlike blood collection, is preferred by users due to its painless nature.

28 May 2024

Scientists uncover protein folding secrets through sound

By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein.

21 May 2024

Understanding public perception of polygenic embryo screening for IVF

Three out of four U.S. adults support the use of emerging technologies that estimate a future child's likelihood of developing health conditions influenced by multiple genes -; such as diabetes, heart disease, and depression -; before an embryo is implanted during in vitro fertilization (IVF), according to a new public opinion survey led by researchers at Harvard Medical School.

15 May 2024

Study sheds light on challenges faced by caregivers of children with genetic conditions

When it comes to improving the lives of children with genetic conditions, medical research often focuses solely on the children. But there is an equally important population in need of research that a faculty member at the University of Colorado Department of Medicine is highlighting -; the caregivers.

10 May 2024

Innovative methodologies for investigating intestinal mucus properties and response

As much as we might not want to think about it, mucus is everywhere in our bodies. It coats our airways and our digestive systems and serves as a first line of defense against pathogens, a habitat for our microbiomes, and a conveyor belt for our insides to keep everything moving smoothly.

7 May 2024

Purdue researcher receives $2.4 million NIH grant to combat antimicrobial resistance in lung infections

Qi "Tony" Zhou, a researcher in Purdue University's College of Pharmacy has received a $2.4 million grant from the National Institutes of Health to fight lung infections that have established a resistance to antimicrobial drugs.

6 May 2024

Electric pulses boost gene therapy uptake in liver cells

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies.

30 Apr 2024

RNA editing using CRISPRs shows promise for genetic disease treatment

A team at Montana State University published research this week that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs.

29 Apr 2024

Hospital toilets harbor multi-drug resistant "superbugs", study finds

Pathogenic bacteria and fungi, including multi-drug resistant "superbugs" have been found on the floors, ceilings, door handles and other surfaces of hospital toilets in the UK, with patient toilets the worst affected, the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) will hear.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Human mini-lungs mimic animal response to nanomaterials

Human mini-lungs grown by University of Manchester scientists can mimic the response of animals when exposed to certain nanomaterials.

27 Apr 2024

Study highlights how age affects nasal cell response to SARS-CoV-2

Researchers reveal age-related differences in nasal epithelial cell responses to SARS-CoV-2, showing variations in cell types and viral dynamics across pediatric, adult, and older adult groups.

16 Apr 2024

Cystic fibrosis drug found to be safe and effective in newborns

A Cystic Fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective in newborns aged four weeks and above, new research involving RCSI University of Medicine and Health Sciences and Children's Health Ireland has found.

12 Apr 2024