Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

New research from cancer research and treatment organization City of Hope in the December 2022 issue of JNCCN-;Journal of the National Comprehensive Cancer Network finds that only 30% of patients with advanced neuroendocrine tumors (NETs) say their top goal for treatment is living longer.

12 Dec 2022

Novel drug shows early potential in combating multiple myeloma

A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer Center at the 2022 American Society of Hematology Annual Meeting (Abstract 565).

12 Dec 2022

Simplified treatment regimen results in dramatic decrease in early deaths from acute promyelocytic leukemia

The use of a simplified treatment regimen by oncologists, along with management recommendations and 24/7 support provided by a limited and dedicated group of academic disease experts, resulted in a dramatic decrease in early deaths from acute promyelocytic leukemia (APL).

12 Dec 2022

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

A three-drug combination that sent chronic lymphocytic leukemia (CLL) into deep remissions in a broad group of patients in a clinical trial is highly effective in patients with high-risk forms of the disease, a new, phase 2 clinical trial led by Dana-Farber Cancer Institute investigators indicates.

12 Dec 2022

Extra year of chemotherapy lowers the risk of cancer recurrence in children with Ikaros leukemia

Many children with ALL have a good outcome of their disease. After two years of chemotherapy treatment, nine out of ten children are cured. But some children have a more aggressive form of the disease.

12 Dec 2022

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Researchers from the University of Pennsylvania's Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose cancers relapsed after previous CAR T therapy at the 2022 American Society of Hematology Annual Meeting.

12 Dec 2022

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

12 Dec 2022

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

The COVID-19 global pandemic remains a major public health challenge. ASCOT researchers aim to discover which treatments are most effective in patients hospitalized with COVID-19.

12 Dec 2022

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

For patients with sickle cell disease, fertility care is about reproductive justice

Teonna Woolford has always wanted six kids. Why six? "I don't know where that number came from. I just felt like four wasn't enough," said Woolford, a Baltimore resident. "Six is a good number."

8 Dec 2022

Cancer immunotherapies can become more potent depending on the time of day

Scientists from the UNIGE and LMU show that the anti-tumor activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day.

7 Dec 2022

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

The critical role of flow cytometry in CAR+ T-Cell trials

In this interview, Ryan Muise talks to AZoNetwork about the added value of using flow cytometry in CAR T-Cell clinical trials.

From Cerba Research 6 Dec 2022

AI could make doctors’ work simpler, faster, and more precise

One in nine women in the developed world will be diagnosed with breast cancer at some point in her life. The prevalence of breast cancer is increasing, an effect caused in part by the modern lifestyle and increased lifespans.

2 Dec 2022

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Studying mice has filled encyclopedias with breakthrough medical discoveries. But when it comes to brain cancers, the little rodents have long exhibited fundamental limitations.

30 Nov 2022

UC San Diego receives $8 million CIRM funding to expedite stem cell therapy clinical trials

Stem cells show particular promise in treating diseases for which few other effective treatments exist. In these therapies, stem cells are introduced into the body where they develop into specialized cells that repair, restore, replace or regenerate cells that have been damaged by the disease.

21 Nov 2022

Caregivers’ coping strategies affect their level of distress and quality of life

November is Caregiver Awareness Month, and timely findings from a study published in Blood Advances suggest that, among caregivers of patients undergoing a stem cell transplant, how someone approaches coping can influence their levels of anxiety, depression, and poor quality of life (QOL) they experience.

20 Nov 2022

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

A new molecular imaging radiotracer can precisely diagnose a variety of cancers, providing a roadmap to identify patients who may benefit from targeted radionuclide therapies.

20 Nov 2022

New, automated system calculates metabolic tumor volume in diffuse large B-cell lymphoma

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a new, automated way to calculate metabolic tumor volume (MTV) in diffuse large B-cell lymphoma (DLBCL).

15 Nov 2022

Hematology News and Research

Further Reading

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

Novel drug shows early potential in combating multiple myeloma

Simplified treatment regimen results in dramatic decrease in early deaths from acute promyelocytic leukemia

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

Extra year of chemotherapy lowers the risk of cancer recurrence in children with Ikaros leukemia

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

For patients with sickle cell disease, fertility care is about reproductive justice

Cancer immunotherapies can become more potent depending on the time of day

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

The critical role of flow cytometry in CAR+ T-Cell trials

AI could make doctors’ work simpler, faster, and more precise

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

UC San Diego receives $8 million CIRM funding to expedite stem cell therapy clinical trials

Caregivers’ coping strategies affect their level of distress and quality of life

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

New, automated system calculates metabolic tumor volume in diffuse large B-cell lymphoma

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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