Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Weight-based dosing strategy may affect immunotherapy outcomes, shows study

Overweight cancer patients receiving immunotherapy treatments live more than twice as long as lighter patients, but only when dosing is weight-based, according to a study by cancer researchers at UT Southwestern Medical Center.

15 Jun 2021

Analysis of COVID-19 patients with repeatedly positive SARS-CoV-2 tests

New research published on the medRxiv preprint server provides a detailed analysis of COVID-19 patients who had repeated positive PCR tests for SARS-CoV-2 infection in a large US COVID-19 electronic health record (EHR) database.

15 Jun 2021

Study reveals risk factors associated with COVID-19 outcomes for people with IDD

A study of nearly 550 adults with intellectual and developmental disabilities receiving residential services in New York City found that age, larger residential settings, Down syndrome and chronic kidney disease were the most common risk factors for COVID-19 diagnosis, and heart disease was most associated with COVID-19 deaths.

14 Jun 2021

High proportion of people with diabetes have chronic kidney disease, research reveals

Some 42% of patients attending a dedicated diabetes clinic have signs of established chronic kidney disease, the first detailed research of its kind in Ireland has revealed.

14 Jun 2021

Plant-based diet appears to offer protection against hypertension and preeclampsia

A plant-based diet appears to afford significant protection to rats bred to become hypertensive on a high-salt diet, scientists report. When the rats become pregnant, the whole grain diet also protects the mothers and their offspring from deadly preeclampsia.

14 Jun 2021

New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Research suggests low platelet counts may be associated with Oxford-AstraZeneca vaccine

A condition that affects the blood, known as idiopathic thrombocytopenic purpura (ITP), may be associated the Oxford-AstraZeneca vaccine in rare cases, research suggests.

9 Jun 2021

NIH-funded study to explore liquid surface coatings for reducing catheter-associated infections

A novel liquid surface coating on human catheters could help reduce protein deposition that leads to urinary tract and bloodstream infections, according to researchers at the University of Maine and University of Notre Dame who are leading a study funded by the National Institutes of Health.

9 Jun 2021

Researchers map potential toxicity of lanthanide metals used in medicine

Lanthanides are rare-earth heavy metals with useful magnetic properties and a knack for emitting light. Researchers had long assumed that lanthanides' toxicity risk was low and therefore safe to implement in a number of high-tech breakthroughs we now take for granted: from OLEDs (organic light-emitting displays)¬¬ to medical MRIs and even hybrid vehicles.

9 Jun 2021

AI-powered tool could accelerate the diagnosis of cardiovascular diseases

A team of researchers from Nanyang Technological University, Singapore, Ngee Ann Polytechnic, Singapore, and the National Heart Centre Singapore have invented a tool that could speed up the diagnosis of cardiovascular diseases.

8 Jun 2021

Treating critically ill COVID-19 patients with non-altered umbilical cord stem cells increases survival

Critically ill COVID-19 patients treated with non-altered stem cells from umbilical cord connective tissue were more than twice as likely to survive as those who did not have the treatment, according to a study published today in STEM CELLS Translational Medicine.

8 Jun 2021

Kidney experts say it’s time to remove race from medical algorithms. Doing so is complicated.

Alphonso Harried recently came across a newspaper clipping about his grandfather receiving his 1,000th dialysis treatment. His grandfather later died — at a dialysis center — as did his uncle, both from kidney disease.

8 Jun 2021

Skin disorders on the rise during COVID‐19 pandemic due to infection and PPE use

An increase in personal protective equipment (PPE) use and hygiene measures such as the use of hand sanitizers, hand washing, and mask usage during this pandemic have increased the frequency of dermatological diseases.

8 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

New study could help guide oncologists in selecting the best treatment for kidney cancers

Not all kidney cancers behave the same, with wildly different responses to immunotherapy or other treatments – and wildly different outcomes for patients as a result.

8 Jun 2021

Wearable sensor shows link between blood pressure and intracranial pressure

Brazilian researchers have simultaneously demonstrated the mechanism linking high blood pressure to elevated intracranial pressure, validated a non-invasive intracranial pressure monitoring method, and proposed a treatment for high blood pressure that does not affect intracranial hypertension.

8 Jun 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

Link between SARS-CoV-2 organotropism and kidney injury

It was clear at a relatively early stage of the pandemic that SARS-CoV-2 causes a wide range of symptoms; in addition to typical respiratory symptoms, patients also had neurological symptoms (starting with anosmia), gastrointestinal symptoms, elevated liver values, and renal, urinary or hematological changes, for example.

8 Jun 2021

Addressing climate change for better kidney health

Health has always been affected by climate and weather, but is increasingly clear that the change in climate is a significant threat to human health.

7 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

Nephrology News and Research

Further Reading

Weight-based dosing strategy may affect immunotherapy outcomes, shows study

Analysis of COVID-19 patients with repeatedly positive SARS-CoV-2 tests

Study reveals risk factors associated with COVID-19 outcomes for people with IDD

High proportion of people with diabetes have chronic kidney disease, research reveals

Plant-based diet appears to offer protection against hypertension and preeclampsia

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Research suggests low platelet counts may be associated with Oxford-AstraZeneca vaccine

NIH-funded study to explore liquid surface coatings for reducing catheter-associated infections

Researchers map potential toxicity of lanthanide metals used in medicine

AI-powered tool could accelerate the diagnosis of cardiovascular diseases

Treating critically ill COVID-19 patients with non-altered umbilical cord stem cells increases survival

Kidney experts say it’s time to remove race from medical algorithms. Doing so is complicated.

Skin disorders on the rise during COVID‐19 pandemic due to infection and PPE use

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

New study could help guide oncologists in selecting the best treatment for kidney cancers

Wearable sensor shows link between blood pressure and intracranial pressure

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

Link between SARS-CoV-2 organotropism and kidney injury

Addressing climate change for better kidney health

Study reports safety, efficacy of targeted treatment for IgA nephropathy

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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