Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

New EULAR recommendations provide updated treatment strategies for systemic sclerosis

SSc is a rare connective tissue disorder, with both autoimmune and vascular features. The main hallmark is tissue and vascular fibrosis that can result in clinical heterogeneity of manifestations across the skin and internal organs.

14 Oct 2024

Calluna Pharma appoints Mark Gaffney as Chief Executive Officer and Mark Altmeyer as Independent Chair of the Board

Calluna Pharma AS (Calluna), a clinical stage biotechnology company pioneering first-in-class antibodies to treat inflammatory and fibrotic diseases, today announced the appointments of Mark Gaffney as Chief Executive Officer and Mark Altmeyer as Chair of the Board.

From Calluna Pharma 14 Oct 2024

Researchers awarded $7 million to innovate probiotic treatments for lung infections

University of California San Diego and University of California Berkeley researchers have been awarded up to $7 million from the Advanced Research Projects Agency for Health (ARPA-H) to conduct research under the PROTECT project -; Pro/Prebiotic Regulation for Optimized Treatment and Eradication of Clinical Threats.

10 Oct 2024

New surgical stitches capable of generating electrical charge may accelerate wound healing

Researchers developed the BioES-suture, a bioabsorbable suture that accelerates wound healing through electrical stimulation, showing superior healing outcomes.

10 Oct 2024

New research offers hope for treating metabolic dysfunction-associated liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) — previously known as "non-alcoholic fatty liver disease" — affects about 25% of the global population.

9 Oct 2024

Vitamin B12 boosts testosterone levels in men with infertility

Research finds that higher serum vitamin B12 levels are associated with improved testosterone concentrations in men with infertility, but no impact on other reproductive hormones.

30 Sep 2024

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Research indicates that high flavonoid intake is linked to a lower risk of NAFLD, with apples and tea showing significant protective effects on liver health.

30 Sep 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

Epigenetic switch controls renin production in unexpected cell type

University of Virginia School of Medicine researchers have discovered how certain cells have the amazing ability to transform their function to help our bodies control our blood pressure.

26 Sep 2024

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Crohn's disease -; an autoimmune disorder -; is characterized by chronic inflammation of the digestive tract, resulting in a slew of debilitating gastrointestinal symptoms that vary from patient to patient.

26 Sep 2024

Antiviral drug molnupiravir linked to new mutations in SARS-CoV-2

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown.

26 Sep 2024

Targeted drug therapy shows promise for ulcerative colitis remission

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission.

26 Sep 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

Study sheds light on mechanisms behind liver fibrosis and potential therapies

New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.

25 Sep 2024

Research reveals key role of mucin modification in muco-obstructive diseases

With each breath, a human may inhale thousands of harmful microbes into the lungs. Mucus, the gel-like moist substance coating the airways, is one of the first lines of defense and aids in removal these microbes.

24 Sep 2024

Anti-fibrotic drug shows promise in breast cancer

The most common breast cancer is HER2-negative, so called because it has low amounts of one of the proteins that contribute to tumor cell growth, HER2. Despite this common trait, the development of HER2-negative cancers varies among patients, so one goal is to be able to classify tumors in more detail and thus determine the best treatment for each case.

20 Sep 2024

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.

19 Sep 2024

Early intervention key for mental health in children with cystic fibrosis

A University at Buffalo psychiatrist who has played a critical role in getting mental health screening and treatment integrated into routine care for adults and adolescents with cystic fibrosis (CF) has been awarded $3 million from the Cystic Fibrosis Foundation to focus on the mental health of children with the disease.

19 Sep 2024

Lupus Research Alliance announces 2024 Diversity in Lupus Research Award recipients

The Lupus Research Alliance (LRA) is pleased to announce the recipients of the 2024 Career Development and Postdoctoral Awards to Promote Diversity in Lupus Research.

17 Sep 2024

Fibrosis News and Research

Further Reading

New EULAR recommendations provide updated treatment strategies for systemic sclerosis

Calluna Pharma appoints Mark Gaffney as Chief Executive Officer and Mark Altmeyer as Independent Chair of the Board

Researchers awarded $7 million to innovate probiotic treatments for lung infections

New surgical stitches capable of generating electrical charge may accelerate wound healing

New research offers hope for treating metabolic dysfunction-associated liver disease

Vitamin B12 boosts testosterone levels in men with infertility

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Epigenetic switch controls renin production in unexpected cell type

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Antiviral drug molnupiravir linked to new mutations in SARS-CoV-2

Targeted drug therapy shows promise for ulcerative colitis remission

New pipeline of drug candidates offers hope for effective MASLD treatments

Study sheds light on mechanisms behind liver fibrosis and potential therapies

Research reveals key role of mucin modification in muco-obstructive diseases

Anti-fibrotic drug shows promise in breast cancer

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Early intervention key for mental health in children with cystic fibrosis

Lupus Research Alliance announces 2024 Diversity in Lupus Research Award recipients

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