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TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem.

21 Nov 2016

Study shows how Zika virus infection leads to production of smaller disease-causing RNAs

Researchers, led by scientists at the University of Colorado School of Medicine, have found basic molecular processes used by the Zika virus to "hijack" the cells that it infects and potentially how it makes molecules that are directly linked to disease.

11 Nov 2016

Researchers lay foundation for improved TB treatment by targeting new enzyme

Researchers at Johns Hopkins report they have laid the foundation to develop novel antibiotics that work against incurable, antibiotic-resistant bacteria like tuberculosis by targeting an enzyme essential to the production and integrity of bacterial cell walls.

10 Nov 2016

Scientists unravel viral molecular strategies to counter mammalian immune system

As mammals evolve, so do mammalian viruses. In doing so, they develop creative and effective ways to counter and evade the antiviral responses of their mammal hosts' immune systems.

7 Nov 2016

Researchers create detailed blueprint of how the body transports zinc to maintain good health

Zinc is essential for wound healing, for vision, for DNA creation, for our senses of taste and smell, even for sexual health. But despite its importance, scientists have never fully understood the mechanism that moves the mineral through the body - until now.

7 Nov 2016

Researchers create detailed blueprints of molecular moving vans that transport zinc everywhere

4 Nov 2016

UT Southwestern researcher wins prestigious 2016 Transformative Research Award

Dr. Rama Ranganathan, Director of the Cecil H. and Ida Green Comprehensive Center for Molecular, Computational, and Systems Biology at UT Southwestern Medical Center, has been awarded a prestigious 2016 Transformative Research Award from the National Institutes of Health's Common Fund.

17 Oct 2016

Virginia Tech scientists solve structure of enzyme that deactivates important antibiotic

A popular antibiotic called rifampicin, used to treat tuberculosis, leprosy, and Legionnaire's disease, is becoming less effective as the bacteria that cause the diseases develop more resistance.

7 Oct 2016

Scientists uncover how microbes invade the brain in bacterial meningitis

Simon Fraser University researcher Lisa Craig is part of an international team that has uncovered new details about a microbe that invades the brain, sometimes with fatal results.

6 Oct 2016

X-ray laser-based technology enables faster structural analysis of receptor proteins

An international team of scientists has learnt how to determine the spatial structure of a protein obtained with an X-ray laser using the sulfur atoms it contains. This development is the next stage in the project of a group led by Vadim Cherezov to create an effective method of studying receptor proteins.

30 Sep 2016

Scientists solve structure of BinAB toxin that kills larvae of certain type of mosquitoes

Could we get rid of mosquitoes without polluting the environment? Yes, we can! The BinAB toxin, produced in crystal form by a bacterium, specifically kills the larvae of Culex and Anopheles mosquitoes, but it is inactive on tiger mosquitoes (or Aedes), the vectors for dengue fever and chikungunya.

29 Sep 2016

Research uncovers new clues to combat dengue and Zika virus

Structural biology research conducted at the U.S. Department of Energy's SLAC National Accelerator Laboratory has uncovered how small insecticidal protein crystals that are naturally produced by bacteria might be tailored to combat dengue fever and the Zika virus.

28 Sep 2016

Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

My research lab studies several classes of systems. We are mostly interested in looking at large protein assemblies to understand their structure, dynamics and how their properties relate to their malfunction in disease.

From Bruker BioSpin - NMR, EPR and Imaging 21 Sep 2016

AXT to exclusively distribute Unchained Labs biologics research tools in Australia, New Zealand

AXT is excited to announce that they have partnered with Unchained Labs and will now be exclusively distributing their innovative and novel range of instruments for the analysis and formulation of biologics in Australia and New Zealand.

From AXT Pty Ltd 20 Sep 2016

Scientists begin research work at new £650 million Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs.

20 Sep 2016

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications.

8 Sep 2016

Research findings of protein may form foundation for new approach to antibiotics

Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.

1 Sep 2016

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy.

31 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

EPFL scientists discover new path to combat pathogenic bacteria

Bacteria that cause tuberculosis, leprosy and other diseases, survive by switching between two different types of metabolism.

24 Aug 2016