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Treatment with AMG 145 reduces LDL cholesterol

Amgen today announced that results from the LAPLACE-TIMI 57 and MENDEL Phase 2 studies evaluating AMG 145 in hypercholesterolemic patients with or without statins, respectively, showed that treatment with AMG 145 resulted in a statistically significant reduction in low-density lipoprotein (LDL) cholesterol.

7 Nov 2012

People more likely to die of heart-related issues in winter

No matter what climate you live in, you're more likely to die of heart-related issues in the winter, according to research presented at the American Heart Association's Scientific Sessions 2012.

7 Nov 2012

Link between SFRP4 protein and risk of type 2 diabetes

When a patient is diagnosed with type 2 diabetes, the disease has usually already progressed over several years and damage to areas such as blood vessels and eyes has already taken place. To find a test that indicates who is at risk at an early stage would be valuable, as it would enable preventive treatment to be put in place.

7 Nov 2012

Weight loss can help improve quality of sleep among obese people

Weight loss, whether it's from dietary changes alone or from diet combined with exercise, can help improve the quality of sleep among people who are overweight or obese, according to a new study by Johns Hopkins researchers.

7 Nov 2012

Results from liraglutide and exenatide head-to-head comparison trial on type 2 diabetes

A direct, head-to-head comparison of two of the newer treatments available for type 2 diabetes yielded mixed results.

7 Nov 2012

Researchers develop new kind of intracranial pressure sensor

An increase in cerebral pressure may cause dementia and could destroy the brain. Companies have been seeking to find monitoring sensors that can be implanted into the brain, and read from outside the body. A tiny sensor may provide the help needed.

7 Nov 2012

Lexicon announces data from LX4211 Phase 2b trial on type 2 diabetes

Lexicon Pharmaceuticals, Inc. announced that data from the Phase 2b clinical trial of LX4211 are being presented today as a Clinical Sciences Special Report in the Emerging Therapeutics for Diabetes and Dyslipidemia section of the American Heart Association (AHA) Scientific Sessions Conference held in Los Angeles, California.

7 Nov 2012

Young adults with high blood pressure less likely to be diagnosed during doctor visits

Adults 18-24 years old with high blood pressure were 28 percent less likely to be diagnosed during doctor visits than those 60 and older, according to findings presented at the American Heart Association's Scientific Sessions 2012.

7 Nov 2012

MASP-1 enzyme plays a central role in activating the complement system

Researchers from Aarhus University, Denmark, have now discovered an important mechanism behind one of our most fundamental lines of immune function. The discovery has been published in the esteemed scientific journal, The Journal of Immunology, where it has been highlighted as a top story.

7 Nov 2012

Measuring blood levels of hs-CRP could help identify men at increased risk for death from cancer

Measuring blood levels of high-sensitive C-reactive protein, an important marker of inflammation, in apparently cancer-free men could potentially help identify those at increased risk for death from cancer, in particular lung cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

7 Nov 2012

EPO provides notice of intent to issue European Patent Application for Aethlon Hemopurifier

Aethlon Medical, Inc., the pioneer in developing selective therapeutic filtration devices to address infectious disease, cancer and other life-threatening conditions, announced today that the European Patent Office (EPO) has provided the Company a notice of intent to issue European Patent Application No. 04 703 672.8 entitled "Method For Removal of Viruses From Blood By Lectin Affinity Hemodialysis."

7 Nov 2012

Loyola announces 2012 Junior and Senior Scientist of the Year during St. Albert's Day

Katherine L. Knight, PhD, one of the nation's leading immune system researchers, has been named 2012 Senior Scientist of the Year at Loyola University Chicago Stritch School of Medicine. Sakthivel Sadayappan, PhD, FAHA, who is doing groundbreaking research on a protein that is critical for the normal functioning of the heart, has been named 2012 Junior Scientist of the Year.

7 Nov 2012

Cause of heart attacks or strokes may be different in some patients treated with anti-platelet drugs

The cause of heart attacks or strokes among some patients treated with anti-platelet drugs may be different than for patients who have undergone surgical procedures to restore blood flow, according to researchers at Duke Medicine.

7 Nov 2012

Scientists identify group of small molecules that interfere with polyphosphate activity

Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition called thrombosis. Blocking the activity of this compound, polyphosphate, could treat thrombosis with fewer bleeding side effects than the drugs that are currently on the market.

7 Nov 2012

UCLA study to uncover risk profiles of breast cancer survivors likely to suffer from depression

UCLA researchers received a five-year, $5 million grant from the National Cancer Institute that will fund a study seeking to uncover risk profiles of breast cancer survivors likely to suffer from depression.

7 Nov 2012

Turning off GSK-3α protein activity can prevent heart remodeling

When a person has a heart attack, portions of the heart muscle die in the next several days or even weeks if deprived of oxygen for long enough. The recovering heart slowly remodels itself, even fostering the growth of new blood vessels, in an attempt to regain some of its former function. But all too often, the remodeling is actually harmful, and the damaged heart is on an inevitable downward slide to heart failure.

6 Nov 2012

Researchers show how bacteria control processes in human cells

Bacteria can talk to each other via molecules they themselves produce. The phenomenon is called quorum sensing, and is important when an infection propagates. Now, researchers at Link-ping University in Sweden are showing how bacteria control processes in human cells the same way.

6 Nov 2012

Geldanamycin degrades VEGFR2 protein that triggers blood vessel growth

The drug, geldanamycin, is well known for attacking a protein associated with the spread of breast cancer. However, a laboratory-based study found it also degraded a different protein that triggers blood vessel growth.

6 Nov 2012

Pfizer receives FDA approval for Xeljanz to treat rheumatoid arthritis

The U.S. Food and Drug Administration today approved Xeljanz (tofacitinib) to treat adults with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to, or who are intolerant of, methotrexate.

6 Nov 2012

Brain bleeds in premature babies: an interview with Edward Ahn

Premature babies are born during their third trimester and they are vulnerable to having brain bleeds because their brains are not completely developed. There are some fragile blood vessels that are present in every developing infant, but when the babies are born early, these blood vessels can be subject to changes in blood pressure and changes in breathing patterns and, due to their fragility, they can develop a hemorrhage.

6 Nov 2012

Blood News and Research

Treatment with AMG 145 reduces LDL cholesterol

People more likely to die of heart-related issues in winter

Link between SFRP4 protein and risk of type 2 diabetes

Weight loss can help improve quality of sleep among obese people

Results from liraglutide and exenatide head-to-head comparison trial on type 2 diabetes

Researchers develop new kind of intracranial pressure sensor

Lexicon announces data from LX4211 Phase 2b trial on type 2 diabetes

Young adults with high blood pressure less likely to be diagnosed during doctor visits

MASP-1 enzyme plays a central role in activating the complement system

Measuring blood levels of hs-CRP could help identify men at increased risk for death from cancer

EPO provides notice of intent to issue European Patent Application for Aethlon Hemopurifier

Loyola announces 2012 Junior and Senior Scientist of the Year during St. Albert's Day

Cause of heart attacks or strokes may be different in some patients treated with anti-platelet drugs

Scientists identify group of small molecules that interfere with polyphosphate activity

UCLA study to uncover risk profiles of breast cancer survivors likely to suffer from depression

Turning off GSK-3α protein activity can prevent heart remodeling

Researchers show how bacteria control processes in human cells

Geldanamycin degrades VEGFR2 protein that triggers blood vessel growth

Pfizer receives FDA approval for Xeljanz to treat rheumatoid arthritis

Brain bleeds in premature babies: an interview with Edward Ahn

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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