Respiratory News and Research

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Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

A new study published in mBio discusses the microevolution of SARS-CoV-2.

31 Aug 2021

Does SARS-CoV-2 infection protect against reinfection?

A new review showed that the protective effect of prior SARS-CoV-2 infection is at least equivalent to that of vaccination.

31 Aug 2021

Researchers identify biomarkers for rare, serious complication in children with COVID-19

The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19.

31 Aug 2021

Anti-SARS-CoV-2 immunity induced by Pfizer/BioNTech vaccine may decline after 6 months

A team of scientists from Israel has recently claimed that antiviral immunity induced by the mRNA-based coronavirus disease 2019 (COVID-19) BNT162b2 gradually declines over time, highlighting the need for a third booster dose.

31 Aug 2021

mRNA COVID-19 vaccines induce high antibody titers with significant neutralizing potency in saliva

Scientists from the USA and Canada have recently demonstrated that the dynamics of antibody response induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (COVID-19) vaccines are different.

31 Aug 2021

Post-infection vaccination produces potent neutralizing antibodies against SARS-CoV-2 variants

The best protection against new SARS-CoV-2 infections or reinfections may be obtained by a combination of vaccine-elicited and infection-induced antibodies.

31 Aug 2021

J&J COVID-19 booster shot produces robust antibody response

The study showed neutralizing antibody responses produced by the Johnson & Johnson–Janssen vaccine was robust and stable eight months after immunization.

31 Aug 2021

Researchers develop adult lung organoids that represent all cell types

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived.

31 Aug 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Smart shirt made with carbon nanotube thread monitors the wearer’s heart rate

There's no need to don uncomfortable smartwatches or chest straps to monitor your heart if your comfy shirt can do a better job.

31 Aug 2021

Durability of cellular immune memory to SARS-CoV-2 after mRNA vaccination

A recent study, available on the bioRxiv* preprint server, investigated the durability of cellular immune memory after mRNA vaccination against SARS-CoV-2 and whether booster jabs affect the durability of different immune response components. The study included testing for antibodies and cellular immune responses in covid patients and recovered individuals.

31 Aug 2021

SARS-CoV-2 animal origin: What we know so far

Scientists at the University of Glasgow Centre for Virus Research in the United Kingdom and the South China Agricultural University in Guangzhou, China, have shed light on the animal origin of SARS-CoV-2, tracing back to the first outbreak of the severe acute respiratory syndrome coronavirus (SARS-CoV), the infectious agent of the severe acute respiratory syndrome (SARS) in China in 2002 to 2003.

31 Aug 2021

Scientists identify potential biomarkers to predict COVID-19 outcomes

A team of scientists from the United States has recently examined the trajectory of early immune biomarkers in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. They have identified specific plasma proteins that can accurately predict the clinical and virological outcomes in SARS-CoV-2 infected patients. The study is currently available on the medRxiv* preprint server.

31 Aug 2021

Vaccinated individuals with breakthrough SARS-CoV-2 infection have much lower risk of hospitalization

A recent study conducted by a team of US-based scientists has revealed that unvaccinated individuals are 17-times more likely to be hospitalized due to severe coronavirus disease 2019 (COVID-19) compared to those vaccinated against the disease. The study is currently available on the medRxiv* preprint server.

31 Aug 2021

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

A team of investigators, led by Dr. Benjamin F. Mann, from Merck, USA have published a new study on the preprint server bioRxiv*. They have used a biochemical approach to control the glycosylation profile of the S protein receptor-binding domain (RBD) and to analyze the effect of different glycosylation patterns on receptor binding.

30 Aug 2021

New study to investigate treatment of respiratory infections in children with tracheostomy

Each year, approximately 4,000 children undergo a tracheostomy- the surgical placement of a breathing tube-due to respiratory or neuromuscular disorders or chronic disease progression.

30 Aug 2021

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Rescue breathing cardiopulmonary resuscitation (CPR) had superior neurological outcomes compared with compression-only CPR or no CPR at all in infants, children and adolescents, according to a new analysis published today in the Journal of the American College of Cardiology.

30 Aug 2021

Respiratory News and Research

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

Does SARS-CoV-2 infection protect against reinfection?

Researchers identify biomarkers for rare, serious complication in children with COVID-19

Anti-SARS-CoV-2 immunity induced by Pfizer/BioNTech vaccine may decline after 6 months

mRNA COVID-19 vaccines induce high antibody titers with significant neutralizing potency in saliva

Post-infection vaccination produces potent neutralizing antibodies against SARS-CoV-2 variants

J&J COVID-19 booster shot produces robust antibody response

Researchers develop adult lung organoids that represent all cell types

The tale of mRNA vaccines: Turning calamity into opportunity

Smart shirt made with carbon nanotube thread monitors the wearer’s heart rate

Durability of cellular immune memory to SARS-CoV-2 after mRNA vaccination

SARS-CoV-2 animal origin: What we know so far

Scientists identify potential biomarkers to predict COVID-19 outcomes

Vaccinated individuals with breakthrough SARS-CoV-2 infection have much lower risk of hospitalization

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

New study to investigate treatment of respiratory infections in children with tracheostomy

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

Researchers urge neurologists to actively encourage vaccinations for Parkinson's patients

How early interferon curbs SARS-CoV-2 infection

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From Discovery Biology to ELRIG Chair

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