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Multiple mechanisms at work in diabetes drug metformin

Metformin is the most commonly prescribed type 2 diabetes drug, yet scientists still do not fully know how it works to control blood sugar levels. In a collaborative effort, researchers from the Salk Institute, The Scripps Research Institute and Weill Cornell Medical College have used a novel technology to investigate why it functions so well.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

Vitamin E acetate and vaping-induced lung injury

In a report posted early online in the Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report (MMWR), scientists report that vaping products containing vitamin E acetate are apparently linked to the occurrence of lung injury in e-cigarette or vaping product users.

2 Dec 2019

Validation of new method for studying how different drugs interact in the body

Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body.

26 Nov 2019

Researchers discover molecular underpinnings of Alexander disease

Scientists have known that genetic mutations leading to the production of a defective protein called GFAP cause Alexander disease (AxD), a debilitating neurodegenerative condition that can present during infancy, adolescence, or adulthood.

21 Nov 2019

Researchers discover a peptide involved in both migraine and opioid-overuse pain

About 10% of the world population suffers from migraine headaches, according to the National Institute of Neurological Disorders and Stroke.

20 Nov 2019

Researchers detect photoinitiators in human breast milk

Photoinitators (PIs) are compounds used in the ink of many types of food packaging. The substances have been shown to migrate into food and, when consumed, show up in human blood serum.

20 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Life Sciences Mass Spectrometry 20 Nov 2019

Proteomics & DIA Mass Spectrometry in Neurodegenerative Disease Research

News-Medical Life Sciences spoke to Nicholas Dupuis from Biognosys about proteomics & DIA mass spectrometry in neurodegenerative disease research.

From Biognosys 19 Nov 2019

Nicotine delivery different for different e-cigarettes finds study

A new study from Penn State College of Medicine researchers has shown that different electronic cigarettes or “electronic nicotine delivery system (ENDS)” have different rates of nicotine delivery to the users. Most popular brand of e-cigarettes JUUL for example has been found to deliver more nicotine at a faster rate compared to other brands.

17 Nov 2019

Popular pod-based electronic cigarette can deliver more nicotine at faster rate than others

When it comes to nicotine delivery, not all electronic cigarettes are created equally, according to Penn State researchers. New research from Penn State College of Medicine shows that JUUL, a popular pod-based electronic cigarette, can deliver more nicotine at a faster rate than most other types of electronic cigarettes that have been studied.

15 Nov 2019

'Smart toilets' may work as real-time method of monitoring health

Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity - the humble toilet - may have potential to outperform them all.

13 Nov 2019

New tool could help detect smaller concentrations of drug powders

In 2017, more than 28,000 cases of fatal overdoses in the United States involved fentanyl. Just a pinch of the synthetic opioid, estimated to be 100 times stronger than morphine, can be lethal.

12 Nov 2019

Fingerprint sampling could help police distinguish between drug users and non-users

Researchers have developed a tool that can determine whether someone has used heroin, even if they have washed their hands.

11 Nov 2019

Leading researchers attend 3rd Annual Postnova Analytics FFF User Meeting

The 3rd Annual Postnova Analytics Field Flow Fractionation User Meeting was recently held on October 4, 2019 in Boston, MA (USA).

From Postnova Analytics 11 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Botanical product kratom may cause liver toxicity and injury, study finds

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that kratom, a popular and widely available product, may cause liver toxicity and severe liver injury.

10 Nov 2019

Study uncovers how cells 'forget their past' while developing into a specific cell

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’.

7 Nov 2019

Researchers analyze levels of spicy compounds in chili peppers during ripening

Anyone who has tasted a hot chili pepper has felt the burn of capsaicinoids, the compounds that give peppers their spiciness, as well as possible health benefits.

7 Nov 2019

Signs of frailty could be identified through a new assessment

Signs of frailty, and the risks it brings, could be identified in young and old people alike through a new assessment developed in a study led by researchers at the University of Strathclyde.

5 Nov 2019