Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

Novel neutralizing antibodies targeting SARS-CoV-2 N-terminal domain discovered

A new study by US-based researchers shows the presence of protective antibodies that target the N-terminal domain (NTD) of the spike instead of the spike receptor-binding domain (RBD).

22 Jan 2021

How have new SARS-CoV-2 strains become more transmissible?

A new study discusses the effect of specific mutations on the sensitivity of SARS-CoV-2's spike protein to elastase, and on the intramolecular conformational changes.

22 Jan 2021

Researchers update automated computation tool for SARS-CoV-2 genome analysis

Researchers updated a previous version of an automated tool to include SARS-CoV-2 genome analysis. Genome analysis using the freely available software could help track the evolution of the virus and promptly identify variants that increase viral transmission or virulence.

22 Jan 2021

SARS-CoV-2’s nonstructural proteins dysregulate immune responses, study finds

Researchers provide an overview of SARS-CoV-2 and its life cycle pathways, addressing the functional changes in the viral proteins, providing important strategic clues to help that may help in the ongoing development of therapies against COVID-19.

22 Jan 2021

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

A new study of Type 2 diabetes in Japanese populations has uncovered a previously uncharacterized genetic variant that puts male carriers at greater risk for the disease, as well as the mechanism by which it does so.

21 Jan 2021

New data on impact of spike mutations and B117 UK variant on neutralization by mAbs and sera

A recent paper by British and Dutch scientists, currently available on the bioRxiv* preprint server, shows that the neutralizing activity of monoclonal antibodies can be dramatically reduced by mutations of the SARS-CoV-2 spike glycoprotein – unlike polyclonal antibodies generated after natural infection that remain active regardless of any introduced amino acid changes.

21 Jan 2021

Vegan diet has a broad effect on children's metabolism, study reveals

University of Helsinki researchers report a comprehensive pilot study on the metabolic effects of full vegan diet on young children.

21 Jan 2021

South African SARS-CoV-2 variant escapes antibody neutralization

Researchers in South Africa have conducted a study showing that the novel 501Y.V2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in the country is able to escape the neutralizing antibodies that are elicited by previously circulating strains of the virus.

20 Jan 2021

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

Can metabolic biomarkers help clinicians stratify adverse outcome risk in COVID-19 patients?

A recent study describes the alterations in lipids and other parameters that define the state of dysfunctional metabolism in acute COVID-19 illness.

20 Jan 2021

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Researchers develop a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the SARS-CoV-2 spike protein – something which could inform future therapeutic research.

20 Jan 2021

Mapping antibody reactivity in COVID-19 patients by using multi-coronavirus protein microarray

In an exciting, state-of-the-art study currently available on the medRxiv* preprint server, US researchers created a multi-coronavirus protein microarray containing full-length proteins, peptide libraries, and overlapping protein fragments from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as four other human coronaviruses.

19 Jan 2021

Which SARS-CoV-2 mutations can potentially evade antibody recognition?

A team of US-based researchers has systematically identified SARS-CoV-2 mutations that could potentially evade neutralizing antibodies produced by the current vaccine candidates.

19 Jan 2021

Inflammation may contribute to the persistence of C. diff infection, shows study

A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and providing nutrients that enable C. diff to thrive.

19 Jan 2021

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Recently researchers from the United States reported the results of a SARS‐CoV‐2 genomic surveillance conducted between April 2020 and January 2021 in Columbus, Ohio. Their work is released as a preprint on the bioRxiv server.

18 Jan 2021

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

One new SARS-CoV-2 variant of concern, called 202012/01, started to spread in England in late October. A new study published on the pre-print server medRxiv found that 60 percent of daily COVID-19 cases screened by the Alderley Park Lighthouse Labs were tied to 202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1. This suggests a rapid spread of the new variant across the country.

18 Jan 2021

Study reveals new way to target cancer’s nutritional needs

Scientists discover a way to target cancer’s nutritional needs, which could lead to a new way to treat the disease, according to a study published in Nature Communications today (Thursday).

18 Jan 2021

New SARS-CoV-2 variant emerges in the U.S.

Even as the rollout of vaccines all over the world brings a glimmer of hope that the current coronavirus disease 2019 (COVID-19) pandemic may end in the near future, new variants continue to emerge, some with the potential to escape vaccine-induced or therapeutic antibodies. Now, a new preprint research paper published on the bioRxiv server describes a new American variant that may have become the dominant strain in the USA.

18 Jan 2021

Certain snakes evolve a unique genetic trick to avoid venomous snake-eating snakes

Certain snakes have evolved a unique genetic trick to avoid being eaten by venomous snakes, according to University of Queensland research.

15 Jan 2021

Severe COVID-19 linked to genetic make-up of both host and virus, say researchers

A recent study conducted by a team of international scientists has revealed that the infectivity and pathogenicity of SARS-CoV-2 strongly depend on the genetic background of both the virus and the host.

15 Jan 2021

Amino Acid News and Research

Further Reading

Novel neutralizing antibodies targeting SARS-CoV-2 N-terminal domain discovered

How have new SARS-CoV-2 strains become more transmissible?

Researchers update automated computation tool for SARS-CoV-2 genome analysis

SARS-CoV-2’s nonstructural proteins dysregulate immune responses, study finds

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

New data on impact of spike mutations and B117 UK variant on neutralization by mAbs and sera

Vegan diet has a broad effect on children's metabolism, study reveals

South African SARS-CoV-2 variant escapes antibody neutralization

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

Can metabolic biomarkers help clinicians stratify adverse outcome risk in COVID-19 patients?

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Mapping antibody reactivity in COVID-19 patients by using multi-coronavirus protein microarray

Which SARS-CoV-2 mutations can potentially evade antibody recognition?

Inflammation may contribute to the persistence of C. diff infection, shows study

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

Study reveals new way to target cancer’s nutritional needs

New SARS-CoV-2 variant emerges in the U.S.

Certain snakes evolve a unique genetic trick to avoid venomous snake-eating snakes

Severe COVID-19 linked to genetic make-up of both host and virus, say researchers

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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