Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Hippocampal role in psychosis bolstered

Reduced hippocampal volumes exist in patients across the psychosis spectrum, shows the latest report from the B-SNIP study.

21 May 2014

New compound restores learning, memory and other symptoms of AD in mice

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease.

21 May 2014

New cognitive test determines memory impairments due to AD and normal aging

Researchers have developed a new cognitive test that can better determine whether memory impairments are due to very mild Alzheimer's disease or the normal aging process.

21 May 2014

Global scientists to discuss latest findings on diagnosis, causes and treatments of ASD

The International Society for Autism Research (INSAR), a scientific and professional organization devoted to advancing knowledge about autism spectrum disorders, convened more than 1700 researchers, delegates, autism specialists and students from 40 countries for the 13th Annual International Meeting for Autism Research (IMFAR), the world's largest scientific gathering on autism research, from May 15 through May 17 at the Atlanta Marriott Marquis in Atlanta, GA.

15 May 2014

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

In 2008, researchers at the Perelman School of Medicine at the University of Pennsylvania showed that mutations in two proteins associated with familial Alzheimer's disease (FAD) disrupt the flow of calcium ions within neurons.

15 May 2014

People with longevity gene have improved brain skills

Scientists showed that people who have a variant of a longevity gene, called KLOTHO, have improved brain skills such as thinking, learning and memory regardless of their age, sex, or whether they have a genetic risk factor for Alzheimer's disease.

12 May 2014

Mice study shows specific energy source responsible for performing complex cognitive functions

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others.

9 May 2014

Finding has implications for understanding cognitive decline in degenerative diseases

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer's and multiple sclerosis.

8 May 2014

Hippocampus has critical role in mammalian learning

Theta-band activity in hippocampus after an event seems to be crucial for learning. A study at the University of Jyv-skyl- also proved that the absence of theta facilitated learning a simple task while training during theta had no effect on learning.

8 May 2014

Scientists identify key molecular switches that control age-related memory impairment

Even among the healthiest individuals, memory and cognitive abilities decline with age. This aspect of normal aging can affect an individual's quality of life and capability to live independently but the rate of decline is variable across individuals.

7 May 2014

Young blood can rejuvenate brains of old mice

Something - or some things - in the blood of young mice has the ability to restore mental capabilities in old mice, a new study by Stanford University School of Medicine investigators has found.

6 May 2014

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hippocampus.

6 May 2014

FABP5 protein enhances cognitive function

Case Western Reserve researchers have discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments.

5 May 2014

Mayo Clinic neuroscientists define subtype of Alzheimer's disease

Neuroscientists at Mayo Clinic in Florida have defined a subtype of Alzheimer's disease (AD) that they say is neither well recognized nor treated appropriately.

2 May 2014

Researchers identify genetic factors that contribute to ADHD in humans

The 60 trillion cells that comprise our bodies communicate constantly. Information travels when chemical compounds released by some cells are received by receptors in the membrane of another cell.

26 Apr 2014

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Alzheimer's disease is the first cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge on the cellular mechanisms which cause alterations in nerve transmissions and the loss of memory in the initial stages of the disease.

25 Apr 2014

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

A study of older adults at increased risk for Alzheimer's disease shows that moderate physical activity may protect brain health and stave off shrinkage of the hippocampus- the brain region responsible for memory and spatial orientation that is attacked first in Alzheimer's disease.

25 Apr 2014

TSRI scientists identify protein complex that plays critical role in learning and memory formation

Scientists from the Florida campus of The Scripps Research Institute have identified a protein complex that plays a critical but previously unknown role in learning and memory formation.

23 Apr 2014

UT Southwestern researchers identify potential new treatment for depression

Researchers at UT Southwestern Medical Center are making breakthroughs that could benefit people suffering from depression.

23 Apr 2014

Researchers devise new approach to treatment of Alzheimer's disease

A team of researchers from Columbia University Medical Center, Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating the potentially toxic byproduct amyloid-beta, which is thought to contribute to the development of Alzheimer's.

21 Apr 2014

Hippocampus News and Research

Further Reading

Hippocampal role in psychosis bolstered

New compound restores learning, memory and other symptoms of AD in mice

New cognitive test determines memory impairments due to AD and normal aging

Global scientists to discuss latest findings on diagnosis, causes and treatments of ASD

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

People with longevity gene have improved brain skills

Mice study shows specific energy source responsible for performing complex cognitive functions

Finding has implications for understanding cognitive decline in degenerative diseases

Hippocampus has critical role in mammalian learning

Scientists identify key molecular switches that control age-related memory impairment

Young blood can rejuvenate brains of old mice

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

FABP5 protein enhances cognitive function

Mayo Clinic neuroscientists define subtype of Alzheimer's disease

Researchers identify genetic factors that contribute to ADHD in humans

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

TSRI scientists identify protein complex that plays critical role in learning and memory formation

UT Southwestern researchers identify potential new treatment for depression

Researchers devise new approach to treatment of Alzheimer's disease

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