Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Research forum to present results of novel anti-obesity medications

Rhythm Pharmaceuticals and Novartis will present findings from the latest stages of clinical evaluation of new anti-obesity medications during a special late-breaking research forum titled "Emerging Pharmacological Anti-obesity Therapies."

31 Oct 2019

New discovery paves way for better treatment of diabetes

Insulin, a hormone essential for regulating blood sugar and lipids, is normally produced by pancreatic β cells. In many people with diabetes, however, pancreatic cells are not (or no longer) functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections.

16 Oct 2019

Experts discuss sex-specific sensitivity to key blood pressure hormone

Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body.

4 Oct 2019

Researchers identify new genetic signals for regulation of infant growth

Researchers at the University of Bergen in Norway have identified new genetic signals for the regulation of how infants grow. This may be a crucial step in the fight against growth-related diseases.

1 Oct 2019

Johns Hopkins researchers identify new way to lower blood pressure in obese patients

There's no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure.

From Johns Hopkins Medicine 26 Sep 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

'Weight cycling' may provide metabolic health benefits

Repeatedly losing and regaining weight may lead to improved insulin levels and lower body fat percentages in the long term, even during weight regain phases.

10 Sep 2019

Fatty food changes the brain to affect homeostasis and metabolism

While we all know that eating fatty food pushes up our body weight, a new study now shows it also affects the way the brain keeps track of and corrects all metabolic irregularities in the body. Soon after tucking into a high-fat, high-carb meal – as soon as three days later – the hypothalamus shows inflammation.

10 Sep 2019

Genetic variants associated with adult obesity start playing a role during early childhood

Body mass index in infants, children and adults is influenced by different genetic factors that change as we age, according to a major new study.

5 Sep 2019

Overweight adolescents actually eat less when exposed to stressful events

People often react to stress by binging on sweets or fattening comfort foods, cravings fueled by the appetite-stimulating stress hormone cortisol.

3 Sep 2019

Maternal high-fat diet may slow learning ability in offspring, study suggests

In a bid to further explore how a mother-to-be's diet might affect her offspring's brain health, Johns Hopkins Medicine researchers have found that pregnant and nursing rats fed high fat diets have offspring that grow up to be slower than expected learners and that have persistently abnormal levels of the components needed for healthy brain development and metabolism.

From Johns Hopkins Medicine 28 Aug 2019

Intermittent fasting may regulate blood glucose levels even without weight loss

New research suggests that intermittent fasting, cycling through periods of normal eating and fasting may regulate blood sugar (glucose) levels even when accompanied by little-to-no weight loss.

17 Jul 2019

Metabolic enzyme tied to obesity and fatty liver disease

A team of researchers at the Clemson University found that Cyp2b gene, which metabolizes endo and xenobiotics, may be linked to age-onset obesity and dyslipidemia, especially in males.

11 Jul 2019

Maternal obesity may negatively affect children's lung development

Obesity during pregnancy may negatively affect children's lung development, according to new research. The study, published ahead of print in the American Journal of Physiology-;Lung Cellular and Molecular Physiology, was chosen as an APSselect article for July.

2 Jul 2019

New mutation discovered in the leptin gene

The global obesity epidemic is so far-reaching it now has an overarching name: globesity. Texas Biomed Staff Scientist Raul Bastarrachea, M.D., is part of a team that discovered a new mutation in the gene that regulates the key hormone suppressing hunger called leptin.

22 Jun 2019

New findings offer pathway for fight against non-alcoholic fatty liver disease

A research group from the Medical University of Vienna was able to decode the mechanism as to how the hormone Leptin stimulates the liver to export lipids and reduce the fat production in the liver.

21 Jun 2019

Yale researchers offer insight into the hunger hormone

In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and also suggest a potential strategy for developing future weight-loss treatments, they said.

19 Jun 2019