Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

St. John's wort and Echinacea increase activity of enzyme in the liver and intestine

St. John's wort and Echinacea, two widely-used herbal preparations, have been found to increase activity of a specific enzyme in the liver and intestine, an enzyme involved in the metabolization of roughly one in every four pharmaceutical drugs on the market today, reports a clinical pharmacologist at Indiana University School of Medicine.

11 Apr 2006

Regular use of COX-2 inhibitors may reduce the risk of breast cancer

Results from a new, five-year study show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by up to 71 percent and may offer similar benefit in the prevention of prostate, colon and lung cancers.

4 Apr 2006

Reaction to DTaP vaccine finds no help from ibuprofen, acetaminophen

A red splotch forms where most preschoolers get their fifth, and last, shot of the acellular diphtheria-tetanus-pertussis (DTaP) vaccine, and it can last a few days.

1 Mar 2006

Drugs formerly contraindicated for inflammatory bowel disease prove beneficial for pain relief

According to two studies published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, prescription painkillers are effective in easing the pain of patients with dormant inflammatory bowel disease (IBD) and are not likely to cause symptom flare-ups in IBD patients in remissions

12 Feb 2006

Regular use of COX-2 inhibitors reduces breast cancer risk

A case-control study published today in the open access journal BMC Cancer observed that daily use of selective COX-2 inhibitors, including celecoxib (Celebrex) and rofecoxib (Vioxx), was associated with a 71% reduction in the risk of breast cancer.

2 Feb 2006

It's true! study confirms that Glucosamine and Chondroitin relieve arthritis pain

The millions of Osteoarthritis sufferers in the world will welcome the good news that a new study has confirmed that the dietary supplements glucosamine and chondroitin provide pain relief.

15 Nov 2005

Use of traction to help treat low back pain has no benefit

"Traction was introduced before it was properly evaluated in high-quality randomized trials, and as an intervention is already part of usual practice,” said lead author Judy M.A. Clarke, M.D. “It is hard to convince health care providers not to use it."

10 Nov 2005

People living in predominantly minority areas face significant barriers to accessing pain medication

Chronic pain is a condition that affects one in five Americans without regard for their race or finances. But a new study finds that minorities and people with low incomes have less access than high-income white people to the medications that will help them endure their pain.

10 Oct 2005

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention, according to a study in the October issue of Archives of General Psychiatry.

4 Oct 2005

Taking aspirin longterm could reduce colorectal cancer risk

According to new report from the Nurses' Health Study (NHS), regular, long-term aspirin use can significantly reduce the risk of colorectal cancer.

24 Aug 2005

Aspirin use can significantly reduce the risk of colorectal cancer

A new report from the Nurse's Health Study finds that regular, long-term aspirin use can significantly reduce the risk of colorectal cancer, as suggested by several earlier studies.

23 Aug 2005

Common non-aspirin painkillers linked to high blood pressure in women

Women who consume higher doses of non-aspirin painkillers are much more likely to develop high blood pressure than women who do not use them, according to research reported in Hypertension: Journal of the American Heart Association.

17 Aug 2005

New study shows even non-prescription painkillers raise blood pressure in women

According to a new U.S. study women who take higher doses of common, over-the-counter painkillers, such as Ibuprofen and even Tylenol, have higher blood pressure than women who do not.

16 Aug 2005

Chronic use of nitroglycerin for chest pain could lead to mitochondrial damage

Definitive evidence to explain how the drug nitroglycerin relieves chest pain has resulted from a new study by Howard Hughes Medical Institute investigators at Duke University Medical Center. Nitroglycerin relaxes blood vessels to boost blood flow, yet the mechanism by which the drug works has remained a matter of scientific controversy.

16 Aug 2005

Acetaminophen, when taken as directed, is safe for patients with liver disease

Contrary to common perception, clinical data demonstrate that acetaminophen is an appropriate pain relief choice for patients with chronic liver disease. According to a systematic literature review of the data, which is published in the current issue of the American Journal of Therapeutics, there is no evidence that acetaminophen at therapeutic doses aggravates liver disease.

26 Jul 2005

Colon cancer patients who took aspirin regularly fared better after surgery

Colon cancer patients who took aspirin regularly fared better after surgery, reducing their risk of disease recurrence and death by half compared to non-users, researchers will report at the annual meeting of the American Society of Clinical Oncology.

16 May 2005

Paracetamol linked to asthma and reduced lung function

Scientists now suspect that regular use of the painkiller paracetamol, is linked with higher rates of asthma and chronic obstructive pulmonary disease (COPD) and reduced lung function.

3 May 2005

NSAIDs okay for tonsillectomy, new study finds

When children have their tonsils removed, nonsteroidal anti-inflammatory drugs can be used for pain relief with no significant increase in bleeding and with less nausea and vomiting, according to a systematic review of current evidence.

19 Apr 2005

Drug that reduces the pain of fibromyalgia and improves sleep

A study of a drug that reduces the pain of fibromyalgia and improves sleep is published by a University of Kentucky physician in the peer-reviewed journal, Arthritis & Rheumatism.

12 Apr 2005

High-rise homes have the highest levels of cockroach allergens

Roaches like to live high in the sky in places like Chicago, New York City and the Bronx, according to a recent study in the Journal of Allergy and Clinical Immunology. The study, conducted by an allergist affiliated with Children's Medical Center Dallas, found high-rise homes in Northeastern cities had the highest levels of cockroach allergens -- leading to a higher incidence of asthmatic episodes.

30 Mar 2005