Anesthetics News and Research

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Lighter sedation during spinal anesthesia reduces postoperative delirium in elderly patients

A recent study, published in the January issue of Mayo Clinic Proceedings, demonstrates that in elderly patients undergoing hip fracture repair under spinal anesthesia with propofol sedation, the prevalence of delirium can be decreased by 50 percent with light sedation, compared to deep sedation.

19 Jan 2010

Study on cyanobacteria helps understand anesthetic actions

Experiments in one of the oldest forms of life on Earth are helping to answer basic questions about how general anesthesia works, according to a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

23 Dec 2009

Low doses of lidocaine given intravenously help control pain after ambulatory surgery procedures

Although lidocaine is most often used as a local anesthetic, low doses of lidocaine given intravenously can help to control pain after common ambulatory surgery procedures, suggests a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

10 Dec 2009

Milestone Scientific announces new joint venture with two PRC pharmaceutical companies

Milestone Scientific Inc., the recognized leader in advanced injection technologies, today announced that it had entered into a joint venture with China National Medicines Corporation Ltd. (d/b/a "Sinopharm") and Yichang Humanwell Pharmaceutical Co. Ltd., both incorporated in the People's Republic of China (the "PRC"), to develop orthopedic and epidural drug delivery instruments.

3 Dec 2009

J&JPRD submits an NDA for tapentadol ER tablets

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. announced today that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for tapentadol extended release (ER) tablets, an investigational oral analgesic for the management of moderate to severe chronic pain in patients 18 years of age or older.

2 Dec 2009

Mechanism blocking HIV-1 from entering cells identified

Publishing in PLoS Pathogens, researchers at from the Kimmel Cancer Center at Jefferson have found a novel mechanism by which drugs block HIV-1 from entering host cells.

1 Dec 2009

Neurometrix reports financial results for the third quarter of 2009

NeuroMetrix, Inc., a health care company transforming patient care through neurotechnology, today announced its third quarter financial results.

5 Nov 2009

Financial results for third-quarter 2009 announced by Combinatorx

CombinatoRx, Incorporated today reported financial results for the third quarter ended September 30, 2009.

3 Nov 2009

Study: General anesthesia can cause brain injury in immature rats

Studies by researchers at Wake Forest University School of Medicine have shown that blocking the NMDA receptor in immature rats leads to profound, rapid brain injury and disruption of auditory function as the animals mature.

23 Oct 2009

Positive results from Phase 2 clinical trial of ARX-03 announced

AcelRx Pharmaceuticals, Inc. today announced positive results from a Phase 2 clinical trial of ARX-03, a proprietary sublingual dosage form combining an opioid, sufentanil, with a benzodiazepine, triazolam.

23 Oct 2009

GE Healthcare announces FDA clearance of CARESCAPE Monitor B850

GE Healthcare today announced the FDA-cleared CARESCAPE™ Monitor B850, which provides caregivers with a unique level of integration between patient monitoring data and hospital information systems. Unlike traditional patient monitors, CARESCAPE Monitor B850 directly links hospital networks, electronic medical records (EMRs), diagnostic images, lab results and third-party devices with real-time patient monitoring data, to support efficient clinical decision-making.

6 Oct 2009

Covidien receives 510(k) clearance to market Mallinckrodt Taperguard Evac endotracheal tube

Covidien, a leading global provider of healthcare products and recognized innovator in mechanical ventilation and respiratory care devices, today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its Mallinckrodt™ TaperGuard™ Evac endotracheal tube.

1 Oct 2009

Covidien to acquire Aspect Medical Systems

Covidien (NYSE: COV) and Aspect Medical Systems, Inc. (NASDAQ: ASPM) today announced that Covidien has reached a definitive agreement to acquire Aspect, a global market leader in brain monitoring technology.

28 Sep 2009

Research study sheds light on mechanisms of pain alteration in infancy and adolescence

Scientists at Georgia State University have uncovered the mechanisms of how pain in infancy alters how the brain processes pain in adulthood.

26 Sep 2009

NASDAQ halts trading in CombinatoRx's common stock

CombinatoRx, Incorporated (NASDAQ: CRXX) announced that NASDAQ has halted trading in the Company’s common stock today.

23 Sep 2009

FDA committees to review Neuromed’s NDA for Exalgo

CombinatoRx, Incorporated (NASDAQ: CRXX) and Neuromed Pharmaceuticals, Inc., a privately-held biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has posted on its website briefing documents for the September 23, 2009 joint meeting of its Anesthetics and Life Support Advisory Committee and its Drug Safety and Risk Management Advisory Committee.

23 Sep 2009

King Pharmaceuticals achieves milestone: Announces commercial availability of EMBEDA

King Pharmaceuticals(R), Inc. (NYSE: KG) today announced a true milestone as it marks the first commercial availability for EMBEDA(TM) (morphine sulfate and naltrexone hydrochloride) Extended Release Capsules, a long-acting Schedule II opioid analgesic for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time.

21 Sep 2009

Wisconsin researchers identify the genetic region responsible for cardiovascular collapse during anesthesia

Researchers at The Medical College of Wisconsin in Milwaukee have identified the genetic region in rats responsible for cardiovascular collapse during anesthesia. While it is well known that people have different cardiovascular sensitivity to anesthesia causing some to collapse even when low doses are administered, the mechanism responsible for this susceptibility is not clear.

11 Sep 2009

NeuroMetrix completes private placement of common stock and warrants

NeuroMetrix, Inc., today announced that it has completed its private placement of common stock and warrants. Gross proceeds from the offering were approximately $18.7 million.

11 Sep 2009

NeuroMetrix to purchase $18.68 million of its common stock

NeuroMetrix, Inc., a healthcare company transforming patient care through neurotechnology, today announced that it has obtained commitments from institutional investors to purchase approximately $18.68 million of its common stock in a private placement.

9 Sep 2009