Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

WASC accredits Cedars-Sinai PhD program in biomedical sciences and translational medicine

The Graduate Program in Biomedical Sciences and Translational Medicine at Cedars-Sinai has been accredited by the Western Association of Schools and Colleges, an affirmation that the PhD-awarding educational effort meets the most rigorous standards of higher learning.

25 Jul 2012

New combination therapy for TB shows promise in Phase II study

"Results from a groundbreaking trial of three drugs given in combination -- one of them completely new and one not yet licensed for this use -- killed more than 99 percent of patients' [tuberculosis (TB)] bacteria after two weeks of treatment," and the combination "appears to be equally effective on drug-resistant TB," the Guardian reports.

25 Jul 2012

Malaria misdiagnosis in parts of Asia

Substantial overdiagnosis and mistreatment of malaria is evident in south and central Asia, warns a study published on bmj.com today.

25 Jul 2012

Novel combination drug regimen could be more effective than existing treatments for TB

A novel approach to discover the first new tuberculosis (TB) combination drug regimen cleared a major hurdle when Phase II clinical trial results found it could kill more than 99 percent of patients' TB bacteria within two weeks and could be more effective than existing treatments, according to a study published today in the Lancet.

24 Jul 2012

TB combination drug trials progress

A novel approach to discover the first new tuberculosis (TB) combination drug regimen cleared a major hurdle when Phase II clinical trial results found it could kill more than 99 percent of patients’ TB bacteria within two weeks and could be more effective than existing treatments, according to a study published today in the Lancet. These results add to a growing body of evidence that the new regimen could reduce treatment by more than a year for some patients.

24 Jul 2012

Experts examine host recognition of Staphylococcus and E.coli bacteria

We are surrounded by bacteria, viruses, fungi and parasites. The fact that we nevertheless do not fall prey to infections is thanks to certain cellular sensor molecules such as toll-like receptors (TLR), which recognize the molecular structure of pathogens and intercede by ensuring an often completely unnoticeable elimination of the invaders. Their immune-activating abilities were only detected in 1998, a discovery which was awarded with the Nobel Prize

21 Jul 2012

New class of chemically produced antimicrobial agents could become future infection treatment alternative

The World Health Organization (WHO) has named antimicrobial resistance one of the most important threats to human health. We therefore need to find new compounds that can be used as future alternatives to conventional antibiotics.

20 Jul 2012

Chest X-ray prevents excess antibiotic use in childhood pneumonia

Use of a chest X-ray as well as traditional clinical parameters to diagnose childhood pneumonia can prevent overdiagnosis and unnecessary use of antibiotics, say researchers.

16 Jul 2012

Researchers discover HVEM’s unknown role in fighting off E. coli infections

Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the world. But the research community is gaining ground. In a major finding, published today in the scientific journal Nature, researchers from the La Jolla Institute for Allergy & Immunology have discovered a molecule's previously unknown role in fighting off E. coli and other bacterial infections, a discovery that could lead to new ways to protect people from these dangerous microorganisms.

16 Jul 2012

EU-funded researchers develop new antimicrobial resistance monitoring solution

Every year hundreds of thousands of people die because of infections that have become resistant to treatment. A new data-mining, clinical monitoring and decision-support system, developed by EU-funded researchers, offers a powerful new weapon in the war on resistance to antibiotics.

14 Jul 2012

Early surgery best for infective endocarditis

Compared with conventional treatment, early surgery for patients with infective endocarditis and large vegetations significantly reduces the risk for death or embolic events by reducing the risk for systemic embolism, show results from a randomized trial.

12 Jul 2012

Viewpoints: Trouble keeping health costs down; Ignagni says law needs some revisions; Coverage is like clean water

Now that the Supreme Court has provided legal certainty on the recent healthcare reform law, the nation must turn its attention to affordability. While the law expands coverage to millions of Americans, a goal health plans have long supported, major provisions of the law need to be changed to avoid significant cost increases for consumers and employers.

12 Jul 2012

Chest X-ray prevents excess antibiotic use in childhood pneumonia

Use of a chest X-ray as well as traditional clinical parameters to diagnose childhood pneumonia can prevent overdiagnosis and unnecessary use of antibiotics, say researchers.

10 Jul 2012

Peritoneal dialysis patients who live remotely face high peritonitis risk

Patients with renal disease who live more than 100 km from their nearest peritoneal dialysis unit face a higher risk for peritonitis, particularly with Staphylococcus aureus, than their peers who live closer, results of a large Australian study show.

10 Jul 2012

Researchers develop new silk-based stabilizer for vaccines and antibiotics

Researchers funded by the National Institutes of Health have developed a new silk-based stabilizer that, in the laboratory, kept some vaccines and antibiotics stable up to temperatures of 140 degrees Fahrenheit.

10 Jul 2012

ASM’s mBio achieves significant increase in impact factor

Less than two years after publishing its first issue, the online open-access journal mBio- is now ranked among the top 20 highest-impact microbiology journals according to Thomson Reuters, which has just released its Journal Citation Reports for 2011.

10 Jul 2012

PCV13 offers best overall protection from CAP in young children

Researchers have identified a pneumococcal conjugate vaccine that is effective for treating bacteremic pneumococcal community-acquired pneumonia in children aged 5 years or younger.

9 Jul 2012

New research approach can help predict the 'tenability' of antibiotics

Research by Wageningen University, part of Wageningen UR, has shown that the development of bacteria with resistance against the antibiotic cefotaxime occurs more often and more predictably than was previously assumed. Bacterial populations were found to have many mutations that increase resistance and therefore have a negative effect on public health.

4 Jul 2012

Raising vitamin D concentrations reduces risk of HAIs among hospital patients

A paper recently published in Dermato-Endocrinology indicates that raising vitamin D concentrations among hospital patients has the potential to greatly reduce the risk of hospital-acquired infections.

4 Jul 2012

IRIN examines antibiotic resistance, efforts to discover new drugs

IRIN examines a global increase in resistance to antibiotics, writing, "Almost one in every five deaths worldwide occurs as a result of infection, but many bacterial illnesses will become incurable as the efficacy of current antibiotic drugs wanes, according to the World Health Organization (WHO)."

3 Jul 2012