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Innovative immunotherapy targets rare melanoma subtypes

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.

16 Feb 2024

City of Hope cures oldest person of blood cancer and achieves HIV remission

City of Hope, one of the largest cancer research and treatment organizations in the United States, treated the oldest person to be cured of a blood cancer and then achieve remission for HIV after receiving a blood stem cell transplant from a donor with a rare genetic mutation.

15 Feb 2024

Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

15 Feb 2024

Maternal mRNA COVID-19 vaccination shields infants for six months

Women who receive an mRNA-based COVID-19 vaccination or booster during pregnancy can provide their infants with strong protection against symptomatic COVID-19 infection for at least six months after birth, according to a study from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

15 Feb 2024

Managing migraines and menopausal symptoms to reduce cardiovascular risks in middle-aged women

14 Feb 2024

Advanced melanoma survival rates improve significantly from 2013 to 2019, Dutch study finds

The change in overall survival (OS) among advanced melanoma patients diagnosed between 2013 and 2021.

14 Feb 2024

Home-administered COVID-19 rapid antigen tests show comparable accuracy to clinician-performed tests

In a study involving nearly 1,000 patients seen at the Baltimore Convention Center Field Hospital (BCCFH) during a five-month period in 2022 -; researchers at Johns Hopkins Medicine, the University of Maryland School of Medicine and five other collaborators report that a rapid antigen test (RAT) for detecting SARS-CoV-2, the virus that causes COVID-19, can be used at home with accuracy comparable to the same test being administered by a health care professional.

13 Feb 2024

Hand-held biosensor detects breast cancer biomarkers from saliva

Breast cancer is on the rise, but new tools for early detection could save lives.

13 Feb 2024

Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024

Promising new CMV vaccine shows stronger immune response

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

12 Feb 2024

CDC releases new syphilis testing guidelines to combat rising cases

The CDC's new guidelines in the Morbidity and Mortality Weekly Report outline comprehensive testing protocols for syphilis diagnosis, emphasizing the combined use of nontreponemal and treponemal tests to improve detection and management of the disease in the U.S.

11 Feb 2024

MHRA authorizes COVID-19 vaccines: Comirnaty and Nuvaxovid gain approvals

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a change to the license of the Comirnaty Omicron XBB.1.5 30 micrograms/dose (single-dose vials) after it was found to meet the UK regulator's standards of safety, quality and effectiveness.

9 Feb 2024

ANU discovery provides new insight into how the immune system fights malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

8 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

Experimental mRNA vaccine against CMV elicits promising immune responses

7 Feb 2024

Prior Zika infection ups risk of severe dengue, study finds

A study led by Brazilian researchers shows that people who have had zika run a higher risk of subsequently having severe dengue and being hospitalized.

7 Feb 2024

Interdisciplinary dream team receives $3 million grant to revolutionize Alzheimer's diagnosis

What do a synthetic chemist, a medical imaging expert, and a neurologist have in common? They're coming together in the Biomedical Imaging Center at the Beckman Institute for Advanced Science and Technology to develop better diagnostic tools and imaging agents to detect early-stage Alzheimer's disease and other neurodegenerative diseases.

6 Feb 2024

Scientists pinpoint two cell-surface proteins that partner to spur cancer cell growth

Scientists at City of Hope®, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. The study was published in Nature Structural & Molecular Biology today.

5 Feb 2024

Revvity showcases cutting-edge solutions at SLAS2024

Revvity presents its continued commitment to expanding the boundaries of human potential through science.

From Revvity 5 Feb 2024

New method helps to reliably distinguish surgical meshes from normal bodily tissue

Prototypes of surgical meshes that can be seen clearly on CT scans have been developed by researchers at UCL for the first time, promising to increase the speed at which problems can be diagnosed and resolved.

5 Feb 2024