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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.
TSRI scientists develop new strategy to design potential HIV vaccine candidates

TSRI scientists develop new strategy to design potential HIV vaccine candidates

Want to catch a criminal? Show a mugshot on the news. Want to stop HIV infections? Get the immune system to recognize and attack the virus's tell-tale structure. That's part of the basic approach behind efforts at The Scripps Research Institute to design an AIDS vaccine. [More]
Home test using paper strips could help detect cancer, malaria

Home test using paper strips could help detect cancer, malaria

What if testing yourself for cancer or other diseases were as easy as testing your blood sugar or taking a home pregnancy test? In a few years, it might be. [More]
Two vaccine candidates provide complete protection against ZIKV infection in mice

Two vaccine candidates provide complete protection against ZIKV infection in mice

The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects. [More]
Deficiency in NMD could cause inflammatory myofibroblastic tumors

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Inflammatory myofibroblastic tumors (IMTs) — masses of immune cells— are benign, but poorly understood. Current IMT treatments often have side effects and surgery is sometimes not an option due to the tumor's proximity to vital organs. [More]
Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Scientists from the Institut Pasteur and the CNRS, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. [More]
Pre-existing dengue antibodies can intensify Zika virus infection

Pre-existing dengue antibodies can intensify Zika virus infection

Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London. [More]
Scientists streamline total synthesis of uncialamycin drug

Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin. [More]
'Simple' model predicts PegIFN response in chronic HBV

'Simple' model predicts PegIFN response in chronic HBV

Chinese researchers have developed a scoring system based on hepatitis B virus-related clinical parameters to predict response to pegylated-interferon in chronic HBV patients. [More]
Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Rituximab may be an attractive treatment option for patients with relapsing-remitting multiple sclerosis, suggest phase II study findings showing its efficacy in controlling inflammatory activity. [More]
Salvage inotuzumab ozogamicin improves ALL outcomes

Salvage inotuzumab ozogamicin improves ALL outcomes

Compared with standard chemotherapy, treatment with inotuzumab ozogamicin increases the rate of complete remission and allows a higher proportion of patients with relapsed or refractory acute lymphoblastic leukaemia to subsequently receive stem-cell transplantation, research suggests. [More]
Researchers seek to develop novel antibody to treat glioblastoma

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors. [More]
New CAR-based therapy using combined cancer target could be effective for solid tumors

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells. [More]
Researchers aim to improve medical treatment for people with insect venom allergy

Researchers aim to improve medical treatment for people with insect venom allergy

A team of researchers has elucidated individual profiles of allergy reactivity in patients that are not protected after treatment with immunotherapy. The aim is to improve medical treatment of people who are allergic to insect stings. [More]
Rice University researchers synthesize new anti-cancer agent

Rice University researchers synthesize new anti-cancer agent

Rice University scientists have synthesized a novel anti-cancer agent, Thailanstatin A, which was originally isolated from a bacterial species collected in Thailand. [More]
People with higher levels of IgG/IgM antibodies less likely to have heart attack

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Measuring antibody levels in the blood could be used to detect a person's heart attack risk after researchers, part-funded by the British Heart Foundation, discovered that higher levels of these antibodies are linked to a lower heart attack risk. [More]
S1P1R variation may cause differential patient responses to fingolimod treatment

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1-phosphate (S1P), which is linked to MS pathogenesis. [More]
New FcMBL-based pathogen-detecting assay could rapidly detect systemic infections

New FcMBL-based pathogen-detecting assay could rapidly detect systemic infections

To date, there are no methods that can quickly and accurately detect pathogens in blood to allow the diagnosis of systemic bloodstream infections that can lead to life-threatening sepsis. [More]
T memory cells with naive phenotype can help boost immunity in older adults

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system. [More]
Nearly half of newly-infected HIV patients experience neurologic issues

Nearly half of newly-infected HIV patients experience neurologic issues

A team led by researchers from UCSF and Yale has found that half of people newly infected with HIV experience neurologic issues. These neurologic findings are generally not severe and usually resolve after participants started anti-retroviral therapy. [More]
Novel radioimmunotherapy may help cure colorectal cancer

Novel radioimmunotherapy may help cure colorectal cancer

An emerging cancer therapy has colorectal tumors surrounded. Presenters at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging are unveiling a novel radioimmunotherapy that combines a cancer-seeking antibody with potent radionuclide agents, resulting in complete remission of colorectal cancer in mouse models. [More]
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