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Touchlight, Cancer Research UK and University of Southampton team up to develop DNA cancer vaccine

Cancer Research UK, the University of Southampton and Touchlight Genetics, a London based biotechnology company, today (Wednesday) announce a new clinical development partnership to progress a therapeutic DNA vaccine, TGL-100, into an early phase clinical trial targeting head and neck squamous cell carcinoma.

31 Jul 2020

New blood test can detect prostate cancer and confirm the stage of the disease

A new blood test developed by scientists and clinicians is able to detect the presence of prostate cancer and confirm how advanced it is.

30 Jul 2020

Study finds synthetic neutralizing/enhancing antibodies to SARS-CoV-2

A new study published on the preprint server bioRxiv in July 2020 reports the discovery of some antibody molecules that have powerful enhancing or neutralizing activity against the virus, in a library of synthetic antibodies. These hold the promise of being useful for the prevention or treatment of this illness.

30 Jul 2020

SARS-CoV-2 exposure five times more likely among Black and Hispanic pregnant women

Black and Hispanic pregnant women in Philadelphia are five times as likely as white and Asian women to have been exposed to the novel coronavirus, according to a new study led by Scott Hensley, PhD, an associate professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, and Karen Marie Puopolo, MD, PhD, an associate professor of Pediatrics and neonatologist at the Children's Hospital of Philadelphia. The study was published today in Science Immunology.

29 Jul 2020

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Experts warn that the world may see repeated waves of the COVID-19 pandemic. However, scientists around the world are working hard to create a protective vaccine or antiviral, which could help to reduce the number of deaths and cases the next time around.

29 Jul 2020

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

To better protect individuals serving on the front lines of battlefields or dealing with an event like the current COVID-19 health crisis or potential future pandemics, scientists at the University of Arizona College of Medicine - Phoenix are leading an effort to develop a device for easy, quick and accurate detection of pathogens and biological threats.

28 Jul 2020

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Today's Food and Drug Administration approval of the first CAR T-cell therapy for mantle cell lymphoma represents a key advance for patients with relapsed or treatment-resistant forms of the disease, say Dana-Farber Cancer Institute investigators who helped conduct the decisive clinical trial of the therapy.

24 Jul 2020

Researchers design new version of protein to develop COVID-19 vaccine

Responding to a need to quickly develop billions of doses of lifesaving COVID-19 vaccines, a scientific team at The University of Texas at Austin has successfully redesigned a key protein from the coronavirus, and the modification could enable much faster and more stable production of vaccines worldwide.

24 Jul 2020

Combining two immunotherapies into a single treatment found to be more effective

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer. But immunotherapies don't work in all patients, and researchers have been searching for ways to increase their effectiveness.

23 Jul 2020

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Scientists have uncovered the genomic signature to explain why 18F-FDG imaging performs better than PSMA-targeted imaging for prostate cancer patients with low or no expression of the prostate-specific membrane antigen (PSMA).

23 Jul 2020

Non-invasive algorithm predicts complications in patients following recovery from hepatitis C

The chronic viral inflammation of the liver that occurs in hepatitis C results in the formation of inflexible scar tissue in the form of fibrosis/cirrhosis of the liver. This impedes the flow of blood through the organ, with resulting hypertension in the portal vein.

23 Jul 2020

Neo-self antibody could be a major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases (RIMD) have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

Research could lead to more efficient cellular immunotherapies for advanced cancers

Adoptive cell transfer immunotherapy is one of the most promising new treatments for people with hard-to-treat cancers.

23 Jul 2020

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Avacta is pleased to announce that it has begun work with the UK government’s CONDOR program to evaluate and clinically validate the COVID-19 laboratory assay.

22 Jul 2020

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Avacta is pleased to announce that it has begun work with the UK government’s CONDOR program to evaluate and clinically validate the COVID-19 laboratory assay.

22 Jul 2020

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

A new study published on the preprint server medRxiv by a research group from the U.S. and Germany indicates that a novel BNT162b1 RNA-based vaccine against coronavirus disease (COVID-19) induces functional and proinflammatory T cell responses in almost all participants – marking another landmark achievement for this promising vaccine candidate.

21 Jul 2020

New assay improves detection of SARS-CoV-2 antibodies

Researchers at the University of California Santa Cruz have developed a new assay for the detection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that they say provides significant advantages over the techniques currently used.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

Oxford University and AstraZeneca to publish eagerly-anticipated COVID-19 trial results today

The coronavirus pandemic is still rapidly spreading across the globe, infecting more than 14.44 million people. With more than 188 countries and territories affected, scientists are racing to develop a vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

19 Jul 2020

Antigen News and Research

Touchlight, Cancer Research UK and University of Southampton team up to develop DNA cancer vaccine

New blood test can detect prostate cancer and confirm the stage of the disease

Study finds synthetic neutralizing/enhancing antibodies to SARS-CoV-2

SARS-CoV-2 exposure five times more likely among Black and Hispanic pregnant women

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Researchers design new version of protein to develop COVID-19 vaccine

Combining two immunotherapies into a single treatment found to be more effective

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Non-invasive algorithm predicts complications in patients following recovery from hepatitis C

Neo-self antibody could be a major cause of recurrent pregnancy loss

Research could lead to more efficient cellular immunotherapies for advanced cancers

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

New assay improves detection of SARS-CoV-2 antibodies

How immune cells switch to attack mode

Oxford University and AstraZeneca to publish eagerly-anticipated COVID-19 trial results today

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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