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People with exposure to paint or other solvents more likely to develop MS

People who have been exposed to paint, varnish and other solvents and who also carry genes that make them more susceptible to developing multiple sclerosis may be at much greater risk of developing the disease than people who have only the exposure to solvents or the MS genes, according to a study published in the July 3, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Jul 2018

Simple, accurate and reproducible assay to measure antibodies against malaria

Antibodies against multiple Plasmodium falciparum proteins (or antigens) can be measured using a simple, accurate and reproducible assay that requires very small amounts of blood.

3 Jul 2018

New method separates circulating tumor cells from blood samples using sound waves

Using sound waves, an international team of researchers has developed a gentle, contact-free method for separating circulating tumor cells from blood samples that is fast and efficient enough for clinical use.

3 Jul 2018

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

The California Institute for Regenerative Medicine board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy.

30 Jun 2018

Modified natural killer cells may be new player in CAR-T immunotherapies

Emerging CAR-T immunotherapies leverage modified versions of patient's T-cells to target and kill cancer cells.

29 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer.

25 Jun 2018

AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Advanced Accelerator Applications S.A., a Novartis company and leader in nuclear medicine theragnostics, today announced that the first patients have been dosed in two Phase I/II clinical studies of radiolabeled PSMA-R2, a urea-based ligand of Prostate-Specific Membrane Antigen, which is commonly expressed on prostate cancer cells.

22 Jun 2018

Scientists create universal assembly method to enhance cancer therapy and diagnostics

Biophysicists have developed a method for modifying the surface of micro- and nanoparticles — tiny structures measuring between a thousandth and a millionth of a millimeter — by covering them with biological molecules. Engineered in this way, the particles can serve as both therapeutic and diagnostic agents, delivering drugs to cancer cells.

19 Jun 2018

Researchers develop new approach to assess effectiveness of Men B vaccine

Researchers at the University of Leicester and Meningococcal Reference Unit have developed a new approach to assess the effectiveness of the Men B vaccine, Bexsero, against different strains that cause meningococcal meningitis and septicaemia.

18 Jun 2018

Studies provide insight into molecular changes prior to onset of arthritis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future novel diagnostics and early therapeutic interventions.

18 Jun 2018

Vitamin D and Diabetes: What You Need To Know

Dr. Cedric Garland discusses the results of a 12-year cohort study which showed that vitamin D3 can prevent type 1 diabetes in 80 percent of cases.

15 Jun 2018

Study provides insights into genetics underlying debilitating pediatric kidney disease

New research provides insights into the genetics underlying a debilitating kidney disease in children. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, could lead to new diagnostics and, ultimately, treatments.

14 Jun 2018

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Seattle Children's, with participating members Children's National Health System, BC Children's Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children's hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer.

12 Jun 2018

Research identifies new genetic variations that could indicate higher prostate cancer risk

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent.

12 Jun 2018

Customising T-cells for cancer immunotherapy

T-cell immunotherapy is revolutionizing cancer treatments. CD8+ T cells are modified to recognize tumor-specific antigens and induce an immune response.

12 Jun 2018

Researchers develop flexible "Plug and Play" technology to protect against emerging diseases

Researchers from GeoVax have developed a flexible "Plug and Play" technology platform that delivers single-dose vaccines that fully protect against emerging infectious diseases such as Zika, Lassa fever, and Ebola.

11 Jun 2018

More frequent post treatment monitoring does not improve survival in prostate cancer patients, finds study

African-American men with prostate cancer show stronger response to hormone therapy

African-American men with advanced prostate cancer might be more responsive than white men to an anti-androgen drug and steroids, according to a study led by Duke Cancer Institute researchers.

4 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

Antigen News and Research

People with exposure to paint or other solvents more likely to develop MS

Simple, accurate and reproducible assay to measure antibodies against malaria

New method separates circulating tumor cells from blood samples using sound waves

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

Modified natural killer cells may be new player in CAR-T immunotherapies

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Scientists create universal assembly method to enhance cancer therapy and diagnostics

Researchers develop new approach to assess effectiveness of Men B vaccine

Studies provide insight into molecular changes prior to onset of arthritis

Vitamin D and Diabetes: What You Need To Know

Study provides insights into genetics underlying debilitating pediatric kidney disease

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Research identifies new genetic variations that could indicate higher prostate cancer risk

Customising T-cells for cancer immunotherapy

Researchers develop flexible "Plug and Play" technology to protect against emerging diseases

More frequent post treatment monitoring does not improve survival in prostate cancer patients, finds study

African-American men with prostate cancer show stronger response to hormone therapy

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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