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Research shows new Zika virus vaccine that offers 100% protection in mice

Research presented by Farshad Guirakhoo, Ph.D., Chief Scientific Officer, GeoVax, Inc., at the ASM Microbe 2017 meeting showed a new Zika virus vaccine that gives 100% protection in mice.

5 Jun 2017

Researchers find new way to block type 1 diabetes

Researchers at The Jackson Laboratory, Cyteir Therapeutics and collaborating institutions have found a way to protect beta cells from destruction -- achieving a longtime, elusive goal that could lead to therapies preventing type 1 diabetes (T1D).

1 Jun 2017

Clinical trial uses small molecule to treat men with incurable prostate cancer

NewYork-Presbyterian and Weill Cornell Medicine have begun the first clinical trial in the United States that uses a small molecule to treat men with progressive prostate cancer that has spread beyond the prostate and is no longer responding to hormonal therapy.

31 May 2017

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high-risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center

31 May 2017

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

The Radboud University Medical Center in the Netherlands, the Instituto de Medicina Molecular Lisboa in Portugal, and PATH in Seattle, Washington announced today that they will collaborate to test a new approach to malaria vaccine development in humans for the first time.

31 May 2017

Researchers develop new plasmonic sensor that improves early detection of cancer biomarkers

A new plasmonic sensor developed by researchers at the University of Illinois at Urbana-Champaign will serve as a reliable early detection of biomarkers for many forms of cancer and eventually other diseases.

31 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

New IsoPSA assay detects prostate cancer more precisely than current tests

A team of researchers from Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, Kaiser Permanente Northwest, and other clinical sites have demonstrated that a new blood test known as IsoPSA detects prostate cancer more precisely than current tests in two crucial measures - distinguishing cancer from benign conditions, and identifying patients with high-risk disease.

15 May 2017

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

ImmusanT, Inc., a clinical-stage company developing Nexvax2, a therapeutic vaccine intended to protect against the effects of gluten exposure while maintaining a gluten-free diet in HLA-DQ2.5+ patients with celiac disease, today announced the publication of positive data from two Phase 1 clinical trials of Nexvax2 in celiac disease.

12 May 2017

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

In the body, anti-cancer immunity is immobilized by stealth cancer forces. But a natural de-immobilizer has been identified-;and it has a vendetta.

12 May 2017

Study generates comprehensive catalog of diseases linked to variations in HLA genes

A study led by researchers at Vanderbilt University Medical Center and the University of Arizona College of Pharmacy has generated the first comprehensive catalog of diseases associated with variations in human leukocyte antigen genes that regulate the body's immune system.

11 May 2017

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia into complete initial remission, researchers have now opened a first-in-human clinical trial aimed at reducing the rate of relapse after the therapy, which is about 50 percent.

9 May 2017

Novel strategy may improve survival of grafts, outcomes in high-risk corneal transplant patients

Treating donor corneas with a cocktail of molecules prior to transplanting to a host may improve survival of grafts and, thus, outcomes in high-risk corneal transplant patients, according to a new study led by researchers at Massachusetts Eye and Ear.

2 May 2017

Alere introduces first-ever highly sensitive malaria test for asymptomatic infections

Alere Inc., a global leader in rapid diagnostics, today announced the launch of its Alere™ Malaria Ag P.f, a major technological breakthrough in high-sensitivity rapid testing versus currently available malaria RDTs.

27 Apr 2017

Study identifies expression of tumor antigen as marker for aggressive ovarian cancer

Patients who expressed the tumor antigen NY-ESO-1 had more aggressive cancers and were more likely to die early from their disease, according to a large study conducted by Roswell Park Cancer Institute researchers and published online ahead of print in the journal Gynecologic Oncology.

26 Apr 2017

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

Cellular therapy hasn't had much success in fighting solid tumors, partly because it's been difficult to deliver anti-cancer T cells to the tumors.

25 Apr 2017

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.

24 Apr 2017

Study highlights need for personalized approaches to prostate cancer screening in high-risk black men

A new study indicates that higher prostate cancer death rates among black men in the US may be due to a higher risk of developing preclinical prostate cancer as well as a higher risk of that cancer progressing more quickly to advanced stages.

24 Apr 2017

NIH announces 2017 ICEMR awards for 7 international malaria research centers

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, today announced approximately $9 million in first-year funding, subject to availability, for seven malaria research centers around the world.

21 Apr 2017

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays in chronic inflammatory conditions.

20 Apr 2017

Antigen News and Research

Research shows new Zika virus vaccine that offers 100% protection in mice

Researchers find new way to block type 1 diabetes

Clinical trial uses small molecule to treat men with incurable prostate cancer

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

Researchers develop new plasmonic sensor that improves early detection of cancer biomarkers

Scientists unravel mystery of T cell signaling process vital to immune response

New IsoPSA assay detects prostate cancer more precisely than current tests

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

Study generates comprehensive catalog of diseases linked to variations in HLA genes

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

Novel strategy may improve survival of grafts, outcomes in high-risk corneal transplant patients

Alere introduces first-ever highly sensitive malaria test for asymptomatic infections

Study identifies expression of tumor antigen as marker for aggressive ovarian cancer

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Study highlights need for personalized approaches to prostate cancer screening in high-risk black men

NIH announces 2017 ICEMR awards for 7 international malaria research centers

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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