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Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
New comprehensive study lists top personal health expenses in the U.S.

New comprehensive study lists top personal health expenses in the U.S.

Just 20 conditions make up more than half of all spending on health care in the United States, according to a new comprehensive financial analysis that examines spending by diseases and injuries. [More]
Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

If you're 65 or older and taking more than four medications, resolve to talk to your doctor about doing a New Year's triage to make sure too many pills aren't making you sick, advises Milta Little, D.O., associate professor of geriatrics at Saint Louis University. [More]
OTC medical device receives CE Mark approval to treat pain linked to fibromyalgia

OTC medical device receives CE Mark approval to treat pain linked to fibromyalgia

AVACEN Medical announced its AVACEN 100, Class-IIa, OTC medical device has received the CE Mark approval to treat widespread pain associated with fibromyalgia. [More]
TSRI scientists shed light on how antiviral drug stops influenza infections

TSRI scientists shed light on how antiviral drug stops influenza infections

A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus. [More]
RAGE regulates key signaling pathway that promotes acute and chronic inflammation

RAGE regulates key signaling pathway that promotes acute and chronic inflammation

Researchers have shown that Receptor for Advanced Glycation End Products helps to regulate a key signaling pathway known to promote both acute and chronic inflammation. [More]
‘Watershed in metabolon research’ unlocks plants' secret medicinal toolbox

‘Watershed in metabolon research’ unlocks plants' secret medicinal toolbox

Metabolons, near-mythical clusters of enzymes, have been discovered for the first time. Using fluorescent tags and microscopy -- molecular movie technology - scientists have confirmed their existence, thus unlocking plants' secret medicinal toolbox. [More]
TSRI scientist receives Outstanding Investigator Grant to focus on memory formation research

TSRI scientist receives Outstanding Investigator Grant to focus on memory formation research

Ron Davis, chair of the Department of Neuroscience on the Florida campus of The Scripps Research Institute has been awarded a $5 million Outstanding Investigator Grant, one of the first of its kind, by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health. [More]
U-M researchers identify gene expression linked to gender differences in autoimmune diseases

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

Women represent nearly 8 out of every 10 people with autoimmune diseases. Although the statistics are well-known, the scientific community is still trying to figure out why women's immune systems are more likely to become overactive and attack their own healthy cells. [More]
New review highlights need to reassess use of biologics for treating rheumatoid arthritis patients

New review highlights need to reassess use of biologics for treating rheumatoid arthritis patients

The use of biologics, which are generally made from human and/or animal materials, has significantly changed the management of rheumatoid arthritis over the last decade, becoming the cornerstone treatment for many patients. [More]
Researchers use worms as model system to study how gut microbiome influences disease

Researchers use worms as model system to study how gut microbiome influences disease

The billions of microorganisms living within the human digestive tract appear to play a significant role in health and disease, notably metabolic syndrome, autoimmune disorders and diabetes - but how these organisms do so is not well understood. [More]
Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers at the University of California, Riverside have camels and llamas to thank for their development of a new cancer treatment that is highly selective in blocking the action of faulty matrix metalloproteinases (MMPs). [More]
Scientists discover possible way to stop activation of proteins known to cause age-related diseases

Scientists discover possible way to stop activation of proteins known to cause age-related diseases

Researchers at the University of Surrey, in collaboration with the Universities of Reading and Cologne, and the Royal Berkshire Hospital, have discovered that it is possible to stop the activation of a group of proteins (NADPH Oxidase) known to cause most of the diseases of ageing. [More]
Common bacterium that causes gum infections may trigger rheumatoid arthritis

Common bacterium that causes gum infections may trigger rheumatoid arthritis

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory "autoimmune" response characteristic of chronic, joint-destroying rheumatoid arthritis (RA). [More]
Scientists develop first functional biological pacemaker from human stem cells

Scientists develop first functional biological pacemaker from human stem cells

Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy. [More]
Initial rheumatoid arthritis symptoms often invisible to others, survey reveals

Initial rheumatoid arthritis symptoms often invisible to others, survey reveals

Rheumatoid Arthritis is a chronic disease characterized by joint swelling, pain, and stiffness that affects approximately 1.3 million individuals in the U.S. Unlike the more common osteoarthritis, RA is an autoimmune condition in which the body's immune system mistakenly attacks healthy tissue. [More]
Researchers show how common bacterium in improperly cooked chicken triggers GBS

Researchers show how common bacterium in improperly cooked chicken triggers GBS

A Michigan State University research team is the first to show how a common bacterium found in improperly cooked chicken causes Guillain-Barre Syndrome, or GBS. [More]
Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Psoriasis is well-known for causing too many skin cells on elbows, knees, and across the body, but people living with psoriasis may also be at an increased risk of heart disease. [More]
Rheumatology and arthritis societies call for more support to improve arthritis treatment in Wales

Rheumatology and arthritis societies call for more support to improve arthritis treatment in Wales

Rheumatology and arthritis societies raise concerns for arthritis services in Wales and call for more support to improve long-term patient outcomes. [More]
Research validates effectiveness of world-first dental vaccine

Research validates effectiveness of world-first dental vaccine

A world-first vaccine developed by Melbourne scientists, which could eliminate or at least reduce the need for surgery and antibiotics for severe gum disease, has been validated by research published this weekend in a leading international journal. [More]
Research unlocks potential new therapies for inflammatory diseases

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue. [More]
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