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Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
FDA approves Novartis' Ilaris for treatment of active systemic juvenile idiopathic arthritis

FDA approves Novartis' Ilaris for treatment of active systemic juvenile idiopathic arthritis

Novartis announced today that the US Food and Drug Administration has approved Ilaris (canakinumab) for the treatment of active systemic juvenile idiopathic arthritis in patients aged 2 years and older. [More]
Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Idera Pharmaceuticals today announced presentation of data from its randomized, double-blind, placebo-controlled Phase 2 trial that showed improvements from baseline of up to 90% in Psoriasis Area Severity Index scores in patients with moderate to severe plaque psoriasis following four weeks of treatment with the Toll-like Receptor antagonist IMO-3100. [More]
POZEN announces revenue of $1.4 million for first quarter 2013

POZEN announces revenue of $1.4 million for first quarter 2013

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, today announced results for the first quarter ended March 31, 2013. [More]

Rigel reports net loss of $25.6 million in first quarter 2013

Rigel Pharmaceuticals, Inc. today reported financial results for the first quarter ended March 31, 2013. For the first quarter of 2013, Rigel reported a net loss of $25.6 million, or $0.29 per share, compared to a net loss of $23.2 million, or $0.32 per share, in the first quarter of 2012. Weighted average shares outstanding for the first quarters of 2013 and 2012 were 87.1 million and 71.4 million, respectively. [More]
Regeneron Pharmaceuticals expands ophthalmology portfolio

Regeneron Pharmaceuticals expands ophthalmology portfolio

Regeneron Pharmaceuticals, Inc. today announced that it has expanded its ophthalmology portfolio by acquiring full exclusive rights to two families of novel antibodies invented at Regeneron and previously included in Regeneron's antibody collaboration with Sanofi. [More]
EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, announced the issuance of a U.S. patent covering methods of treatment and formulations for its clinical-stage compound, 2-methoxyestradiol. [More]
New study shows that exercise does not worsen pain associated with fibromyalgia

New study shows that exercise does not worsen pain associated with fibromyalgia

For many people who have fibromyalgia, even the thought of exercising is painful. Yet a new study from Wake Forest Baptist Medical Center shows that exercise does not worsen the pain associated with the disorder and may even lessen it over time. [More]
TSRI scientists find dissimilar genes that keep very similar shapes

TSRI scientists find dissimilar genes that keep very similar shapes

Solving the structure of a critical human molecule involved in cancer, scientists at The Scripps Research Institute have found what they call a good example of structural conservation-dissimilar genes that keep very similar shapes. [More]

Rituximab joint protective benefits capped

Study findings may help guide rituximab dosing regimens for patients with rheumatoid arthritis. [More]
Scientists discover novel drug molecule that reduces swelling, inflammation in arthritic joints

Scientists discover novel drug molecule that reduces swelling, inflammation in arthritic joints

A gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis. [More]
Sufferers of gout and elevated uric acid levels have significantly increased death risks

Sufferers of gout and elevated uric acid levels have significantly increased death risks

A new study led by researchers at the Graduate Entry Medical School (GEMS), University of Limerick (UL) has found that people suffering from gout and elevated serum uric acid have significantly increased risks of death. [More]
UCSF study focuses on vexing problems of handling skin cancers among elderly patients

UCSF study focuses on vexing problems of handling skin cancers among elderly patients

Surgery is often recommended for skin cancers, but older, sicker patients can endure complications as a result and may not live long enough to benefit from the treatment. [More]

Researchers say tiny thymus teaches immune system to ignore foreign bacteria in gut

The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say. [More]
Opsona raises €33M in oversubscribed financing round

Opsona raises €33M in oversubscribed financing round

Opsona Therapeutics Limited, the innate immune drug development company, today announced that it has raised €33 million (US $ 43 million) in an oversubscribed Series C financing. [More]
Upcoming symposium to offer highlights of 150-year history of Hospital for Special Surgery

Upcoming symposium to offer highlights of 150-year history of Hospital for Special Surgery

An upcoming symposium will offer highlights of the 150-year history of Hospital for Special Surgery and at the same time provide a fascinating look at the evolution of medicine from the "Dark Ages" of the Civil War period to modern medicine as we know it today. [More]

Ampio completes patient enrollment in dose-escalation run-in study of Ampion for treatment of knee osteoarthritis

Ampio Pharmaceuticals, Inc. today announced the completion of patient enrollment in a dose-escalation run-in study to a Phase III pivotal trial evaluating Ampion in the treatment of moderate to severe osteoarthritis of the knee. [More]
Personalized knee replacement: an interview with Dr Martin, Preferred Orthopedics of the Palm Beaches

Personalized knee replacement: an interview with Dr Martin, Preferred Orthopedics of the Palm Beaches

Knee replacement surgery has traditionally been performed using off-the-shelf implants because of the limitations of technology. As with most industries, evolution does occur. [More]
MCCIR scientists use video imaging to investigate effectiveness of rituximab in killing cancerous B cells

MCCIR scientists use video imaging to investigate effectiveness of rituximab in killing cancerous B cells

Scientists from the Manchester Collaborative Centre for Inflammation Research have discovered why a particular cancer drug is so effective at killing cells. [More]
Vertex presents data of telaprevir Phase 3b CONCISE study in people with genotype 1 chronic HCV

Vertex presents data of telaprevir Phase 3b CONCISE study in people with genotype 1 chronic HCV

Vertex Pharmaceuticals Incorporated today announced new data from an interim analysis of the exploratory global Phase 3b CONCISE study evaluating the potential to shorten total treatment with telaprevir combination therapy to 12 weeks in certain people with genotype 1 chronic hepatitis C virus infection who have the IL28B CC genotype. [More]
Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Hospital for Special Surgery in New York City has received a $5.6 million grant from The Tow Foundation to establish the Hospital for Special Surgery Genomics Center. [More]