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Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
UK Biobank celebrates 10 years of pioneering health research

UK Biobank celebrates 10 years of pioneering health research

UK Biobank, a large scale medical research programme, is an extraordinary undertaking with the ultimate aim of improving the prevention, diagnosis and treatment of host of serious conditions. [More]
Depression screening tools may lead to misdiagnosis in children and adolescents

Depression screening tools may lead to misdiagnosis in children and adolescents

In Canada and the U.S., doctors are increasingly being encouraged to try to identify depression in children and adolescents - even if they do not have obvious indications of the disease. In order to do so, the physicians often use short questionnaires that ask about symptoms of depression [More]
Combination therapy shows no better benefits than placebo for patients with knee osteoarthritis

Combination therapy shows no better benefits than placebo for patients with knee osteoarthritis

Chondroitin sulfate (CS) plus glucosamine sulfate (GS) was no better than placebo for reducing pain and function impairment in a multicenter, randomized, double-blinded, placebo-controlled study of 164 patients with knee osteoarthritis. [More]
Generic biologic drugs appear to be as effective as brand-name versions

Generic biologic drugs appear to be as effective as brand-name versions

Generic forms of a biologic drug used to treat rheumatoid arthritis, inflammatory bowel disease and psoriasis appear to be as safe and effective as their brand-name counterparts, a new Johns Hopkins Bloomberg School of Public Health analysis suggests. [More]
Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Preclinical data on Selecta’s novel immune tolerance platform published in Nature Nanotechnology

Selecta Biosciences, Inc., a clinical-stage biopharmaceutical company developing targeted antigen-specific immune therapies for rare and serious diseases, announced today that Nature Nanotechnology has published an article that presents preclinical results from Selecta’s research which demonstrate the broad potential applicability of Selecta’s novel immune tolerance platform. [More]
New research opens door to influencing immune system

New research opens door to influencing immune system

A new international collaboration involving scientists at The Scripps Research Institute opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis. [More]
Dengue, chikungunya and Zika virus infections can be potential health threat to travelers

Dengue, chikungunya and Zika virus infections can be potential health threat to travelers

As the eyes of the world turn to Rio de Janiero for the 2016 Summer Olympics, the spread of the Zika virus in Brazil is a growing concern — but Zika is not the only disease that mosquitoes can spread to humans. [More]
TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

In addition to its more obvious ills, type 2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options. [More]
Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Researchers at Johns Hopkins Medicine report they have identified a biochemical pathway linking oxidative stress and the amino acid cysteine in Huntington's disease. [More]
Report: Britons at risk of long-term disability, reduced life expectancy due to delays in treatment services

Report: Britons at risk of long-term disability, reduced life expectancy due to delays in treatment services

Up to a million Britons are at risk of preventable, long-term disability and reduced life expectancy due to delays in referrals to specialist advice and treatment services, according to the most comprehensive audit of rheumatology services carried out across England and Wales. [More]
Scientist develops new method for identifying proteins to build new biologics

Scientist develops new method for identifying proteins to build new biologics

A University of Toronto scientist has developed a new method for identifying the raw ingredients necessary to build 'biologics', a powerful class of medications that has revolutionized treatment of diseases like rheumatoid arthritis and some cancers. [More]
Exercise therapy could be effective alternative for treating meniscus injuries

Exercise therapy could be effective alternative for treating meniscus injuries

Three out of four people could avoid knee surgery with a new form of exercise therapy, with significant cost savings for society [More]
Scientists receive $2.4 million grant to advance stem cell therapy for Parkinson's disease

Scientists receive $2.4 million grant to advance stem cell therapy for Parkinson's disease

Scientists at The Scripps Research Institute and Scripps Clinic have received a grant of nearly $2.4 million from the California Institute for Regenerative Medicine to support safety and quality tests of a potential stem cell therapy for Parkinson's disease. [More]
HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis

HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis

Researchers at Hospital for Special Surgery have launched a study to determine if a treatment using stem cells could help people with painful knee arthritis. [More]
Researchers identify how sensory nerve receptors work together to transmit itch signals

Researchers identify how sensory nerve receptors work together to transmit itch signals

Researchers have found how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord, where neurons then carry those signals to the brain. Their discovery may help scientists find more effective ways to make itching stop. [More]
Researchers shed light on involvement of immune system in schizophrenia

Researchers shed light on involvement of immune system in schizophrenia

Using data from the largest ever genetic study of schizophrenia, researchers have shed light on the role of the immune system. [More]
Study provides more insight into effects of DBS in treatment of Alzheimer's disease

Study provides more insight into effects of DBS in treatment of Alzheimer's disease

New findings published today by a team of researchers led by Dr. Andres Lozano at the Krembil Neuroscience Centre of Toronto Western Hospital have provided further insight into the effects of Deep Brain Stimulation (DBS) in the treatment of Alzheimer's disease. [More]
Scientists develop new way to resurface arthritic hip joint

Scientists develop new way to resurface arthritic hip joint

With a goal of treating worn, arthritic hips without extensive surgery to replace them, scientists have programmed stem cells to grow new cartilage on a 3-D template shaped like the ball of a hip joint. [More]
New report reveals prescription medication costs may increase up to 13% in 2016

New report reveals prescription medication costs may increase up to 13% in 2016

Prescription medication costs are expected to rise at least 11 percent, and possibly up to 13 percent, in 2016, according to a new report on national trends and projections in prescription drug expenditures. [More]
First arthritis model in zebrafish offers new hope for finding biological cure

First arthritis model in zebrafish offers new hope for finding biological cure

The very first bony fish on Earth was susceptible to arthritis, according to a USC-led discovery that may fast-track therapeutic research in preventing or easing the nation's most common cause of disability. [More]
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