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Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
Research reveals key role of fibroblasts in development of rheumatoid arthritis

Research reveals key role of fibroblasts in development of rheumatoid arthritis

A study led by researchers at the University of Birmingham reveals the key role of different types of fibroblast cells in the development of rheumatoid arthritis (RA), opening up a new avenue for research into treatment of the disease. [More]
TSRI scientists unravel mystery of ‘food coma’ phenomenon

TSRI scientists unravel mystery of ‘food coma’ phenomenon

Anyone who has drifted into a fuzzy-headed stupor after a large holiday meal is familiar with the condition commonly known as a "food coma." [More]
TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. [More]
Scientists reveal key details of the body's immune response to fungal infections

Scientists reveal key details of the body's immune response to fungal infections

Every year, fungal infections threaten thousands of patients -- from those with depressed immune systems to others who have had surgeries or devices such as catheters implanted. Moreover, some anti-fungal medications are beginning to lose their power. [More]
Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease. [More]
Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis (PsA) is an inflammatory condition closely related to and most often co-occurring with psoriasis. [More]
New study to explore ways of helping chronic pain patients get back to work

New study to explore ways of helping chronic pain patients get back to work

Researchers from the University of Warwick's Medical School are leading a novel study to explore ways of helping people with chronic pain back to work. [More]
TSRI study reveals how circadian clocks may influence cancer growth

TSRI study reveals how circadian clocks may influence cancer growth

A new study led by scientists at The Scripps Research Institute describes an unexpected role for proteins involved with our daily "circadian" clocks in influencing cancer growth. [More]
Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

A new study shows a link between mothers with rheumatoid arthritis and children with epilepsy. [More]
Barriers to internet use for self-care may be preventing women from managing chronic conditions

Barriers to internet use for self-care may be preventing women from managing chronic conditions

Barriers to internet use may be preventing chronically ill middle-aged and older women from being as healthy as they otherwise could be, new research from Oregon State University suggests. [More]
Smoking, excess weight may influence how rheumatoid arthritis symptoms improve with treatment

Smoking, excess weight may influence how rheumatoid arthritis symptoms improve with treatment

A study finds that smoking or being overweight makes it more difficult for patients with rheumatoid arthritis to achieve optimal control of inflammation and symptoms, despite standard of care treatment. [More]
CreakyJoints announces first patient-friendly guidelines for rheumatoid arthritis

CreakyJoints announces first patient-friendly guidelines for rheumatoid arthritis

CreakyJoints, the go-to source for more than 100,000 arthritis patients and their families world-wide who are seeking education, support, advocacy, and patient-centered research, today announced the forthcoming publication of “A Patient’s Guide to Living with Rheumatoid Arthritis.” [More]
TSRI study unravels how protein is directly responsible for sensing touch

TSRI study unravels how protein is directly responsible for sensing touch

A new study led by scientists at The Scripps Research Institute reveals that a protein first discovered at TSRI in 2010 is directly responsible for sensing touch. [More]
TSRI study suggests new approach to limit tumor growth by targeting immune system cells

TSRI study suggests new approach to limit tumor growth by targeting immune system cells

A new study led by scientists at The Scripps Research Institute suggests there may be a way to limit tumor growth by targeting immune system cells called macrophages. [More]
New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research has shown how the immune system avoids attacking its own tissues with antibodies - whilst still maintaining a strong defence against invaders. [More]
Arthritis drug increases effectiveness of antidepressants in bipolar patients

Arthritis drug increases effectiveness of antidepressants in bipolar patients

Giving severely depressed patients the arthritis drug celecoxib (Celebrex) dramatically boosted the effectiveness of their antidepressant medication, a Loyola study has found. [More]
TSRI scientists receive NIH grants for computational biology research

TSRI scientists receive NIH grants for computational biology research

Three groups at The Scripps Research Institute have been awarded grants from the National Institutes of Health to develop methods for computational modeling and to apply them to cutting-edge systems in biology and health. [More]
Physical, mental chronic conditions in middle-age linked to disability and social participation restrictions

Physical, mental chronic conditions in middle-age linked to disability and social participation restrictions

Middle-age adults living with a combination of arthritis, heart disease or diabetes, and depression are more likely to experience disability and limited involvement in society, new research from McMaster University has found. [More]
Large increase in BMI during puberty linked to increased risk of cardiovascular mortality in adult men

Large increase in BMI during puberty linked to increased risk of cardiovascular mortality in adult men

Boys with a large increase in body mass index (BMI) during puberty are at increased risk of death due to cardiovascular disease later in life. [More]
New research explains how tumors may impair ability of the liver to respond to caloric deprivation

New research explains how tumors may impair ability of the liver to respond to caloric deprivation

One of the worst cruelties of lethal cancer is the phenomenon called wasting, or in medical terms, cachexia (pronounced ka-CHEX-ia), in which a patient seems literally to diminish in bodily terms as the cancer ravages one or more internal organs. [More]
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