Asthma News and Research

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Asthma is a common inflammatory disease affecting the airways that leads to shortness of breath, coughing and wheezing. Symptoms range from mild to severe but are generally manageable with appropriate treatment.

Rigel earns $25M milestone payment from Astrazeneca for clinical development of fostamatinib

Rigel Pharmaceuticals, Inc. today announced that it has earned $25 million from AstraZeneca for the fulfillment of two major milestones in the agreement the two companies have regarding the clinical development of fostamatinib (R788), a novel oral syk inhibitor. The first milestone is for initiation of the phase 3 clinical program with fostamatinib in patients with rheumatoid arthritis (RA) that was announced by AstraZeneca earlier today.

29 Sep 2010

BAC completes feasibility study on CaptureSelect affinity ligands for Genmab

BAC BV, the leading provider of antibody-based affinity purification technology, today announced that it successfully completed a feasibility study in its collaboration with Genmab A/S (Copenhagen, Denmark), an international biotechnology company developing human antibody therapeutics for the potential treatment of cancer.

29 Sep 2010

Emergency treatment of anaphylaxis with epinephrine by trained non-medical professionals endorsed

The Epinephrine Roundtable was convened during the 25th Annual Meeting of the Wilderness Medical Society (WMS) in 2008 to explore areas of consensus and uncertainty in the field treatment of anaphylaxis. The panel endorsed the administration of epinephrine to treat anaphylaxis in the field under emergency conditions by trained non-medical professionals. Anaphylaxis, an acute allergic reaction, is sudden in onset and requires immediate treatment. The recommendations of the panel are published in the September issue of Wilderness & Environmental Health.

29 Sep 2010

Florida likely to seek waiver on medical loss ratio; Ariz. cuts back Medicaid benefits

The Hill Healthwatch: "Florida's 14-member insurance advisory board has unanimously passed a resolution to seek a waiver from the health law's medical loss ratio. An official with the Florida Office of Insurance Regulation tells The Hill that the board's vote means it's a 'done deal' that the state will formally seek some kind of waiver but the board is gathering public input through Oct. 8.

29 Sep 2010

People with pet allergies develop ragweed allergy symptoms: Research

Researchers found that people with pet allergies often develop ragweed allergy symptoms more quickly than others. But the study also suggests that once allergy season is in full swing, those symptom differences subside.

29 Sep 2010

Children with food allergies experience bullying: Study

In the first ever study to assess the social impact of food allergies in children, Mount Sinai researchers have found that approximately 35 percent of children with food allergies, who are over the age of five, were reported to have experienced bullying, teasing, or harassment as a result of their allergies.

28 Sep 2010

Study investigates link between cough and reflux events using sound recording device

Coughing episodes are closely related to gastroesophageal reflux symptoms in patients who experience chronic cough, irrespective of other diagnoses, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

28 Sep 2010

PGIC analysis indicates tapentadol ER tablets provide significant improvement in pain intensity

Phase 3 safety and efficacy data comparing tapentadol extended release (ER) tablets, an investigational pain medication, to placebo in patients with moderate to severe chronic low back pain have been published online by Expert Opinion on Pharmacotherapy. In addition, this study compared oxycodone controlled-release (CR) to placebo as an active control.

28 Sep 2010

Study: Genetic ancestry has no influence on how African-Americans with asthma respond to medication

Genetic ancestry has no discernible influence on how African American patients with asthma respond to medication, according to a Henry Ford Hospital study.

28 Sep 2010

Amira submits IND application for AM152 antagonist

Amira Pharmaceuticals, Inc. announced today that it has submitted an Investigational New Drug (IND) application to the US Food and Drug Administration (FDA) for AM152, a novel LPA1 antagonist. If accepted, the IND will enable Amira to begin Phase 1 safety studies with the compound in healthy subjects.

28 Sep 2010

MediciNova receives FDA approval to proceed with initial trial of ibudilast

MediciNova Inc, a biopharmaceutical company publicly traded on the NASDAQ Global Market and the Hercules Market of the Osaka Securities Exchange (Code Number:4875), today reported FDA's approval to proceed with an initial trial of the company's neurological drug candidate, ibudilast (MN-166/AV411), as a potential new pharmacotherapy for methamphetamine addiction.

27 Sep 2010

The Children's Hospital, Denver Health sign Affiliation Agreement to care for children of all ages

The Children's Hospital and Denver Health have signed an official Affiliation Agreement to leverage the substantial strengths of both institutions to provide outstanding programs in pediatric patient care, education, research and advocacy. Under the agreement, two of the largest pediatric health care providers in the region are able to provide improved access for patients, share best practices and more efficiently use resources.

27 Sep 2010

Study shows regadenoson is safe and effective for chronic lung disease

Patients at risk of coronary disease who have reactive airways may breathe easier thanks to new data released today at the 15th Annual Scientific Session of the American Society of Nuclear Cardiology. A new study shows that regadenoson may be safely tolerated by patients with chronic lung disease, providing an alternative to adenosine, which is known to induce brochoconstriction in some patients.

27 Sep 2010

Clinical Data announces Stedivaze agonist data at ASNC2010 meeting

Clinical Data, Inc., today presented data from Phase I studies of Stedivaze (apadenoson), which demonstrated overall safety and tolerability in patients with asthma and chronic obstructive pulmonary disease (COPD).

27 Sep 2010

Astellas Pharma announces Phase IV study results of Lexiscan injection at ASNC session

Today Astellas Pharma US, Inc. announced results of a Phase IV study showing Lexiscan(regadenoson) Injection was comparable to placebo in causing a >15% decrease in forced expiratory volume in one second (FEV1) in subjects with asthma or chronic obstructive pulmonary disease (COPD) who are likely candidates for myocardial perfusion imaging (MPI) studies.

27 Sep 2010

Dual eligible patients more likely to be hospitalized than Medicare beneficiaries: AHRQ

Americans who were eligible for coverage under both Medicare and Medicaid in 2008 were hospitalized for bed sores, asthma and diabetes at more than twice the rate of other Medicare beneficiaries, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

27 Sep 2010

Victorian health report card

Results from the 2008 Victorian Population Health Survey of more than 34,000 people are out. Broadly the picture is not too pleasing with signs of poor health like weight gain and disease. People are eating less fruit and vegetables, but smoking is down and asthma is less prevalent than it was earlier in the decade.

26 Sep 2010

Progress in realizing potential of satellite measurements of air pollution

In many developing countries, the absence of surface-based air pollution sensors makes it difficult, and in some cases impossible, to get even a rough estimate of the abundance of a subcategory of airborne particles that epidemiologists suspect contributes to millions of premature deaths each year. The problematic particles, called fine particulate matter (PM2.5), are 2.5 micrometers or less in diameter, about a tenth the fraction of human hair. These small particles can get past the body's normal defenses and penetrate deep into the lungs.

24 Sep 2010

Comic books to educate young men about testicular cancer

Comic books may help to educate young men and their partners about testicular cancer and its early symptoms and encourage them to do more self-screening, according to Ryerson University School of Fashion professor and comic book artist David Brame.

24 Sep 2010

Technologic innovation — Telephones! — could save health system money

Health-coaching more patients over the phone could help save the system money according to a study published Wednesday in the New England Journal of Medicine and noticed by the Wall Street Journal's Health Blog. "Typically this kind of care management, as it's called, is offered to people who have trouble managing their chronic conditions or who are facing a big treatment decision — such as surgery or medical management for lower back pain.

24 Sep 2010

Asthma News and Research

Further Reading

Rigel earns $25M milestone payment from Astrazeneca for clinical development of fostamatinib

BAC completes feasibility study on CaptureSelect affinity ligands for Genmab

Emergency treatment of anaphylaxis with epinephrine by trained non-medical professionals endorsed

Florida likely to seek waiver on medical loss ratio; Ariz. cuts back Medicaid benefits

People with pet allergies develop ragweed allergy symptoms: Research

Children with food allergies experience bullying: Study

Study investigates link between cough and reflux events using sound recording device

PGIC analysis indicates tapentadol ER tablets provide significant improvement in pain intensity

Study: Genetic ancestry has no influence on how African-Americans with asthma respond to medication

Amira submits IND application for AM152 antagonist

MediciNova receives FDA approval to proceed with initial trial of ibudilast

The Children's Hospital, Denver Health sign Affiliation Agreement to care for children of all ages

Study shows regadenoson is safe and effective for chronic lung disease

Clinical Data announces Stedivaze agonist data at ASNC2010 meeting

Astellas Pharma announces Phase IV study results of Lexiscan injection at ASNC session

Dual eligible patients more likely to be hospitalized than Medicare beneficiaries: AHRQ

Victorian health report card

Progress in realizing potential of satellite measurements of air pollution

Comic books to educate young men about testicular cancer

Technologic innovation — Telephones! — could save health system money

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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