Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.

17 Aug 2023

Can nutritional interventions positively impact psoriasis severity?

Improvement in psoriasis (Ps) through nutritional strategies.

15 Aug 2023

Novel antibody could be safer and more effective than existing treatments for autoimmune diseases

Researchers have shown that a novel antibody generated to target an 'essential amino acid sequence' of both interleukin-17A and F has greater activity and potentially fewer side effects than existing biological therapies for conditions such as as rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD).

14 Aug 2023

Adenovirus infection linked to rare blood clotting disorder

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia.

10 Aug 2023

Researchers discover possible new biomarker of MS-like autoimmune disease

It has been known for several years that the diagnosis "multiple sclerosis" conceals a whole range of different illnesses, each requiring customized treatment. Researchers at the University of Basel and the University Hospital of Basel have now described a possible new MS-like disease and explained how to diagnose it.

8 Aug 2023

EULAR releases new recommendations for non-pharmacological management of SLE and SSc

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem involvement. Systemic sclerosis (SSc) or scleroderma is another rheumatic autoimmune disease that affects blood vessels, skin, and visceral organs.

7 Aug 2023

Thymus gland critical for adult health, study finds

The thymus gland-; which produces immune T cells before birth and during childhood-; is often regarded as nonfunctional in adults, and it's sometimes removed during cardiac surgery for easier access to the heart and major blood vessels.

2 Aug 2023

Childhood trauma can lead to physical and cognitive impairments in old age

Adverse childhood experiences have impacts deep into old age, especially for those who experienced violence, and include both physical and cognitive impairments.

2 Aug 2023

Study offers deeper understanding of regulatory T cells yielding therapeutic benefits

Decades of research have left knowledge gaps about cells that regulate the immune system: Purdue and NIH.

1 Aug 2023

The roles and plausible mechanisms of pyroptosis in renal inflammation and fibrosis

Researchers summarize available data on pyroptosis in the context of renal fibrosis, as well as its prevention and treatment.

1 Aug 2023

Experts call for urgent mental health support for autoimmune disease patients

More than half of patients with auto-immune conditions experience mental health conditions such as depression or anxiety, yet the majority are rarely or never asked in clinic about mental health symptoms, according to new research from the University of Cambridge and King's College London.

26 Jul 2023

The association of dietary patterns with Alzheimer’s disease and related dementia symptomology

A new paper discusses the impact of diet on the risk of AD, in which researchers describe the interrelationship between specific nutrients, dietary patterns, other risk factors for AD, and psychosocial factors driving these patterns.

24 Jul 2023

T cells can be used to identify type 1 diabetes risk, study shows

Scripps Research scientists have shown that analyzing a certain type of immune cell in the blood can help identify people at risk of developing type 1 diabetes, a life-threatening autoimmune disease.

19 Jul 2023

m6A modification as a potential therapeutic target for autoimmune diseases

N6-methyladenosine (m6A) is the most extensive studied RNA modification across various species, and the important effect of m6A modification in immune system has been revealed in distinct contexts, including mRNA metabolism, cell differentiation, proliferation and response to stimulation.

14 Jul 2023