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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.
NC State researchers develop technique that allows ultrasound to penetrate bone or metal

NC State researchers develop technique that allows ultrasound to penetrate bone or metal

Researchers from North Carolina State University have developed a technique that allows ultrasound to penetrate bone or metal, using customized structures that offset the distortion usually caused by these so-called "aberrating layers." [More]
Research paves way for improving efficacy of ALS treatement

Research paves way for improving efficacy of ALS treatement

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that primarily kills motor neurons, leading to paralysis and death 2 to 5 years from diagnosis. Currently ALS has no cure. Despite promising early-stage research, the majority of drugs in development for ALS have failed. Now researchers have uncovered a possible explanation. [More]
Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

In a new study conducted by the Sagol Department of Neurobiology at the University of Haifa and published recently in the Journal of Neuroscience, researchers report that they've found a way to improve memory by manipulating a specific molecule that is known to function poorly in old age and is closely linked to Alzheimer's disease. [More]
Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

New evidence that immune checkpoint inhibitors may work in glioblastoma and brain metastases was presented today by Dr Anna Sophie Berghoff at the ESMO Symposium on Immuno-Oncology 2014 in Geneva, Switzerland. [More]
AGA's journals highlight important updates into treatments for cirrhosis, NAFLD

AGA's journals highlight important updates into treatments for cirrhosis, NAFLD

Cirrhosis and nonalcoholic fatty liver disease (NAFLD) are two serious liver conditions with limited pharmacological treatments. The December issues of AGA's journals -- Clinical Gastroenterology and Hepatology and Gastroenterology -- highlight important updates into treatments for these two debilitating diseases. [More]
BIDMC's George Tsokos receives two prestigious awards at 2014 ACR Annual Scientific Meeting

BIDMC's George Tsokos receives two prestigious awards at 2014 ACR Annual Scientific Meeting

George Tsokos, MD, Chief of Rheumatology at Beth Israel Deaconess Medical Center and a national leader in the field of lupus research was honored by both the Lupus Foundation of America and the American College of Rheumatology with two prestigious awards presented during the 2014 ACR Annual Scientific Meeting recently held in Boston. [More]
Researchers examine genomic landscapes of humans and mice

Researchers examine genomic landscapes of humans and mice

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such as the immune system, metabolism and stress response - are so different from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes. [More]
MD Anderson study sheds light on little-known protein complex

MD Anderson study sheds light on little-known protein complex

A study at The University of Texas MD Anderson Cancer Center led by Mong-Hong Lee, Ph.D., a professor of molecular and cellular oncology, has demonstrated the significance of CSN6 in regulating Myc which may very well open up a new pathway for treating and killing tumors. [More]
MGH investigators develop system to accurately track the process of falling asleep

MGH investigators develop system to accurately track the process of falling asleep

Massachusetts General Hospital investigators have developed a system to accurately track the dynamic process of falling asleep, something has not been possible with existing techniques. In their report in the October issue of the open-access journal PLOS Computational Biology, the research team describes how combining key physiologic measurements with a behavioral task that does not interfere with sleep onset gives a better picture of the gradual process of falling asleep. [More]
New treatment for Marfan syndrome works as well as beta blockers

New treatment for Marfan syndrome works as well as beta blockers

A new treatment for Marfan syndrome, a rare genetic disease that can lead to heart problems, works as well as the currently recommended medical therapy, beta blockers, according to an article in the New England Journal of Medicine. [More]
Snus consumption in Norway is highest among young people

Snus consumption in Norway is highest among young people

The increase in Scandinavian snus consumption in Norway is highest among young people, according to a new report from the Norwegian Institute of Public Health. [More]
SRY protein alters specific gender-related tissue in males before birth

SRY protein alters specific gender-related tissue in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges. [More]
Special receptor signalling mediates astrocytic hyperactivity in  Alzheimer's disease mouse model

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions. [More]
People who handle complex jobs may have longer-lasting memory and thinking abilities

People who handle complex jobs may have longer-lasting memory and thinking abilities

People whose jobs require more complex work with other people, such as social workers and lawyers, or with data, like architects or graphic designers, may end up having longer-lasting memory and thinking abilities compared to people who do less complex work, according to research published in the November 19, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Gene therapy transforms life for men with severe form of hemophilia B

Gene therapy transforms life for men with severe form of hemophilia B

Gene therapy developed at St. Jude Children's Research Hospital, University College London and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting protein Factor IX that has allowed some to adopt a more active lifestyle, researchers reported. [More]
Leaders in research hope to uncover promising drugs in pharma libraries, conduct clinical trials

Leaders in research hope to uncover promising drugs in pharma libraries, conduct clinical trials

Drugs for brain diseases such as Alzheimer's, Parkinson's, and motor neurone disease that have stalled in development could be revived thanks to the efforts of a global coalition of non-profit organizations and funders announced today. [More]
Blocking key brain receptor cell could neutralize biological consequences of Alzheimer's

Blocking key brain receptor cell could neutralize biological consequences of Alzheimer's

Blocking a key receptor in brain cells that is used by oxygen free radicals could play a major role in neutralizing the biological consequences of Alzheimer's disease, according to researchers at Temple University. [More]
Stanford scientists explore how out-of-sync circadian clock impairs brain function

Stanford scientists explore how out-of-sync circadian clock impairs brain function

Anyone who has struggled with a foggy brain while adjusting to daylight saving time knows first-hand how an out-of-sync circadian clock can impair brain function. [More]
Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen Research & Development, LLC today announced the submission of a New Drug Application (NDA) for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration. The NDA seeks approval for the medication as a treatment for schizophrenia in adults. [More]
New nanoparticles can simultaneously perform MRI and fluorescent imaging in living animals

New nanoparticles can simultaneously perform MRI and fluorescent imaging in living animals

MIT chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals. Such particles could help scientists to track specific molecules produced in the body, monitor a tumor's environment, or determine whether drugs have successfully reached their targets. [More]