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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.
Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

A new study from ├Ârebro University, published in Science Signaling today, shows that heart medication reduces the build-up of plaque in the brain's blood vessels in mice. The question is if this is true also in humans? If the answer is yes, it might bring scientists a step closer to developing a medicine against Alzheimer's disease. [More]
Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Researchers studying babies with a Zika virus-related birth defect say they have found previously unreported eye problems possibly linked to the virus that could result in severe visual impairment. [More]
PET imaging with PiB may help in early diagnosis of Alzheimer's disease

PET imaging with PiB may help in early diagnosis of Alzheimer's disease

The effort to find ways to detect and diagnose preclinical Alzheimer's disease (AD) has taken a big step forward with the use of positron emission tomography (PET), a "nuclear medicine" for imaging processes in the body, when PET is used with a special 'tracer' that binds to the amyloid plaques in the brain that are a characteristic cause of AD. [More]
Technical advances in neuroimaging offer new promise to clinicians

Technical advances in neuroimaging offer new promise to clinicians

The current special issue of Technology and Innovation, Journal of the National Academy of Inventors, Volume 18, Number 1 (all open access), is devoted to the evolution of neuroimaging technology, with seven articles chronicling the latest advances in this critical area. [More]
Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline. [More]
Neuroscientist distinguishes different forms of dementia using MRI scans

Neuroscientist distinguishes different forms of dementia using MRI scans

Neuroscientist Anne Hafkemeijer is able to distinguish two different forms of dementia using advanced imaging techniques. This is the first step towards early recognition of dementia in patients on the basis of brain networks. PhD defence 26 May. [More]
Alcohol exposure during early to mid-adolescence linked to chronic stress vulnerability

Alcohol exposure during early to mid-adolescence linked to chronic stress vulnerability

Drinking during early to mid-adolescence can lead to vulnerability to chronic stress, according to new research from Binghamton University, State University of New York. [More]
New computational model simulates how neurons in visual cortex process sensory stimuli

New computational model simulates how neurons in visual cortex process sensory stimuli

At any given moment, the neuronal circuits in the brain receive and process sensory information that permits us to perceive and interact with the environment. Yet it remains unclear how the visual brain processes natural stimuli. [More]
Miniature microscope helps neuroscientists identify how the brain links different memories over time

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Using a miniature microscope that opens a window into the brain, UCLA neuroscientists have identified in mice how the brain links different memories over time. While aging weakens these connections, the team devised a way for the middle-aged brain to reconnect separate memories. [More]
Study highlights disparities in care for disadvantaged children with traumatic brain injuries

Study highlights disparities in care for disadvantaged children with traumatic brain injuries

Children who suffer traumatic brain injuries can face a difficult road to recovery, requiring services such as physical therapy and mental health treatment for months or years to get their young lives back on track. [More]
Heart failure patients who receive influenza vaccine less likely to develop dementia

Heart failure patients who receive influenza vaccine less likely to develop dementia

Influenza vaccination is associated with a lower risk of dementia in patients with heart failure, according to a study in more than 20 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Ju-Chi Liu, director of the Division of Cardiovascular Medicine, Department of Medicine, Taipei Medical University - Shuang Ho Hospital, in New Taipei City, Taiwan. [More]
Cost-effectiveness tool can help guide decisions regarding proposed funds to combat Zika virus outbreak

Cost-effectiveness tool can help guide decisions regarding proposed funds to combat Zika virus outbreak

A study published in PLOS Neglected Tropical Diseases presents a cost-effectiveness tool that can help guide decisions regarding resource allocation to fund interventions targeted at curtailing the ongoing Zika virus outbreak. [More]
JBCPP journal publishes new evidence for clinical efficacy of cannabis therapy

JBCPP journal publishes new evidence for clinical efficacy of cannabis therapy

New evidence for the clinical efficacy of cannabis therapy is presented in the latest issue of the Journal of Basic and Clinical Physiology and Pharmacology, a De Gruyter publication. [More]
Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Two new studies raise enough questions about a possible link between childhood cancer and light therapy for newborn jaundice that clinicians should exercise caution in prescribing the treatment for infants whose jaundice is likely to resolve on its own, a pediatric oncologist from Dana-Farber/Boston Children's Cancer and Blood Disorders Center argues in an editorial published today by the journal Pediatrics. [More]
Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial. [More]
Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny, designer packages. [More]
Nine creative ways to improve cognitive development of children in developing countries

Nine creative ways to improve cognitive development of children in developing countries

Grand Challenges Canada, funded by the Government of Canada, and the "Saving Brains" partners today announced investments in nine creative ways to protect and nurture the cognitive development of children in developing countries. [More]
New study may contribute to ongoing debate on fortification program

New study may contribute to ongoing debate on fortification program

Fortifying the U.S. food supply with folic acid was not associated with a decline in certain birth defects that researchers expected to see in California, according to a new study from the Stanford University School of Medicine. [More]
Scientists take key step towards understanding link between obesity and physically distant diseases

Scientists take key step towards understanding link between obesity and physically distant diseases

Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis. [More]
ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

Researchers at St. Jude Children's Research Hospital have uncovered how two enzymes, ULK1 and ULK2, which are best known for their role in the degradation and recycling of proteins, control the trafficking of specific proteins. [More]
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