Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Moderate exercise may benefit patients with hypertrophic cardiomyopathy

As one of the most common causes of sudden cardiac death in young people, a diagnosis of hypertrophic cardiomyopathy can push patients into sedentary lifestyles.

17 Mar 2017

Study shows how immune cells drive heart damage in mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice.

16 Mar 2017

Researchers identify new gene that can lead to sudden death among young people

Researchers from Canada, South Africa and Italy have identified a new gene that can lead to sudden death among young people and athletes.

10 Mar 2017

Study shows that peripartum cardiomyopathy is not disease of the poor and occurs globally

Peripartum cardiomyopathy (PPCM) occurs globally and is not a disease of the poor, according to research published today in the European Journal of Heart Failure. Cases were reported from many countries for the first time.

8 Mar 2017

Scientists create organ-on-a-chip that can mimic heart's biomechanical properties

The human heart beats more than 2.5 billion times in an average lifetime. Now scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart's amazing biomechanical properties.

23 Feb 2017

Johns Hopkins researchers create mature cardiomyocytes in the laboratory from stem cells

Generating mature and viable heart muscle cells from human or other animal stem cells has proven difficult for biologists.

26 Jan 2017

Technical heart surgery procedure to be demonstrated at Arab Health 2017

A technically demanding cardiac surgery which provides hope to regional sufferers of Hypertrophic Cardiomyopathy, a common inherited cardiac condition, will be demonstrated on the UK Pavilion at Arab Health 2017.

19 Jan 2017

Researchers find striking differences between countries, age groups in access to proper care for DMD

Duchenne muscular dystrophy (DMD), a progressive muscle disease affecting one in 3800-6300 live male births and leads to ambulatory loss, respiratory problems, cardiomyopathy, and early death of patients in their 20s or 30s.

4 Jan 2017

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks.

1 Dec 2016

Research shows how machine-learning models can interpret echocardiographic images and enable HCM diagnosis

Computer algorithms can automatically interpret echocardiographic images and distinguish between pathological hypertrophic cardiomyopathy and physiological changes in athletes' hearts, according to research from the Icahn School of Medicine at Mount Sinai, published online yesterday in the Journal of the American College of Cardiology.

24 Nov 2016

Titin gene mutations affect heart function in healthy individuals, study finds

A multinational study by researchers from the UK, Singapore and Germany has discovered that gene mutations in a protein called titin affect heart function in healthy individuals.

22 Nov 2016

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle.

17 Nov 2016

Study assesses impact of diabetes mellitus on cardiac geometry

A study of U.S. Hispanics with diabetes mellitus showed a link between impaired glucose regulation and adverse measures of cardiac function and structure.

21 Oct 2016

Researchers use Thai water bug to find clues for heart muscle diseases

What can a Thai water bug teach us about our muscles, especially the heart? A lot, says Professor of Biological Science Kenneth Taylor. New research by Taylor published today in Science Advances gives scientists better insight into how the heart muscle works and how sometimes it fails.

30 Sep 2016

First-ever 'Cast & Blast' event to support research into deadly congenital heart condition

Patients, physicians and attendees will throw their lines in for an important catch today at the Caledon Mountain Trout Club during the first 'Cast & Blast' event to support research into the often fatal heart disorder called arrythmogenic right ventricular cardiomyopathy (ARVC).

15 Sep 2016

Heart specialists to examine benefit of ECG screening for student athletes

UT Southwestern Medical Center heart specialists will study whether electrocardiograms (ECGs) are useful in identifying Texas high school student athletes who are at risk of suffering sudden cardiac death.

7 Sep 2016

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Scientists at Neurimmune today described results from the Phase 1b PRIME clinical trial of the monoclonal antibody aducanumab.

1 Sep 2016

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Using advanced stem cell technology, scientists from the Icahn School of Medicine at Mount Sinai have created a model of a heart condition called hypertrophic cardiomyopathy (HCM) — an excessive thickening of the heart that is associated with a number of rare and common illnesses, some of which have a strong genetic component.

31 Aug 2016

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial.

29 Aug 2016

Sudden cardiac death in patients with HCM rarely linked to sport activity

Sudden death in patients with hypertrophic cardiomyopathy (HCM) is rarely associated with exercise, according to research presented at ESC Congress 2016 today by Dr Gherardo Finocchiaro, a cardiologist at St George's University of London, UK.

28 Aug 2016