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Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

Candida albicans is a common fungus found living in, and on, many parts of the human body. Usually this species causes no harm to humans unless it can breach the body's immune defences, where can lead to serious illness or death.

3 Sep 2013

New joint program could improve patient care, physician and staff morale

The common refrain about health care is that it's a broken system. A new joint program between the University of California, Los Angeles and the University of Southern California, demonstrates a way to mend the system with a new patient-centered program that is getting raves from patients, as well as the residents and nurses who provide their care. Results from the program are highlighted in a study being released in September.

3 Sep 2013

Transport protein actively extrudes chemicals from embryo of zebrafish

Fish possess a number of different mechanisms for protection against harmful substances in an aquatic environment. These include, for example, molecular transport systems, such as the so called ABC (ATP binding cassette) transporters, which prevent the penetration of toxic substances into cells. ABC transporters have been well investigated for mammals.

3 Sep 2013

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

This rare genetic condition can theoretically affect patients at any age but symptoms are more often observed in childhood and even uncommonly during the first days of life.

2 Sep 2013

ddPCR technology can be used to reproducibly quantify microRNA in plasma

A study published online in Nature Methods today demonstrated that Droplet Digital PCR (ddPCR-) technology can be used to precisely and reproducibly quantify microRNA (miRNA) in plasma and serum across different days, paving the way for further development of miRNA and other nucleic acids as circulating biomarkers.

2 Sep 2013

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

A drug proven effective for treatment of adults and children with sickle cell anemia reduced hospitalizations and cut annual estimated medical costs by 21 percent for affected infants and toddlers, according to an analysis led by St. Jude Children's Research Hospital. The report appears today in the advance online edition of the journal Pediatrics.

2 Sep 2013

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

A new study by researchers at the Stanford University School of Medicine could help pinpoint ways to counter the effects of the antibiotics-driven depletion of friendly, gut-dwelling bacteria.

2 Sep 2013

Holistic approach to understand and treat TB

For years, physicians around the world have watched as strain after strain of the deadly bacteria Mycobacterium tuberculosis evolves resistance to drugs.

2 Sep 2013

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Nanoscale "cages" made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study.

2 Sep 2013

Findings could alter ways in which doctors use platelets to treat traumatic injuries

A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections.

2 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

University of Notre Dame researchers, as part of a collaborative effort, have identified a protein that potentially could be a target for drugs that would help people recover faster from jet lag and better adjust their circadian rhythms during rotational shift work.

31 Aug 2013

Study describes lack of positive effects in drugs, long-term data and robust direct comparisons in RA

The German Institute for Quality and Efficiency in Health Care (IQWiG) examined 9 biotechnologically produced drugs for the treatment of adults with rheumatoid arthritis in whom prior pharmacological treatment had failed.

31 Aug 2013

Researchers develop model that completes bridge between cellular and human studies of schizophrenia

Schizophrenia is one of the most devastating neurological conditions, with only 30 percent of sufferers ever experiencing full recovery. While current medications can control most psychotic symptoms, their side effects can leave individuals so severely impaired that the disease ranks among the top ten causes of disability in developed countries.

31 Aug 2013

Researchers study reproductive stage that remains most mysterious

Mississippi State University scientists are working to find out why some pregnancies are successful and others are not.

31 Aug 2013

New angle for developing drugs to prevent thrombosis and heart attack

Platelets, which allow blood to clot, are at the heart of numerous cardiovascular problems, including heart attacks and stroke. New research has uncovered a key platelet protein that could offer a new angle for developing drugs to prevent thrombosis, or dangerous blood clots, in patients who are at high risk such as those with atherosclerosis or a history of heart problems.

31 Aug 2013

Research findings could lead to new therapeutic approaches for liver cancer

Liver cancer (Hepatocellular Carcinoma, HCC) usually arises as the result of a chronic, inflammatory liver disease. The most common causes here are excessive alcohol consumption as well as a high-fat diet and also chronic infection with the hepatitis viruses B and C. In the course of the inflammatory process, the liver cells (hepatocytes) die more frequently due to programmed cell death.

30 Aug 2013

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

St. Jude Children's Research Hospital scientists have identified a protein that certain high-risk acute lymphoblastic leukemia (ALL) cells need to survive and have used that knowledge to fashion a more effective method of killing tumor cells. The findings appear in the August 29 edition of the journal Blood.

30 Aug 2013

Glucose monitoring systems detect RBC and other interferents in burn patients blood

Glucose monitoring systems with an autocorrect feature that can detect red blood cells (hematocrit), vitamin C and other common interferents in burn patients' blood are better for monitoring care, a pilot study conducted by UC Davis researchers at the School of Medicine and College of Engineering has found.

30 Aug 2013

Findings establish gene as critical regulator of lung cancer tumor growth

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a well-known cancer-causing gene implicated in a number of malignancies plays a far more critical role in non-small cell lung cancer, the most common form of the disease, than previously thought.

30 Aug 2013

Cell News and Research

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

New joint program could improve patient care, physician and staff morale

Transport protein actively extrudes chemicals from embryo of zebrafish

Argininosuccinic aciduria (ASA) and gene therapy: an interview with Dr Julien Baruteau, UCL Institute for Women's Health, London

ddPCR technology can be used to reproducibly quantify microRNA in plasma

Drug for children with sickle cell anemia reduces hospitalizations and treatment costs

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

Holistic approach to understand and treat TB

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Findings could alter ways in which doctors use platelets to treat traumatic injuries

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

Study describes lack of positive effects in drugs, long-term data and robust direct comparisons in RA

Researchers develop model that completes bridge between cellular and human studies of schizophrenia

Researchers study reproductive stage that remains most mysterious

New angle for developing drugs to prevent thrombosis and heart attack

Research findings could lead to new therapeutic approaches for liver cancer

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

Glucose monitoring systems detect RBC and other interferents in burn patients blood

Findings establish gene as critical regulator of lung cancer tumor growth

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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