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Forced elongation of telomeres promotes differentiation of cancer cells

Researchers from the Japanese Foundation for Cancer Research in Tokyo have discovered that forced elongation of telomeres (extensions on the end of chromosomes) promotes the differentiation of cancer cells, probably reducing malignancy, which is strongly associated with a loss of cell differentiation.

28 Jun 2013

Physician offers helpful tips to a healthy summer

Summer is officially here, and for many, so is the threat of sunburn, bug bites and allergies. Deepti Shivakumar, MD, family practice at Gottlieb Memorial Hospital, offers some helpful tips to a healthy summer.

27 Jun 2013

Mouse models demonstrate new potential target in fight against Alzheimer's disease

Building on research published eight years ago in the journal Chemistry and Biology, Kenneth S. Kosik, Harriman Professor in Neuroscience and co-director of the Neuroscience Research Institute (NRI) at UC Santa Barbara, and his team have now applied their findings to two distinct, well-known mouse models, demonstrating a new potential target in the fight against Alzheimer's and other neurodegenerative diseases.

27 Jun 2013

Ingestion of nanoparticles at typical environmental levels unlikely to cause overt toxicity

Ingestion of commonly encountered nanoparticles at typical environmental levels is unlikely to cause overt toxicity, according to US researchers. Nevertheless there is insufficient evidence to determine whether chronic exposures could lead to subtle alterations in intestinal immune function, protein profiles, or microbial balance.

27 Jun 2013

Autism Speaks funds high priority research for treatment of ASD

Autism Speaks, the world's leading autism science and advocacy organization, today announced awards totaling $685,968 funding new research in areas of high priority that will advance understanding and treatment of autism spectrum disorders (ASD).

27 Jun 2013

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Two UC Irvine research groups have received $2.27 million from the JDRF to develop innovative methods of treating and possibly curing Type 1 diabetes.

27 Jun 2013

New study explains how the brain maintains zinc balance during embryonic development

A new study helps explain how parts of the brain maintain their delicate balance of zinc, an element required in minute but crucial doses, particularly during embryonic development.

27 Jun 2013

Second Edition of Human Evolutionary Genetics now available

Garland Science is proud to announce the publication of the long-awaited Second Edition of Human Evolutionary Genetics by Jobling, Hollux, Hurles, Kivisild, and Tyler-Smith.

27 Jun 2013

University of Sheffield researchers show how human skin constantly regrows

We constantly grow new skin and slough off the old. Until now, scientists have never agreed on exactly how this works, but new research from the University of Sheffield may provide the answer.

27 Jun 2013

Scientists make important step forward to find cure for cancer

Scientists at the University of East Anglia have made a major advancement in understanding tissue development that has important implications for cancer.

27 Jun 2013

Ambit Biosciences presents data from Phase 2 ACE study of quizartinib for treatment of AML

Ambit Biosciences Corporation announced today data from the Phase 2 ACE study of quizartinib (AC220), a FLT3 inhibitor, were featured in multiple presentations at the 18th Congress of the European Hematology Association in Stockholm, Sweden.

27 Jun 2013

Low-molecular-weight PAHs promote conditions for cancer growth

Tobacco smoke, diesel exhaust and oil combustion carry polycyclic aromatic hydrocarbons - PAHs that are known to cause cancer. But of these PAHs, the obviously dangerous high-molecular-weight PAHs like benzo[a]pyrene (BaP) have received the vast majority of research attention.

26 Jun 2013

Kiadis Pharma to receive innovation credit from AgentschapNL to conduct Phase II study for ATIR

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, announced today that it will receive an innovation credit of up to €3 million from AgentschapNL, a division of the Dutch Ministry of Economic Affairs, to support the Phase II clinical development of Kiadis Pharma's lead pipeline product, ATIR™

26 Jun 2013

Researchers say hCNT1 protein may affect cancer cells physiology, apart from transport function

The protein hCNT1, which plays a major role in nucleoside transport, may have other biological functions that may affect cancer cells physiology, apart from their transport function. This is the main conclusion of the new scientific work published on the journal Cell Death and Disease.

26 Jun 2013

Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma that can benefit by the treatment of ALK-inhibitors.

26 Jun 2013

Pretreatment PET staging of LS-SCLC associated with improved survival

Each year, 13 percent of all newly diagnosed lung cancer patients are diagnosed with small-cell lung cancer (SCLC). Approximately 39 percent of patients with SCLC are diagnosed with limited-stage disease, meaning the cancer is only present in one lung, but may have spread to lymph nodes or tissue between the lungs.

26 Jun 2013

Spontaneously emerging brain activity patterns preserve traces of previous cognitive activity

What if experts could dig into the brain, like archaeologists, and uncover the history of past experiences? This ability might reveal what makes each of us a unique individual, and it could enable the objective diagnosis of a wide range of neuropsychological diseases.

26 Jun 2013

Hunger not only modifies behaviour, but also changes pathways in brain

Hungry people are often difficult to deal with. A good meal can affect more than our mood, it can also influence our willingness to take risks. This phenomenon is also apparent across a very diverse range of species in the animal kingdom.

26 Jun 2013

Eisai submits BELVIQ NDS with Health Canada

Arena Pharmaceuticals, Inc. announced today that Eisai Limited (based in Mississauga, Ontario), a subsidiary of Eisai Inc., has submitted a New Drug Submission for BELVIQ (lorcaserin HCl) with Health Canada.

26 Jun 2013

Verastem announces initiation of VS-4718 Phase 1 trial in patients with advanced cancer

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced the initiation of a Phase 1 trial of VS-4718, a novel, small molecule inhibitor of focal adhesion kinase, in patients with advanced cancer.

26 Jun 2013

Cell News and Research

Forced elongation of telomeres promotes differentiation of cancer cells

Physician offers helpful tips to a healthy summer

Mouse models demonstrate new potential target in fight against Alzheimer's disease

Ingestion of nanoparticles at typical environmental levels unlikely to cause overt toxicity

Autism Speaks funds high priority research for treatment of ASD

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

New study explains how the brain maintains zinc balance during embryonic development

Second Edition of Human Evolutionary Genetics now available

University of Sheffield researchers show how human skin constantly regrows

Scientists make important step forward to find cure for cancer

Ambit Biosciences presents data from Phase 2 ACE study of quizartinib for treatment of AML

Low-molecular-weight PAHs promote conditions for cancer growth

Kiadis Pharma to receive innovation credit from AgentschapNL to conduct Phase II study for ATIR

Researchers say hCNT1 protein may affect cancer cells physiology, apart from transport function

Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

Pretreatment PET staging of LS-SCLC associated with improved survival

Spontaneously emerging brain activity patterns preserve traces of previous cognitive activity

Hunger not only modifies behaviour, but also changes pathways in brain

Eisai submits BELVIQ NDS with Health Canada

Verastem announces initiation of VS-4718 Phase 1 trial in patients with advanced cancer

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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