Chemotherapy News and Research RSS Feed - Chemotherapy News and Research

Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.
New NCCN Imaging AUC released for eight new cancers

New NCCN Imaging AUC released for eight new cancers

The National Comprehensive Cancer Network, a Centers for Medicare & Medicaid Services-approved provider-led entity for imaging appropriate use criteria, continues to build its library of AUC and has published NCCN Imaging Appropriate Use Criteria for eight new cancer types. Launched in June 2016, NCCN Imaging AUC currently are available for 20 cancer types. [More]
Outpatient CLABSIs costly for pediatric stem cell transplant and oncology patient population

Outpatient CLABSIs costly for pediatric stem cell transplant and oncology patient population

Pediatric stem cell transplant and cancer patients often are discharged from the hospital with an external central venous line for medications that parents or other caregivers must clean and flush daily to avoid potentially life-threatening infections. [More]
NEJM publishes MINDACT trial results

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy. [More]
Sanford-NDSU Collaborative Seed Grant Program provides funding for three health research projects

Sanford-NDSU Collaborative Seed Grant Program provides funding for three health research projects

Three research projects have received $250,000 in seed funding from the Sanford Health NDSU Collaborative Seed Grant program. NDSU researchers will have opportunities to collaborate with investigators from Sanford Research. [More]
ESC releases novel position paper on tackling cardiotoxicity of anticancer treatments

ESC releases novel position paper on tackling cardiotoxicity of anticancer treatments

The European Society of Cardiology has launched a novel position paper, under the auspices of its Committee for Practice Guidelines, on tackling the cardiac toxicity of anticancer therapies. The cardio-oncology paper is published online today in European Heart Journal and on the ESC Website. [More]
New drug delivery system slows and controls tumors not aiming for complete elimination

New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination. [More]
Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. [More]
Breakthrough in cancer cell screening advances personalised treatment of childhood leukaemia

Breakthrough in cancer cell screening advances personalised treatment of childhood leukaemia

Researchers at Newcastle University have been able to accurately predict how children whose cancer returns after treatment for leukaemia are likely to respond to further treatment. [More]
Genetic test may be able to predict need for chemotherapy in early-stage breast cancer

Genetic test may be able to predict need for chemotherapy in early-stage breast cancer

Patients with early stage breast cancer who have a low genetic risk of disease recurrence may not need to have chemotherapy, report researchers. [More]
Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors

Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors

A Kids' Brain Tumor Cure Foundation, Solving Kids' Cancer and the Ty Louis Campbell Foundation announce their joint financial support of a Phase 1 clinical trial to test the safety and efficacy of combination checkpoint inhibitors in the treatment of children with brain tumors. [More]
NIBIB researchers develop nanovaccine to enhance cancer immunotherapy

NIBIB researchers develop nanovaccine to enhance cancer immunotherapy

NIBIB researchers have created a nanovaccine that could make a current approach to cancer immunotherapy more effective while also reducing side effects. [More]
Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals). [More]
Checkpoint inhibitor for treatment of NSCLC patients shows indication of added benefit

Checkpoint inhibitor for treatment of NSCLC patients shows indication of added benefit

Nivolumab has been approved since April 2016 as a checkpoint inhibitor for the treatment of adults with locally advanced or metastatic nonsquamous non-small-cell lung cancer (NSCLC) who have already undergone chemotherapy. [More]
Added benefit of lung cancer drug not proven, says IQWiG

Added benefit of lung cancer drug not proven, says IQWiG

Afatinib (trade name: Giotrif) has been approved since April 2016 for the treatment of adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) of squamous histology who have already received chemotherapy. [More]
Added benefit not proven for orphan drug in treatment of adults with stomach cancer

Added benefit not proven for orphan drug in treatment of adults with stomach cancer

Ramucirumab (trade name: Cyramza) is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours. [More]
New study reports long-lasting cognitive impairments in mice after chemotherapy treatment

New study reports long-lasting cognitive impairments in mice after chemotherapy treatment

Women undergoing chemotherapy for breast cancer have long complained of lingering cognitive impairments after treatment. [More]
Colorectal tumors present epigenetic heterogeneity, study finds

Colorectal tumors present epigenetic heterogeneity, study finds

A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program of Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at University of Barcelona discovers that colorectal tumors present epigenetic heterogeneity that relates to the clinical course of the disease. [More]
New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

A new measurement standard developed by the National Institute of Standards of Technology has been used successfully by the Frederick National Laboratory for Cancer Research to check the performance of next-generation DNA-sequencing technologies for evaluating gene variations associated with an increased risk of breast cancer. [More]
Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

The lack of oxygen in tumor cells changes the cells' gene expression, thereby contributing to the growth of cancer. [More]
MDI Biological Laboratory receives NIH grant for research on peripheral neuropathy

MDI Biological Laboratory receives NIH grant for research on peripheral neuropathy

The MDI Biological Laboratory has announced that it has received a grant of $456,500 over two years from the National Institutes of Health for the study of peripheral neuropathy. [More]
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